The influence of structural design of PLGA/collagen hybrid scaffolds in cartilage tissue engineering

Fabrication of tough poly(ethylene glycol)/collagen double network hydrogels for tissue engineering

“…In particular, type I collagen is extensively used in tissue engineering for scaffolding purposes. 17,18 Col hydrogels have shown numerous advantages in cell adhesion, growth, and proliferation because of cellcollagen interactions. 19 Thus, Col hydrogel based materials are widely applied in the fields of skin and wound repairing, as well as artificial patches.…”

Nanomaterials for cartilage tissue engineering

“…Tissues grown in collagen-alginate hydrogels expressed less collagen II than those in collagen-based hydrogels. In another study, bovine chondrocytes were cultured on hybrid scaffolds made of collagen I and PLGA, which were then transplanted subcutaneously into mice [64]. The PLGA mesh acts as a skeleton and the collagen microsponges aided cell attachment and growth.…”

Tissue Engineering for Tissue and Organ Regeneration

“…Recently the possibility of using injectable scaffolds in cardiac cell therapy has been explored by interfacing murine mesenchymal (mMSC) and cardiac stem cell (mCSC) lines with poly-lactic acid (PLA) microspheres having a diameter of 30 and 100 μm. Preliminary in vitro experiments demonstrated that such cells can be grown onto PLA microspheres while preserving their phenotype, but the formation of cell clumps can hamper the application of this technique [38]. The use of dynamic seeding techniques (i.e.…”