The History of Sclerosing Foams

Abstract

The use of foamed sclerosing agents in therapy of large or small varicose veins is not new. It started as early as 1939 and has continuously been improved in the past decades.

Ethanol Sclerotherapy of Superficial Venous Malformation: A New Procedure

“…The sclerosing foam is composed of gas and a liquid sclerosant [31,32], and its injection causes blood displacement in the vessel to be treated. The great advantages of foam over liquid sclerosant are a more uniform distribution on the endothelial surface and a prolonged local permanence time, enhancing the endothelial damage [33,34].…”

Applications of Polidocanol in Varicose Vein Treatment Assisted by Exposure to Nd:YAG Laser Radiation

“…Two ml of POL (Aetoxysclerol® tamponné/lauromacrogol 400 (Kreussler Pharma, Germany) were used at 0.3% and 8 ml of air. Pumping and passing from one syringe to the other 15 times, produces stable micro-foam following the Tessari technique (Cavezzi et al, 2002;Frullini, 2000;Hamel-Desnos et al, 2003;Tessari, 2001;Tessari et al 2001;Wollmann, 2004). The resulting foam is rich in nitrogen, with an irregular bubble size and a highly internal cohesion (Redondo and Cabrera , 2005).…”

Sklerosierungstherapie der Varikose

“…1 9 Auf ge schäum tes Skle ro sie rungs mit tel in ei ner Va ri ze, so no gra phische Dar stel lung schäum ten Skle ro sie rungs mit teln be richtet [8,19,45,59,75,76]. In den letz ten Jahren wur de er neut stär ker über die Sklero sie rung mit Schaum dis ku tiert [36,48,57], vor al lem bei der The ra pie grö ße rer Va ri zen.…”