The influence of immune status, age, and sex on Majocchi granuloma: a review of 52 cases from a tertiary level hospital and published Korean cases in literature

Abstract

The results of our study revealed that distinctive features of MG exist based on immune status, age, and sex.

Majocchi's granuloma on the face: dermoscopy and reflectance confocal microscopy

“…Majocchi's granuloma is an atypical and uncommon presentation of dermatophytic infection in the dermal and subcutaneous tissue, first described in 1833 by Domenico Majocchi . It has also been reported as trichophyton granuloma or nodular granulomatous perifolliculitis . Most commonly, Trichophyton rubrum is identified, followed by Trichophyton violaceum , Trichophyton mantagrophytes , Microsporum audouinii , Microsporum gypseum , Mycrosporum canis , and Epidermophyton floccosum …”

Clinical and mycological study of 42 cases of dermatophytic granuloma (Majocchi granuloma)

“…The most common clinical manifestations were the nodular (88 %) and ulcerative (7 %) types. The superficial plaque type was infrequent, and often misdiagnosed as tinea corporis, suspected due to the lack of treatment response [4,5].…”

“…The infection affects the dermis or deeper tissues, and a biopsy is essential to confirm the diagnosis [2]. In recent years, DG cases have been reported relatively frequently, probably due to the increased incidence of predisposing factors (type 2 diabetes, hematologic diseases, and chronic use of topical or systemic corticosteroids) [3,5,6].We performed a retrospective study of 42 cases of DG from a period of 27 years in our dermatology department. The cases were confirmed by mycological tests (direct examination and culture).…”

Klinische und mykologische Untersuchung von 42 dermatophytischen Granulomen (Majocchi‐Granulome)

“…In den letzten Jahren wurde relativ häufig über dermatophytische Granulome berichtet, wahrscheinlich aufgrund einer erhöhten Inzidenz von prädisponierenden Faktoren (Typ-2-Diabetes mellitus, hämatologische Erkrankungen sowie die chronische Anwendung [topisch oder systemisch] von Glukokortikosteroiden) [3,5,6]. Wir führten eine retrospektive Studie anhand von 42 DG-Fällen innerhalb eines Zeitraums von 27 Jahren (1993-2019) in unserer dermatologischen Abteilung durch.…”

“…Das Durchschnittsalter der Patienten betrug 32 Jahre. Bei Frauen waren DG häufiger (64 %), obwohl frühere Studien eine höhere Inzidenz bei Männern (61-71 %) berichtet hatten [1, 3,5,7,9]. Die Zeit vom Auftreten der ersten klinischen Symptome bis zur Diagnose betrug 4,3 Monate; in der Literatur wird in den meisten DG-Fällen von einer lang andauernden Krankheitsentwicklung berichtet.…”