The HLA-D determinants

Kaakinen, Aulikki; Helgesen, Astri; Nousiainen, Helena; Solheim, Bjarte G.; Thorsby, E.

doi:10.1007/bf01575660

Cited by 31 publications

(1 citation statement)

References 9 publications

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“…Some of the results of the HLA-A, B, C, and DR typing of the 33 seropositive and the 15 seronegative RA patients are given in Table 1. No strong association was found between any of the HLA-A, B, and C antigens and RA, except for B15 and Cw3, which may be explained by nonrandom associations to D/DRw4 (13). The frequencies of the HLA-A1, A2, Bw35, B37, B40, and Cw3 antigens differed somewhat between the seropositive and the seronegative group, and the A I , Aw 19, B8, and B 12 antigens differed in frequency between female and male RA patients, but none of the differences were significant when corrected for number of comparisons.…”

Section: Resultsmentioning

confidence: 76%

Hla antigens and rheumatoid arthritis association between hla‐drw4 positivity and igm rheumatoid factor production

Dobloug¹,

Førre²,

Kåss³

et al. 1980

Arthritis & Rheumatism

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110

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Section: Resultsmentioning

confidence: 76%

Hla antigens and rheumatoid arthritis association between hla‐drw4 positivity and igm rheumatoid factor production

Dobloug¹,

Førre²,

Kåss³

et al. 1980

Arthritis & Rheumatism

Self Cite

110

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HLA antigens in malignant melanoma

Bergholtz

Brennhovd

Klepp

et al. 1977

Cancer

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Analysis of the HLA-ABC linkage disequilibrium: Decreasing strength of gametic association with increasing map distance

et al. 1978

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1242 HLA-ABC haplotypes of the North German population (Hambrug) as deduced by family analyses are described. They are in perfect agreement with recently published data by Mayr (1977) from Austria (Vienna) in all parameters tested: frequency of the single HLA-alleles, haplotype distribution and linkage disequilibrium values. Gametic association studies revealed that 69.4% of the B and C genes (map distance 0.2cM) 36.9% of the A and C genes (0.6 cM), but only 23.2% of the A and B genes (0.8 cM) were significantly more often combined than expected due to their frequencies. From these findings it seems likely that the linkage disequilibrium within the MHC is rather due to a short evolutionary period than to selective forces. Some observations as to the most common European haplotype A1,B8 are discussed.

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The HLA-D determinants

Cited by 31 publications

References 9 publications

Hla antigens and rheumatoid arthritis association between hla‐drw4 positivity and igm rheumatoid factor production

Hla antigens and rheumatoid arthritis association between hla‐drw4 positivity and igm rheumatoid factor production

HLA antigens in malignant melanoma

Analysis of the HLA-ABC linkage disequilibrium: Decreasing strength of gametic association with increasing map distance

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