The influence of an essential fatty acid deficient-diet on the reproductive performance of female rats

Parlanti, Iris A.; Orellana, Liliana

doi:10.1051/rnd:19850701

Cited by 5 publications

(5 citation statements)

References 36 publications

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“…A high post-natal mortality was observed in the pups born to dams fed on an EFA-deficient diet in the present experiments. Similar rates of pup mortality were reported in litters born to first- (Parlanti & Orellana, 1985) and secondgeneration EFA-deficient rats (Sinclair & Crawford, 1973 ;Alling et al 1974). In our study, triene: tetraene for liver phospholipids in expired pups had a mean value of 0.7, a value not exceptionally high when compared with those observed in deficient animals in the postweaning experiments.…”

Section: Discussionsupporting

confidence: 87%

“…In addition to the direct, or indirect, effects on protein and energy balance, several animal experiments have demonstrated that maternal EFA deficiency during pregnancy and lactation resulted in growth retardation in the foetuses (Menon et al 1981) and offspring (Alling et al 1974;Menon et al 1981;Parlanti & Orellana, 1985). Arachidonic acid in particular has been shown to have growth-promoting effects mediated through its role in the synthesis of prostaglandins and other eicosanoids (Koletzko & Braun, 1991).…”

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confidence: 99%

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Protein utilization, growth and survival in essential-fatty-acid-deficient rats

1996

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The relationship between essential fatty acids (EFA) deficiency and the utilization of dietary protein, growth rate and survival of offspring was investigated in rats during development and reproduction. EFA deficiency was induced by feeding a 200 g casein/kg-based diet containing 70 g hydrogenated coconut oil (HCO)/kg as the only source of fat. The conversion efficiency of dietary protein was assessed as net protein utilization (NPU), using a 10 d comparative carcass technique. Consumption of the deficient diet during the 10 d assay period induced biochemical changes characteristic of mild EFA deficiency in humans (triene:tetraene 0.27 (SD 0.04) compared with 0.026 (SD 0.004) for wn-deficient controls), but there were no significant changes in growth rate or protein utilization. These variables were also unchanged when the deficient diet was fed for an additional 7 d before the assay, although triene: tetraene increased to 0.8 (SD 0.02). Feeding the deficient diet for 63 d before assay produced severe EFA deficiency (triene:tetraene 1.4 (SD 0.3) u. 0.036 (SD 0.005) for controls), a fall in growth rate (25% during assay period), and NPU (31.5 (SD 0.63) v. 39-0 (SD 0.93) for controls). These severely-EFA-deficient animals had a 30% higher fasting-resting rate of energy metabolism than that of age-matched controls. However, there was no change in the rate of endogenous N loss. Voluntary energy consumption was increased in animals fed on deficient diets, either with 200 g protein/kg, or protein free. The reduced efficiency of protein utilization could be entirely accounted for by the restricted amount of energy available for growth and protein deposition. Consumption of an EFA-deficient diet during pregnancy and lactation resulted in high mortality (11 % survival rate at weaning compared with 79% for controls) and retarded growth in the preweaning offspring. It is concluded that animals are particularly sensitive to EFA deficiency during reproduction and pre-and post-natal stages of development. However, after weaning only severe EFA deficiency retarded growth, primarily through changes in energy balance.

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Section: Discussionsupporting

confidence: 87%

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confidence: 99%

Protein utilization, growth and survival in essential-fatty-acid-deficient rats

1996

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“…It is well established that essential-fatty-acid deficiency in the rat leads to degeneration of the testis, with concomitant infertility, in males (Ahluwalia et al 1967;Marzouki & Coniglio, 1982). In females, though they may conceive, fetuses are often reabsorbed, animals abort or young ones are stillborn (Mohrhauer & Holman, 1967;Menon et al 198 I ) ; the frequency of irregular oestrous cycles, with an increased incidence of prolonged dioestrus, prolonged period of gestation, reduced litter size, and increased pup mortality, are usually significantly higher (Satomi & Matsuda, 1973;Parlanti & Orellana, 1985). It seems possible that high concentrations of trans-fatty acid isomers, as found in hydrogenated dietary oils, could also adversely affect the reproduction of laboratory rats, though that effect would be more probable at lower levels of essential fatty acids (Holman & Aaes-Jorgensen, 1956;Alfin-Slater et al 1957;Emken, 1984).…”

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confidence: 99%

Effects of dietarytrans-fatty acids on reproductive performance of Wistar rats

Hanis

Zidek

Šáchová³

et al. 1989

Br J Nutr

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1. Wistar rats were fed for three successive generations on a semi-purified diet, in which the fat was provided by butter, sunflower oil, rapeseed oil or hydrogenated vegetable fat, differing in the content of cis,cis-18:2 and trans-18 : 1 fatty acids. Effects of these fats on the composition of adipose tissue and reproductive performance were studied. Fatty acids were analysed using high-performance liquid chromatography. 2.The fatty acid pattern of adipose tissue was closely related to dietary fat composition and, established in the first generation, did not change significantly in successive generations of rats.3. Hydrogenated fat adversely affected litter size, sperm morphology and regularity of oestrous cycle, and prolonged the period of gestation in experimental animals. Differences observed between the generations were not significant.4. Hydrogenated fat decreased the level of serum testosterone in males, but the differences observed in levels of serum progesterone in females were not apparently related to the dietary tran.r-fatty acids.

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“…In fact, the reviewed data and information by various researchers showed an improvement of seminal characteristics in males as well an enhancement of the fertility and prolificacy in female animals when fed on ration contained vegetable oils, in one the hand as have been found in rabbits (Christ et al, 1996), horses (Squires, 2006), rats (Naseem et al, 2007), boars (Estienne et al, 2008), dogs (Rocha et al, 2009), turkeys (Zaniboni andCerolini, 2009), quails (Al-Daraji et al, 2010), and ducks (Ghonim et al, 2010). On the other hand, it is well established that essential-fatty-acid deficiency leads to degeneration of the testis with concomitant infertility (Ahluwalia et al, 1967;Marzouki and Coniglio, 1982;Wathes et al, 2007), and leads to prolonged diestrus, abortion, or giving birth to stillborn fetuses (Menon et al, 1981;Parlanti and Orellana, 1985). Meanwhile, Pascual et al (1999) did not encounter any differences in the prolificacy of does rabbits supplemented with soybean oil ration (at 99 to 117 g per kg DM) compared to control diet (at 26 g per kg DM), as well Kelso et al (1997) who observed no differences in sperm motility during a 49-week experiment when fed a rich ω 3 or ω 6 diets to turkeys, while Yaakub et al (2009) found out that spermatogenesis was altered in rams fed on palm kernel cake-based ration.…”

Section: Introductionmentioning

confidence: 99%

Can feed supplementation of the refined vegetable oils enhance the seminal quality of rabbit bucks (Oryctolagus cuniculus)?

Okab¹,

Nasser²,

El-Banna³

et al. 2017

Anim Reprod

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Exploring new feeding strategies are a necessary aspect for improving the reproductive performance in rabbits. Twenty healthy rabbit bucks with a mean live body weight of 1.01 kg (SD = 0.12) and age of 6 months old were used for a period of 17 weeks to examine the influence of feeding soybean and sunflower oils on their reproductive performance. Rabbits were randomly assigned into 4 groups (5 bucks/group), where bucks in the 1st group, served as a control, were fed for 14 weeks on a standard ration without any oil supplementation, while bucks in the 2nd, 3rd, and 4th groups received -on the basis of the inclusion rate-a ration supplemented with 3% soybean oil, 3% sunflower oil, and 1.5% soybean oil plus 1.5% sunflower oil, respectively. Climatic, bio-physiological, blood and seminal measurements were all been determined. The obtained results suggested that offering rations supplemented with soybean and/or sunflower oils at the level of 3% of DM to rabbit bucks had no impacts on their health status, based on the findings that feed conversion ratio, blood hematology as well as liver and kidney functions were all not altered; thereby, indicating that the refined vegetable oils can be safely supplemented into rabbits rations. Most importantly, the collected evidences proposed that supplementing vegetable oil-enriched rations to rabbit bucks during their adulthood may demonstrate subsequent positive influences on their reproductive characteristics as early as the 3rd/4th week after feeding on such oils. This was generally manifested by the higher (P < 0.05) sperm concentration, total sperm output, percentage of motile sperms, as well as the lower (P < 0.05) percentages of dead and altered acrosomal sperms that observed in bucks compared to their control twins. Based on the obtained results herein, feeding rations supplemented with soybean and/or sunflower oils at the level of 3% of DM to rabbit bucks during their adulthood would produced an acceptable semen quality compared to the control bucks. Research dealing with such aspect may improve our understanding of the nutritional requirements and production of rabbits. However, further researches are definitely imperative because of the number of bucks per group was considerably low in the current experiment.

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The influence of an essential fatty acid deficient-diet on the reproductive performance of female rats

Abstract: Summary. Several Introduction.

Cited by 5 publications

References 36 publications

Protein utilization, growth and survival in essential-fatty-acid-deficient rats

Protein utilization, growth and survival in essential-fatty-acid-deficient rats

Effects of dietarytrans-fatty acids on reproductive performance of Wistar rats

Can feed supplementation of the refined vegetable oils enhance the seminal quality of rabbit bucks (Oryctolagus cuniculus)?

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