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2005
DOI: 10.1016/j.jbiomech.2004.02.015
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The influence of design, materials and kinematics on the in vitro wear of total knee replacements

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Cited by 285 publications
(244 citation statements)
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“…Elevated crosslinked polyethylenes reduce wear rates in TKA simulator studies [8,19,21], but this benefit must be balanced with the mechanical changes that accompany the increased crosslinking, specifically reduced fracture toughness and reduced resistance to fatigue crack propagation [3,6,10].…”
Section: Discussionmentioning
confidence: 99%
“…Elevated crosslinked polyethylenes reduce wear rates in TKA simulator studies [8,19,21], but this benefit must be balanced with the mechanical changes that accompany the increased crosslinking, specifically reduced fracture toughness and reduced resistance to fatigue crack propagation [3,6,10].…”
Section: Discussionmentioning
confidence: 99%
“…Over 1 billion cycles of testing have been completed and published in the last decade in both pin-on-plate and knee simulator studies, providing a robust platform for standardized comparison of both materials and designs. Knee simulator studies were undertaken on the Prosim knee simulator (Simulation Solutions, Manchester, UK) [4,11,12,22]. Two sets of tests were carried out: (1) comparison of fixed-bearing PFC sigma knee to the PFC sigma rotating platform knee (DePuy International) and (2) comparison of sigma fixed-bearing knee with low conforming fixed-bearing knee, where the curved tibial insert was replaced by a flat polymer insert.…”
Section: Methodsmentioning
confidence: 99%
“…The irradiation level was between 2.5 and 4 MRad, indicating moderate levels of cross-linking, which was available for both types of knee design. Tests were carried out using the ISO loading profile 2.6 KN with a medial offset load and flexion extension waveform of 0°to 58°r epresenting standard gait [22]. For high kinematic conditions displacement was controlled with internal external rotation set at ± 5°as in the natural knee and anterior posterior displacement set at 0 to 10 mm [22].…”
Section: Methodsmentioning
confidence: 99%
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