The impact of PM2.5 on asthma emergency department visits: a systematic review and meta-analysis

Fan, Jingchun; Li, Shulan; Fan, Chunling; Zhang, Bai; Yang, Kehu

doi:10.1007/s11356-015-5321-x

Cited by 196 publications

(128 citation statements)

References 42 publications

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“…These findings suggested that traffic-related PM 2.5 did greater harm to the human body, and that exposure to PM 2.5 pollution may pose an increased risk for respiratory tract disease, especially in children exposed to high concentrations of PM 2.5 . These results are consistent with those of previous reports [ 58 59 ] , as well as being more accurate than the results of a previous meta-analysis of case-control studies [ 60 ] . …”

Section: Discussionsupporting

confidence: 93%

Effect of exposure to ambient PM2.5 pollution on the risk of respiratory tract diseases: a meta-analysis of cohort studies

Liu

et al. 2017

J Biomed Res

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The International Agency for Research on Cancer and the World Health Organization have designated airborne particulates, including particulates of median aerodynamic diameter ≤ 2.5 μm (PM2.5), as Group 1 carcinogens. It has not been determined, however, whether exposure to ambient PM2.5 is associated with an increase in respiratory related diseases. This meta-analysis assessed the association between exposure to ambient fine particulate matter (PM2.5) and the risk of respiratory tract diseases, using relevant articles extracted from PubMed, Web of Science, and Embase. In results, of the 1,126 articles originally identified, 35 (3.1%) were included in this meta-analysis. PM2.5 was found to be associated with respiratory tract diseases. After subdivision by age group, respiratory tract disease, and continent, PM2.5 was strongly associated with respiratory tract diseases in children, in persons with cough, lower respiratory illness, and wheezing, and in individuals from North America, Europe, and Asia. The risk of respiratory tract diseases was greater for exposure to traffic-related than non-traffic-related air pollution. In children, the pooled relative risk (RR) represented significant increases in wheezing (8.2%), cough (7.5%), and lower respiratory illness (15.3%). The pooled RRs in children were 1.091 (95%CI: 1.049, 1.135) for exposure to <25 μg/m3 PM2.5, and 1.126 (95%CI: 1.067, 1.190) for exposure to ≥ 25 μg/m3 PM2.5. In conclusion, exposure to ambient PM2.5 was significantly associated with the development of respiratory tract diseases, especially in children exposed to high concentrations of PM2.5.

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Section: Discussionsupporting

confidence: 93%

Effect of exposure to ambient PM2.5 pollution on the risk of respiratory tract diseases: a meta-analysis of cohort studies

Liu

et al. 2017

J Biomed Res

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“…They will deep penetrate into the airways that directly induces inflammation and oxidative stress caused by the depletion of intracellular glutathione with consequent decrease in the oxidized glutathione/glutathione ratio. 6,7 Accordingly, oxidative stress can induce the production of pro-inflammatory cytokines, chemokines, and adhesion receptors. 7 Research on mechanisms underlying the adverse health effects of air pollution suggests a potential role for dietary interventions…”

Section: Introductionmentioning

confidence: 99%

The inflammatory potential of diet impacts the association between air pollution and childhood asthma

Mendes

Paciência

Rufo

et al. 2020

Pediatric Allergy Immunology

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Background: Inhalation of fine particulate matter (PM) can cause systematic inflammation and oxidative stress, which may further aggravate the development and progression of asthma. Although nutritional intake of fatty acids and antioxidants may attenuate some effects of fine PM, the role of the inflammatory potential of diet has not been addressed. Therefore, we aimed to investigate possible modulatory effects of dietary inflammatory potential on the association between indoor air pollution and childhood asthma-related outcomes.Methods: In a sample of 501 children (48.1% females, aged 7-12 years) from 20 public schools located in Porto, Portugal, we evaluated airway reversibility, exhaled nitric oxide levels, atopy, and current respiratory symptoms. Dietary inflammatory index was calculated based on information collected through a reported 24-hour recall questionnaire, and participants were categorized as having an anti-inflammatory or pro-inflammatory diet. Concentrations of indoor PM2.5 and PM10 were measured to assess indoor air quality. Generalized linear mixed models were used to investigate the proportion of effects explained by the exposure to PM2.5 and PM10.Results: After adjustment, the exposure effect of PM2.5 and PM10 levels on children with asthma was higher for those having a pro-inflammatory diet (OR = 1.44, 95% CI:1.01-2.21; and OR = 1.29, 95% CI: 1.03-1.68, respectively) compared to those having an anti-inflammatory diet. Conclusion:These findings suggest that the quality of diet might affect the association between indoor pollution and asthma in children, highlighting the relevance | 291 de CASTRO MeNdeS eT Al. de CASTRO MeNdeS eT Al.effect was estimated by odds ratio (OR) and 95% confidence interval (95% CI). Additionally, β and 95% CI were estimated for continuous variables. Lung function parameters, exhaled NO, and all subjective and objective measures of asthma were included as outcomes, considering "medical diagnosis" and "under asthma treatment" as primary outcomes and "positive bronchodilation" and "asthma symptoms" as secondary outcomes. The values of DII were grouped into one of the two categories according to the inflammatory potential of the diet: anti-inflammatory, when the values were below zero; and pro-inflammatory, when the values were higher. Shivappa et al's review pointed out 45 food parameters, and they were scored with +1, −1, or 0 according to their inflammatory effects: pro, anti, or null, respectively. Accordingly, we aggregated children based on their proor anti-inflammatory individual DII score. 17 No children obtained an individual score equal to 0. The estimates were assessed in several models: a model for main effects (Model 1); a model considering an interaction between PM2.5 or PM10 and dietary inflammatory index (Model 2); and a model adjusted for age, sex, exposure to tobacco at home, maternal smoking during pregnancy, atopy, body mass categories, and school (Model 3). Model 3 considered the interaction only if it was significant in Model 2. A 0.05 level of signi...

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“…The application of low‐cost particulate matter (PM) sensors is a fast growing area of research. It is long known that air pollution is an impediment to human health . Respirable particles, i.e., PM with an aerodynamic diameter of less than 2.5 µm, have especially been identified to cause health issues and lung cancer [6, 7].…”

Section: Introductionmentioning

confidence: 99%

Opportunities for Low‐Cost Particulate Matter Sensors in Filter Emission Measurements

2018

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Commercial low-cost sensors for particulate matter measurements are a fast growing market and find many applications in the particulate matter (PM) immission characterization in the environment. This application includes uncontrolled factors such as humidity, making the devices more prone to errors. These factors are controllable in closed emission control applications, turning these affordable sensors into potential monitoring devices for exhaust concentrations. Time-resolved PM emissions of a surface filter were measured at various concentration levels. The suitability and limitations of a SDS011 PM2.5 low-cost sensor were evaluated by comparing its PM readings to a welas 2100 sensor by Palas . Experimental setup and results are presented and further discussed in this paper.

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The impact of PM2.5 on asthma emergency department visits: a systematic review and meta-analysis

Cited by 196 publications

References 42 publications

Effect of exposure to ambient PM2.5 pollution on the risk of respiratory tract diseases: a meta-analysis of cohort studies

Effect of exposure to ambient PM2.5 pollution on the risk of respiratory tract diseases: a meta-analysis of cohort studies

The inflammatory potential of diet impacts the association between air pollution and childhood asthma

Opportunities for Low‐Cost Particulate Matter Sensors in Filter Emission Measurements

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