The influence of tin compounds on the dynamic properties of liposome membranes: A study using the ESR method

Abstract

Abstract:The influence of organic and inorganic compounds of tin on the dynamic properties of liposome membranes obtained in the process of dipalmitoylphosphatidylcholine (DPPC) sonication in distilled water was investigated. This was carried out by means of the spin ESR probe method. The probes were selected in such a way as to penetrate different areas of the membrane (a TEMPO probe, 5-DOXYL stearic acid, 16-DOXYL stearic acid). Four compounds of tin were chosen: three organic ones, (CH 3 ) 4 Sn, (C 2 H 5 ) 4 Sn and (C 3 H 7 ) 3 SnCl, and one inorganic one, SnCl 2 . The investigated compounds were added to a liposome dispersion, which was prepared prior to that. The concentration of the admixture was changed within the values from 0 to 10%-mole in proportion to DPPC. The studies indicated that the chlorides of tin display the highest activity in their interaction with liposome membranes. Since these compounds have ionic form in a water solution, the obtained result can mean that this form of admixture has a considerable influence on its activity. Furthermore, it was found that there is a slightly stronger influence of tin compounds with a longer hydrocarbon chain on changes in the probes' spectroscopic parameters.

Effects of Different Phases of Cigarette Smoke on Lipid Peroxidation and Membrane Structure in Liposomes

“…10). Despite that the literature data indicate that an LPO intensification results in a decrease of the S value, [58,59,61,62] from our point of view, these changes could not be explained solely by oxidative processes. Thus, the data disclosed above reveal that the cigarette smoke significantly modifies the different regions of liposomes and these modifications are not merely of oxidative origin.…”

Leaching behaviour and environmental risk assessment of heavy metals from electronic solder in acidified soil

“…Sn can poison organisms due to its ability to accumulate in living tissues and its commonness in nature. Symptoms of tin poisoning include neurological disorders (Man et al 2006). Therefore, the problem of Sn pollution from the solders is not negligible.…”

Liposomes modified by mono- and bis-phthalocyanines: A comprehensive EPR study

“…As reported elsewhere, organometallic compounds may more or less affect the membrane's physical parameters [12][13][14]. Likewise, our previous investigations were focused mainly on structural deviations induced within the lipid arrangement by different amounts of such additives [15][16][17][18][19] including the effect of the interaction time [20,21]. On the other hand, the present work contains some novel aspects regarding the behavior of intercalated phospholipid systems, in particular the impact of the dopant's molecular structure and its static electrical charge.…”