The impact of endometriosis on the reproductive outcome of infertile patients

Endometriosis is not detrimental to embryo implantation in oocyte recipients

“…In addition, patients with mild endometriosis have comparable pregnancy rates when compared to those with tubal disease (13,14). Some investigators have even found no difference in pregnancy rates when comparing patients with and without endometriosis (15,16). Through an analysis of 239 first consecutive cycles in oocyte recipients, we find no difference in implantation or pregnancy rates in patients with and without endometriosis and conclude that any potential adverse effects on endometriosis must be exerted at the gamete and embryo level.…”

Is there any need for diagnostic laparoscopy in couples undergoing intracytoplasmic sperm injection for severe male-factor infertility?

“…A low fertilization rate probably related to ovulatory disorders, an altered follicular response because of disruption of ovarian blood supply or mechanical pressure, an alteration of oocyte quality resulting in a reduced implantation rate, and, finally, a toxic effect of human serum have been considered responsible for a poor outcome in IVF cycles (13,(15)(16)(17)(18). In contrast, recent reports have concluded that, regardless of its stage, endometriosis does not affect the outcome of IVF treatment (14,(19)(20)(21). The third pathology was bilateral hydrosalpinx.…”

Endometriosis

“…A study by Inoue on 2000 infertile women with mild endometriosis did not reveal any improvement in fertility with either medical or surgical therapy when compared to expectant management [ 30 ]. Other studies have demonstrated a lower pregnancy per cycle rate in patients with endometriosis compared to those free of the disease [ 31 ].…”