The Menopause Rating Scale (MRS): comparison with Kupperman index and quality-of-life scale SF-36

Schneider, H. P. G.; Heinemann, L.; Rosemeier, Hans Peter; Potthoff, Peter; Behre, Hermann M.

doi:10.3109/13697130009167599

Cited by 126 publications

(80 citation statements)

References 9 publications

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“…The study proved the MRS to be a much more sound and accurate instrument than the Kupperman Index in that it had no intuitive weighting factors, and the differences between scores could easily be explained by the domains resulting from factor analysis. Kendall's s-b coefficient and Pearson's correlation coefficient both demonstrated a high degree of association between the results of both instruments [40]. Of much more significance were the results of the comparison between the MRS and the SF-36.…”

Section: Menopausal Symptoms List (Msl) (1997)mentioning

confidence: 96%

Literature review of instruments to assess health-related quality of life during and after menopause

2005

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Section: Menopausal Symptoms List (Msl) (1997)mentioning

confidence: 96%

Literature review of instruments to assess health-related quality of life during and after menopause

2005

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“…It facilitates comparisons of menopausal symptoms between different groups of women under different conditions and allows to measure pre-to post-treatment changes [2,5,6]. The CGIC is a 7-point Likert scale ranging from 0 (not assessed), 1 (very much improved), 2 (much improved), 3 (minimally improved), 4 (no change), 5 (minimally worsened), 6 (much worsened) to 7 (very much worsened).…”

Section: Discussionmentioning

confidence: 99%

“…Among these scales the Menopause Rating Scale II (MRS-II) can be considered as an age and condition specific instrument that can be utilised to monitor the progress of menopausal symptoms as well as to compare the effects of different therapeutic agents [2].…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of a Herbal Formula in Women with Menopausal Syndrome

Yakoot¹,

Salem

Omar

2011

Forsch Komplementmed

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Background: Lady 4 is a combination of 4 natural components (evening primrose oil, damiana, ginseng, royal jelly) with a known history of traditional use for menopausal symptoms. Objective: To study efficacy and safety of Lady 4 in women suffering from menopausal syndrome. Methods: 120 women with menopausal symptoms were randomised into an experimental group treated with 2 capsules of Lady 4 daily and a control group treated with placebo. The outcome was measured by the Menopause Rating Scale II (MRS-II). Results: There was a statistically significant improvement in the MRS-II score in both groups after 2 and 4 weeks of treatment, but the improvement was significantly better in the Lady 4 group (p < 0.001). 86.7% in the Lady 4 group and 56.7% in the placebo group rated the therapy success as ‘much improved’ or ‘very much improved’. Conclusion: Lady 4 may be beneficial in the treatment of menopausal syndrome and can be used as a safe natural promoter of health and well-being in women during the menopausal transition.

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“…Additionally, caution must be used when examining HRQoL small group mean values and some [59] suggest examining repeat measures with an individual patient as a more robust method of analysis, which was also examined in this study. Longer monitoring, or use of a disease-specific measurement tool, such as the Menopause Rating Scale [60][61] or the combination of a general HRQoL and disease-specific scale may be important for future studies.…”

Section: Discussionmentioning

confidence: 99%

Pilot Study: Absorption and Efficacy of Multiple Hormones Delivered in a Single Cream Applied to the Mucous Membranes of the Labia and Vagina

Glaser¹,

Zava²,

Wurtzbacher³

2008

Gynecol Obstet Invest

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Background/Aims: There is a lack of evidence in the literature supporting vaginal application of a combination hormone-containing cream for local and systemic symptom relief. This pilot study examined the extent of absorption of a single cream containing estriol, estradiol, progesterone, DHEA, and testosterone. Methods: A combination cream was administered to 12 postmenopausal women in two differing doses over two independent time periods. Following 28 days (arm 1) and an additional 14 days (arm 2), measurement of hormones in saliva and blood and measurements of symptom relief, patient tolerability, and health-related quality of life (HRQoL) were obtained. Results: The dosage and time of evaluation for study arm 1 was not ideal for providing documented increases in hormone levels. HRQoL measurements supported measured improvement in this arm. The second arm did document absorption of the various hormones when given vaginally. Conclusion: This study is the first documenting systemic absorption of multiple hormones by both saliva and blood as well as improvement of HRQoL. This therapy was generally well-tolerated with only 2 patients experiencing minor irritation, not necessitating discontinuation. Additional studies in larger numbers of patients will provide better knowledge for clinicians wanting to provide similar therapy at the lowest effective dose.

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The Menopause Rating Scale (MRS): comparison with Kupperman index and quality-of-life scale SF-36

Cited by 126 publications

References 9 publications

Literature review of instruments to assess health-related quality of life during and after menopause

Literature review of instruments to assess health-related quality of life during and after menopause

Effectiveness of a Herbal Formula in Women with Menopausal Syndrome

Pilot Study: Absorption and Efficacy of Multiple Hormones Delivered in a Single Cream Applied to the Mucous Membranes of the Labia and Vagina

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