The Impact of Nutritional Status on the Outcome of Lung Volume Reduction Surgery

Variations of Inflammatory Mediators and α1-Antitrypsin Levels after Lung Volume Reduction Surgery for Emphysema

“…Moreover, by allowing re-expansion of compressed lung tissue and airways, it recruits new air spaces and auxiliary alveolar microcircles and favors better gas exchange and oxygen tissue availability. All these changes, together with the elimination of sites where inflammatory mediators are chronically produced and antiproteases are consumed, can induce a reduction of local and systemic effects of emphysema, with decrement of energy expenditure, restoration of body composition, and normalization of hormonal profile, contributing to improved pulmonary function and systemic complications, possibly slowing disease progression and reversing the respiratory cachexia (41)(42)(43)(44)(45)(46)(47)(48)(49)(50).…”

Nutritional depletion in relation to mortality in patients with chronic respiratory insufficiency treated with long-term oxygen therapy

“…Despite that, the condition is still under-diagnosed and under-treated [9]. However, tremendous efforts are being made towards a better understanding of different prognostic factors in COPD [8,[10][11][12], and new therapies with the goal of improving the prognosis and quality of life among COPD patients are increasingly used [13,14].…”

“…BMI was also found to be a significant predictor of survival in 135 nonsmoking patients with severe COPD and moderate hypoxemia [7]. Low cholesterol, another factor reflecting nutritional status, was related to the outcome of lungvolume reduction surgery in patients with emphysema [8]. However, the relationship of nutritional depletion to survival in patients with chronic respiratory insufficiency and severe hypoxemia treated with LTOT has not yet been established in detail.…”

Lung function and blood markers of nutritional status in non-COPD aging men with smoking history: A cross-sectional study

“…Our main results were as follows: (1) lower FEV 1 /FVC was linearly associated with lower RBCc, Hb, hematocrit, TP, and LDL-c after adjustments for all potential confounders; (2) FEV 1 /FVC was not associated with intake of total energy, 15 In the present study, FEV 1 /FVC was linearly associated with TP in all adjusted models, and the decrease in adjusted TP between the non-T3 and non-T1 groups was larger than that between the non-T1 and COPD groups. Nevertheless, FEV 1 /FVC was not associated with adjusted intake of total energy and nutrients, except iron.…”