The Influence of Climate on the Respiratory Function of the Healthy Population of Vladivostok and Patients With Bronchopulmonary Pathology

Abstract

Introduction. The climatic factors affect the mucous membrane of the respiratory tract contacting with the environment. The investigation of pulmonary ventilation plays a leading role in the diagnosis of bronchial obstruction in response to an external stimulus. Material and methods. The study included a healthy population of the city and patients with chronic catarrhal nonobstructive bronchitis (CCNB), controlled and uncontrolled asthma (131 people). The respiratory function (RF) was estimated by spirography and body plethysmography. Meteorological conditions were evaluated from the point of view of contrasting weather changes (on the survey day, on 1st and 2nd days before the survey). The degree of the climatic impact on RF was determined by the statistical module “Discriminant analysis”, used to a group of RF indices relatively adverse levels of impact of the monsoon climate. Results. The low level of the responsiveness in a healthy urban population was identified. The negative impact of climatic indices on the respiratory system in CCNB patients was observed mainly in extreme weather conditions. The influence of climatic conditions on patients with asthma depends on the level of the disease control. Discussion. The influence of climatic conditions was found to be within the adaptive and compensatory responses in a group of healthy people and CCNB patients. We assumed the use of basic drugs in patients with asthma without signs of bronchial obstruction to reduce the susceptibility of the receptors of the bronchi to the negative climatic impact. The greatest negative RF response to the impact of monsoon climate manifested both in static and in dynamic weather conditions, was observed in patients with uncontrolled asthma. It was associated with the impaired pulmonary ventilation. Conclusion. The results indicate the Far East monsoon climate to be an important risk factor for the exacerbation in patients with respiratory diseases.

Assessing Short-Term Weather-Induced Immune Response In Russian Far East Residents With Respiratory Diseases

“…Most healthy people are virtually insensitive to weather changes. At the same time, there are many people exhibiting increased sensitivity to fluctuations in meteorological conditions, mainly patients with respiratory diseases [4]. Such people are called weather dependent.…”

“…The responses of the body to the impact of weather conditions are characterized by weather dependence (in healthy people) and meteoropathic responses (in patients), which aggravate the course of chronic diseases [6,7]. As a rule, pathological weather dependence that affects the homeostasis of biological dynamic systems is based on the exhaustion of the reserve adaptive and compensatory capabilities of the body, which leads to desynchronization and dysfunction of the internal systems of the body [4,8].…”

Association Between The Respiratory Organ’s Morbidity Of Adult Population And Territorial Aridity

“…Respiratory diseases are one of the main causes of temporary disability and mortality in the Russian Federation, accompanied by large economic losses. Bronchopulmonary diseases are multifactorial diseases, their formation and the nature of the course are determined by a number of endogenous and exogenous causes, among which the special role of the climatic factor should be noted (Veremchuk et al, 2018a). A correlation has been established between the climatic and geographical region of residence and the formation of chronic nonspecific lung diseases (Gambaryan et al, 2015), in particular, bronchial asthma (Manocha et al, 2021), as well as the severity of its course.…”