The in vivo and in vitro degradation behavior of poly(trimethylene carbonate)

Advanced microstructures based on poly(trimethylene carbonate) : microfabrication and stereolithography

“…[85] Linear (co)polymers and (co)polymer networks prepared from TMC and D,L-lactide or -caprolactone were shown to be compatible with a large number of cells: Schwann cells, human umbilical vein endothelial cells, rat cardiomyocytes, human skin fibroblasts, smooth muscle cells and mouse pre-myoblast C2C12 cells all showed good cell attachment and proliferation in vitro on the surface of these materials. Implantation experiments in small animals showed only a mild tissue response.…”

Biodegradable polymers for dental tissue engineering and regeneration

“…Structurally, such connections are hydrolytically stable but PCA possess rapid surface in vivo degradation, presumably due to enzymatic activity [232]. The most extensively studied polycarbonate is poly(trimethylene carbonate) (PTMC) which has a T g of −17 °C, elastomeric characteristics, slow degradation profile, and biocompatible degradation products [233].…”

Biodegradable stent

“…If the viscoelastic polymers are quickly increased, the rearranging time of the chains are shorter so that they become brittle; on the other hand, if they are slowly increased, the chains are rearranged so that they can be easily deformed. The physiochemical characteristics of the commercial biodegradable polymers are shown in Table 2 as follows [32][33][34][35][36][37][38][39][40][41][42][43][44][45][46]. Also, the glass transition temperature (T g ), an important physical characteristics in the polymers, was summarized.…”