The Importance of the Neutrophil-Lymphocyte Ratio in Patients with Idiopathic Peripheral Facial Palsy

Abstract

Objective. The purpose of this study was to investigate whether or not there was a correlation between the neutrophil-to-lymphocyte ratio (NLR) value and the severity of idiopathic peripheral facial palsy (IPFP) and to determine whether or not NLR could be used as an early predictive parameter in the prognosis of IPFP patients. Material and Method. This retrospective study was conducted on 146 patients who were diagnosed with IPFP. The control group comprised 140 patients. Patients with IPFP were categorized according to the House-Brackmann grading system (HBS). The NLR value was obtained by dividing the neutrophil value by the lymphocyte value. Results. In the IPFP group, the mean NLR value was 3.63 ± 2.74 and, in the control group, 1.84 ± 0.78. The mean NLR value was significantly higher in IPFP patients than in the control subjects (p < 0.0001). The mean NLR value in group A (Grades I-II ) was 2.61 ± 2.28, in group B (Grades III-IV) 3.22 ± 2.65, and in group C (Grades V-VI) 10.69 ± 6.30. Conclusion. We determined that as the severity of IPFP increased, the NLR value increased. The NLR value can be used as a prognostic factor in the early prediction of IPFP prognosis.

Evaluation of neutrophil-to-lymphocyte ratio in patients with symptomatic rhinitis

“…In a study, the NLR increased with increasing Bell's palsy grade. [29] In Behçet disease, which is a systemic inflammatory vascular disease, the NLR was also reported higher than healthy individuals. [30] However, despite high TNSS, we found no significant correlation between the NLR and disease severity in our study.…”

A Retrospective Analysis of Haemotologic Parameters in Patients with Bilateral Tinnitus

“…As a blood marker MPV shows platelet volume and gives information about platelet function. Highly MPV values were associated with more platelet aggregation and increased risk of ischemic injury (4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)21). There are many studies on MPV and tinnitus relationship.…”

“…Neutrophil-to-lymphocyte ratio was investigated in several studies as, predictive or prognostic marker of inflammatory processes, malignancies and cardiac diseases . It was also studied for otorhinolaryngologic diseases such as Bell Palsy, sudden hearing loss and nasal polyposis (5)(6)(7)24). This marker was also studied in tinnitus patients.…”

Comparison of Neutrophil/Lymphocyte Ratio and Trombocyte/Lymphocyte Ratio Values between Tonsillectomy and a Control Group

“…The frequency of studies on NLO and TLO has been increasing in recent years. A PubMed search revealed 339 papers written on NLO [1][2][3][4]. NLO and TLO have been designated as inflammatory markers that can be routinely studied in the peripheral blood without additional cost.…”

“…Because NLO and TLO are predictors of inflammation, the various fields in which they can be used are being highlighted in a number of new studies. For example, studies have been conducted not only on infections and cancers, but also peripheral facial paralysis, familial Mediterranean fever, vertigo, cholesteatoma, and adenoid vegetation [1][2][3][4][5][6]. Even so, in the literature there is only one study about NLO and TLO performed with patients who underwent tonsillectomy-a study conducted in 2015 in Turkey.…”