The how and why of a $10 optical coherence tomography system

Leahy, Martin J.; Wilson, Carol; Hogan, Josh; O’Brien, Peter; Dsouza, Roshan; Neuhaus, Kai; Bogue, D. T.; Subhash, Hrebesh M.; O’Riordan, Colm; McNamara, Paul

doi:10.1117/12.2213465

Cited by 6 publications

(7 citation statements)

References 3 publications

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“…Multiple-reference OCT (MRO) is a new type of OCT system that has a low-cost and compact configuration, with a comparable footprint to the pick-up head contained within a DVD unit [30]. The foundations of the technology are similar to first-generation time-domain OCT.…”

Section: Miniature and Low-cost Octmentioning

confidence: 99%

Optical coherence tomography in the 2020s—outside the eye clinic

Chopra

Wagner

Keane

2020

Eye

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Section: Miniature and Low-cost Octmentioning

confidence: 99%

Optical coherence tomography in the 2020s—outside the eye clinic

Chopra

Wagner

Keane

2020

Eye

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“…E Q -T A R G E T ; t e m p : i n t r a l i n k -; e 0 0 1 ; 6 3 ; 2 7 6 SNR ¼ 20 log 10 A max σ noise ;…”

Section: Multiple Reference Optical Coherence Tomography Processingunclassified

“…[7][8][9] Hence, this technology has the potential to produce a fully functional OCT system (excluding processing and display) with a bill of materials of approximately $10. 10 Furthermore, we expect MR-OCT devices to be available before photonic integrated circuit-based devices reach their full potential.…”

Section: Introductionmentioning

confidence: 99%

Development of a first-generation miniature multiple reference optical coherence tomography imaging device

McNamara

Dsouza

O’Riordan³

et al. 2016

J. Biomed. Opt

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Multiple reference optical coherence tomography (MR-OCT) is a technology ideally suited to low-cost, compact OCT imaging. This modality is an extension of time-domain OCT with the addition of a partial mirror in front of the reference mirror. This enables extended, simultaneous depth scanning with the relatively short scan range of a miniature voice coil motor on which the scanning mirror is mounted. This work details early stage development of the first iteration of a miniature MR-OCT device. This iteration utilizes a fiber-coupled input from an off-board superluminescent diode. The dimensions of the module are 40 × 57 ?? mm . Off-the-shelf miniature optical components, voice coil motors, and photodetectors are used, with the complexity of design depending on the specific application. The photonic module can be configured as either polarized or nonpolarized and can include balanced detection. The results shown in this work are from the nonpolarized device. The system was characterized through measurement of the input spectrum, axial resolution, and signal-to-noise ratio. Typical B-scans of static and in vivo samples are shown, which illustrate the potential applications for such a technology.

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“…Previous reports demonstrated the development of a compact platform within a handheld low-coherence interferometry (LCI) system, 20 and a multiple reference (MR) OCT system. [21][22][23] The handheld LCI system used for in vivo ear imaging was based on a linear OCT approach, 20 and the overall cost to develop this system was significantly lower than most other FD-OCT systems. MR-OCT, another low-cost OCT approach, was developed based on a partial mirror and actuator configuration, generating a recirculating optical delay line.…”

Section: Introductionmentioning

confidence: 99%

“…The cost of the MR-OCT engine is anticipated to be similar to that of a CD/DVD unit (USD10). 22 Despite the low-cost and portability of these units, they represent only one part of a complete OCT system, which also includes other optical hardware, a processing computer and software, and a beam delivery system such as a handheld probe.…”

Section: Introductionmentioning

confidence: 99%

Economical and compact briefcase spectral-domain optical coherence tomography system for primary care and point-of-care applications

et al. 2018

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Development of low-cost and portable optical coherence tomography (OCT) systems is of global interest in the OCT research community. Such systems enable utility broadly throughout a clinical facility, or in remote areas that often lack clinical infrastructure. We report the development and validation of a low-cost, portable briefcase spectral-domain optical coherence tomography (SD-OCT) system for point-of-care diagnostics in primary care centers and/or in remote settings. The self-contained briefcase OCT contains all associated optical hardware, including light source, spectrometer, hand-held probe, and a laptop. Additionally, this system utilizes unique real-time mosaicking of surface video images that are synchronized with rapid A-scan acquisition to eliminate the need for lateral scanning hardware, and enable the construction of cross-sectional B-mode images over extended lateral distances. The entire briefcase system weighs 9 kg and costs ∼USD8000 using off-the-shelf components. System performance was validated by acquiring images of in vivo human skin on the fingertip, palm, and nail fold. The efficiency, portability, and low-cost enable accessibility and utility in primary care centers and low-resource settings.

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The how and why of a $10 optical coherence tomography system

Cited by 6 publications

References 3 publications

Optical coherence tomography in the 2020s—outside the eye clinic

Optical coherence tomography in the 2020s—outside the eye clinic

Development of a first-generation miniature multiple reference optical coherence tomography imaging device

Economical and compact briefcase spectral-domain optical coherence tomography system for primary care and point-of-care applications

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