The Influence of Smoking on Vitamin C Status During the Third Trimester of Pregnancy and on Vitamin C Levels in Maternal Milk

Ortega, RM; López-Sobaler, Ana M.; Quintas, M E; Martínez, Rosa María Goig; Andrés, Pedro

doi:10.1080/07315724.1998.10718779

Cited by 42 publications

(29 citation statements)

References 18 publications

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“…Nutrient intake is decreased in pregnant women as compared to non pregnant women [38] . It is possible that dietary vitamin C intake may have been lower in our studied population than in other studies.…”

Section: Discussionmentioning

confidence: 99%

Antioxidant Status of Neonates Exposed in utero to Tobacco Smoke

Fayol¹,

Gulian

Dalmasso

et al. 2005

Neonatology

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To investigate the influence of maternal smoke exposure on neonatal and maternal antioxidant status, 39 mothers who were active smokers, 14 mothers exposed to environmental tobacco smoke (ETS), 17 controls, and their newborns were included in a prospective, controlled study. Plasma total antioxidant capacity, measured as total radical-trapping antioxidant parameter (TRAP) and ferric reducing antioxidant power (FRAP), and concentrations of specific antioxidants were measured in cord and in maternal blood. A similar, significant increase in ceruloplasmin concentration was observed in neonates born to actively smoking mothers and in those born to ETS exposed mothers. Uric acid and TRAP concentrations were significantly increased in ETS-exposed newborns and their mothers, compared to newborns and mothers from the active smoking and no-exposure groups with a trend towards increased uric acid, TRAP and FRAP concentrations being observed in the active smokers group. Neonatal and maternal antioxidant concentrations correlated significantly, except for ceruloplasmin. Cord blood vitamin A, E and C concentrations were unaffected by smoke exposure. These results show that maternal active smoking as well as ETS exposure significantly affect neonatal and maternal antioxidant status.

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Section: Discussionmentioning

confidence: 99%

Antioxidant Status of Neonates Exposed in utero to Tobacco Smoke

Fayol¹,

Gulian

Dalmasso

et al. 2005

Neonatology

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“…[18][19][20] Importantly, this study revealed inferior antioxidant properties of breast milk from smoking mothers. This finding substantiates further research on the effects of inferior antioxidant properties of breast milk on the health status of infants born to smoking mothers.…”

Section: Discussionmentioning

confidence: 99%

Maternal smoking decreases antioxidative status of human breast milk

Zagierski

Szlagatys-Sidorkiewicz

Jankowska

et al. 2011

J Perinatol

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Objective: To evaluate the influence of maternal smoking on antioxidative capacity and intensity of oxidative damage in breast milk.Study Design: The study group (n ¼ 30) was comprised of postpartum women who declared smoking more than five cigarettes per day during pregnancy and lactation (confirmed by the urinalysis of cotinine concentration), and their newborns. Control group included 29 nonsmoking postpartum women and their newborns. Colostrum samples were collected on the 3rd day after delivery and breast milk samples between the 30th and the 32nd day after delivery. Morning maternal and neonatal urine samples were obtained on the day of the mature milk sampling. Isoprostane concentrations in colostrum/mature milk and urine were determined immunoenzymatically. Total Antioxidant Status (TAS) of colostrum/breast milk was determined by Rice-Evans and Miller method.Result: Colostrum TAS in smokers was significantly lower than in nonsmokers (P ¼ 0.006). In both groups, the TAS of mature milk was higher compared with colostrum, but significant differences were observed amongst smokers only (P ¼ 0.001). In smokers the isoprostane concentration of mature milk was significantly higher than the colostrum concentration (P ¼ 0.001). Significant inverse correlation between maternal urinary isoprostane concentration and the TAS of mature breast milk was observed in smokers (R ¼ À0.525, P ¼ 0.023), but not in non-smokers (R ¼ 0.161, P ¼ 0.422).Conclusion: This study revealed that maternal smoking triggers harmful effects on an infant by impairing pro-oxidant-antioxidant balance of breast milk.

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“…Vitamin C deficiency could lead to inadequate antioxidant defence. Moreover, the lower vitamin C 18 and E 16 concentrations in the milk of smoking mothers could mean their children face an even greater challenge.…”

mentioning

confidence: 99%

Dietary guidelines for pregnant women

Ortega

2001

Public Health Nutr.

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The nutrition of pregnant women is decisive in the course of gestation and the health of both mother and child. However, in the Spanish population, clinical monitoring of nutrition is rare, the control of bodyweight receiving most attention. Many studies show that pregnant women take too much fat and too little carbohydrate, and that intakes of fibre and several trace elements are lower than recommended.

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The Influence of Smoking on Vitamin C Status During the Third Trimester of Pregnancy and on Vitamin C Levels in Maternal Milk

Abstract: If the concentration of antioxidants (vitamin C) in smokers' breast milk is also lower, this might aggravate the peroxidation problems of their newborn.

Cited by 42 publications

References 18 publications

Antioxidant Status of Neonates Exposed in utero to Tobacco Smoke

Antioxidant Status of Neonates Exposed in utero to Tobacco Smoke

Maternal smoking decreases antioxidative status of human breast milk

Dietary guidelines for pregnant women

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