This study suggests that nutritional status is closely linked with prognosis in patients with chronic respiratory insufficiency treated with domiciliary LTOT: low BMI, low plasma cholesterol and low albumin are related to worse 2-year survival in such patients.
The interwar relations between Czechoslovakia and Poland were tense for almost twenty years. Problems were caused not only by border disputes. In this situation, the interest of young Slovak intelligence in Polish culture and science began to increase in the early 1920s, which was supported by Warsaw, in its efforts to undermine the position of Prague. A well-known Slovakophile, Professor Władysław Semkowicz played an important role in supporting young Slovaks. His largest impact on Slovak-Polish relations was his patronage of visiting Slovak students at the Jagiellonian University. Semkowicz’s efforts gradually bore fruit. Many of the programme participants promoted Polish literature, art and history after their return home. This Polonophilia was not limited to the cultural sphere but also had an effect on politics. At the end of 1938, the Polish territorial claims against Slovakia severely disappointed the Polonophiles. Nevertheless, there were a number of Slovaks who kept their contacts in Polish cultural circles and continued to have pro-Polish sentiments even after the country’s defeat in September 1939.
Východiská: Reožarovanie, v kombinácii so systémovou a bio logickou liečbou, sa v súčasnosti stáva významnou opciou pre recidivujúce tumory a "in-field" sekundárne malignity, pokiaľ je chirurgia kontraindikovaná. Rozvoj zobrazovacích metód a nových ožarovacích techník v rádioterapii vytvorili priestor pre vývoj a aplikáciu presnejších postupov reožarovania s využitím rádiobio logického modelovania účinkov v režimoch hypofrakcionácie a jej extrémneho módu-stereotaxie. Normálne tkanivá a orgány po rádioterapii dokážu regenerovať a opraviť svoje poškodenie. Zvyšková tolerančná dávka orgánov v riziku (OaR) je však značne rozdielna. Pri tkanivách so skorou odpoveďou dochádza temer ku kompletnej obnove v priebehu niekoľkých mesiacov, takže druhá séria ožiarenia by mohla byť aplikovaná skoro v rovnakej výške dávky. Pre tkanivá a orgány s neskorou odpoveďou rozsah poškodenia závisí na výške celkovej dávky z ožiarenia, štruktúre funkčných subjednotiek a na intervale medzi sériami. Výrazná obnova prebieha do 3-6 mesiacov u kože, sliznice, miechy a pľúc. Iné tkanivá, napr. obličky, srdce, mechúr, disponujú len malou regeneračnou kapacitou. Cieľ: Príspevok, fokusovaný na reožarovanie, poskytuje prehľad o hodnotách kumulatívnej bio logickej efektívnej dávky (BEDcum) jednotlivých orgánov v riziku (OaR) extirpovaných z retrospektívnych štúdii, metodike stanovenia reziduálnych dávok s popisom pôvodného modelu autorov príspevku zapracovaného do výpočtu pravdepodobnosti komplikácií normálnych tkanív (normal tissue complication probability-NTCP) pri individuálnych ožarovacích plánoch reožarovania pomocou programu "BioGray" vyvinutom na pracovisku autorov. Kľúčové slová reožarovanie-kumulatívna BED-model REG pre zvyškovú tolerančnú dávku OaR pri reožarovaní-NTCP-SW BioGray Autoři deklarují, že v souvislosti s předmětem studie nemají žádné komerční zájmy. The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study. Redakční rada potvrzuje, že rukopis práce splnil ICMJE kritéria pro publikace zasílané do bi omedicínských časopisů. The Editorial Board declares that the manuscript met the ICMJE recommendation for biomedical papers. doc. RNDr. Pavol Matula, CSc. Klinika rádioterapie a onkológie Východoslovenský onkologický ústav a.s.
This paper analyzes the preparation, course and significance of one of the largest exhibitions in Central Europe at the time - the Exhibition of the East of Czechoslovakia, which was held in the summer of 1938 in Košice on the occasion of the 20th anniversary of the Czechoslovak Republic. Its goal was to approach and promote the progress that Slovakia, and especially its eastern part, has achieved in the two decades of the state's existence. The 174,000 square metre exhibition site was located in the northern part of the city on the site of what is now the Technical University. Part of the buildings constructed for the exhibition were to be handed over to the nascent Dr. Milan Rastislav Štefánik State Technical Universty after the exhibition. The exhibition was divided into five sections: 1. Czechoslovak State, 2. Slovak Country, 3. Land and People, 4. Technology and Industry, 5. Culture. The exhibition also included expositions of nearly two hundred private companies and tradesmen. In the critical situation in which the republic found itself, the exhibition was also to strengthen the patriotic spirit among the population and the determination to defend the country's independence. In terms of exhibitions, it was at a high level and pioneering in all respects.
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