2012
DOI: 10.20473/j.djmkg.v45.i4.p228-233
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The increasing of fibroblast growth factor 2, osteocalcin, and osteoblast due to the induction of the combination of Aloe vera and 2% xenograft concelous bovine

Abstract: Background: To make a successfull denture prominent ridge is needed, preservation on tooth extraction socket is needed in order to prevent alveol bone resorption caused by revocation trauma. An innovative modification of the material empirically suspected to be able reduce inflammation caused by the revocation trauma is a combination of Aloe vera and xenograft concelous bovine (XCB) and Aloe vera is a biogenic stimulator and accelerating the growth of alveolar ridge bone after tooth extraction. Purpose: The re… Show more

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Cited by 7 publications
(6 citation statements)
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“…1 Alveolar bone resorption will remain and even can cause more than 40 -60% ridge volume loss during the first three years post tooth extraction. [2][3][4] The damage of the alveolar bone, unfortunately, can cause failure or the instability of dentures or dental implant placement. 4,5 Ridge preservation and grafting materials can be used to prevent bone loss and to regenerate alveolar bones.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…1 Alveolar bone resorption will remain and even can cause more than 40 -60% ridge volume loss during the first three years post tooth extraction. [2][3][4] The damage of the alveolar bone, unfortunately, can cause failure or the instability of dentures or dental implant placement. 4,5 Ridge preservation and grafting materials can be used to prevent bone loss and to regenerate alveolar bones.…”
Section: Introductionmentioning
confidence: 99%
“…There are developments of a combination of natural and synthetic graft materials or polymers used to achieve alveolar bone resorbtion. 1,2 Actually, bone tissue engineering innovation has recently developed scaffold that can be absorbed by the body, such as chitosan polymers material, in order to accelerate the replacement of damaged tissue as well as to proliferate, differentiate and maintain tissue function. 7 The application of chitosan to the tooth extraction socket of Rattus norvegicus can increase the number of osteoblasts, fibroblasts and type I collagen on 7 and 14 days of observation.…”
Section: Introductionmentioning
confidence: 99%
“…In addition, macrophages activate M2 which will stimulate the secretion of IL-10 and growth factors such as VEGF, FGF, BMP-2, and TGF-β1 which are important for bone healing, with increased expression of growth factors, will stimulate increased angioblast cell proliferation, fibroblasts, osteoblasts which are important for bone healing, with increased expression of growth factors, will stimulate increased angioblast cell proliferation, fibroblasts, osteoblasts which are important for bone healing will form extracellular bone matrix. 13 Flavonoids are powerful antioxidants that can reduce peroxidase, increase the speed of epithelialization, and antimicrobials. Decreased lipid peroxidase by flavonoids will prevent necrosis, improve vascularity, and increase the viability of collagen fibers.…”
Section: Discussionmentioning
confidence: 99%
“…After removal, the socket was irrigated with sterile distilled water, given 0.1 ml of materials according to the group: control group (PEG), EEP group (EEP gel), BBG group (BBG gel), and combination group (EEP-BBG gel). Simple suturing was subsequently performed with polyamide monofilament DS 12 3 / 8c, 12 mm, 6/10 met, 0.7 (Braun VetCare SA, Rubi, Spain) ( Kresnoadi, 2012 ) .…”
Section: Methodsmentioning
confidence: 99%