The Mechanism of Schiff Base Formation of Some Arylidenes‐p‐Aminosalicylic Acid

Abstract

Key Word Index-Kinetic study of some schiff base formation.

High yield accelerated reactions in nonvolatile microthin films: chemical derivatization for analysis of single-cell intracellular fluid

“…To characterize the performance of such a microthin film reactor, the Schiff base reaction between a set of primary amines and saccharides ( Scheme 1 ) was studied and the data are compared to bulk reactions run under traditional bulk, neat, and paste conditions. The reasons for this particular choice are (i) Schiff base formation is a reversible reaction with a modest equilibrium constant 34 , 35 and a reaction rate constant which makes it very difficult to perform chemical derivatization in small volume samples, (ii) identification and quantification of bioactive molecules like saccharides in tissues and single cells is an important task which could lead to deeper understanding of metabolic pathways, 8 , 9 cell heterogeneity 36 – 40 and even to the discovery of new drugs 10 – 12 and (iii) imine formation is an attractive route to efficient ionization of sugars.…”

Complete and Versatile Post‐Synthetic Modification on Iron‐Triazole Spin Crossover Complexes: A Relevant Material Elaboration Method

“…In fact, the presence of electron withdrawing groups like for the nitrobenzaldehyde derivatives results in a more stable intermediate (hemiaminal) that leads to a slower dehydration, in agreement with previous studies. [84][85][86] On the other hand, the presence of an electron donor group such as the methoxy substituent leads to faster reactions.…”

Crosslinking method of hyaluronic-based hydrogel for biomedical applications

“… 50 Schiff bases also serve as versatile ligands for arranging a variety of metal ions in different coordination geometries and oxidation states. 51 …”

“…50 Schiff bases also serve as versatile ligands for arranging a variety of metal ions in different coordination geometries and oxidation states. 51 The polysaccharide derivatives alginate, dextran, chitosan, and HA are extensively used biopolymers to prepare injectable hydrogels exploiting the Schiff-base reaction. [52][53][54][55] In the case of polymers with cis-glycols, the introduction of aldehyde functionality by periodate oxidation is an easy approach, particularly for biopolymers.…”