The Histological Spectrum of Myxoma, Myxofibroma /Fibromyxoma and Odontogenic Fibroma- “A Chicken And Egg Situation”

Solomon, Monica Charlotte

doi:10.9790/0853-0120305

Cited by 8 publications

(10 citation statements)

References 12 publications

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“…The given epicentres for pathogenesis are still a dilemma for origin and yet to be proved because some studies signify that OM stroma has no resemblance to dental follicle and it may be a dual fibroblast-histiocytic origin 15. This duality arises because of the hypothetical origin of fibroblasts to produce mucopolysaccharides which mimic myxoid tumours histopathologically 16. This theory is still uncertain whether a familiar situation of ‘chicken and egg’ for histogenesis of these tumours.…”

Section: Discussionmentioning

confidence: 99%

Central odontogenic fibromyxoma of mandible: an aggressive odontogenic pathology

Bahl¹,

Raju²,

Shah

et al. 2016

BMJ Case Reports

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Myxoma of the jaws which was first described by Thoma and Goldman in 1947 is a rare neoplasm and its rate of prevalence and incidence is not available. Myxoma term, according to 1992 WHO classification, is used along with odontogenic myxoma (OM) and myxofibroma. There are two forms of myxomas or fibromyxomas that are recognised in head and neck region: one is derived from the facial skeleton and the other is derived from the soft tissue. Most of the OM are located intraosseously, but peripheral ones are also recognised. OM behaves differently from myxomatous tumours of long bones, which recur more often and may transform into malignancy. A majority of these lesions occur between 2nd and 4th decade. In the pathogenesis of OM, dental papilla, dental follicle and periodontal ligament tissues have been implicated as possible 'germ centres'. This case describes an uncommon finding of central odontogenic fibromyxoma, throwing light on its epidemiology, clinical, histopathology, molecular and treatment aspects.

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Section: Discussionmentioning

confidence: 99%

Central odontogenic fibromyxoma of mandible: an aggressive odontogenic pathology

Bahl¹,

Raju²,

Shah

et al. 2016

BMJ Case Reports

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“…In contrary, central odontogenic myxomas are generally nonencapsulated tumors with infiltrative capacity into the adjacent medullary bone. [ 3 ] Histologically, myxomas show delicate fibrous to loose mucoid stroma, this is due to the presence of undifferentiated mesenchymal cells showing fibroblastic differentiation. [ 2 3 4 5 ] When dense collagenous stroma is evident the term-fibro myxoma/myxofibroma can be used interchangeably.…”

Section: Introductionmentioning

confidence: 99%

“…[ 3 ] Histologically, myxomas show delicate fibrous to loose mucoid stroma, this is due to the presence of undifferentiated mesenchymal cells showing fibroblastic differentiation. [ 2 3 4 5 ] When dense collagenous stroma is evident the term-fibro myxoma/myxofibroma can be used interchangeably. [ 3 ] Due to this dual pattern, the odontogenic myxoma is believed to be a continuum of odontogenic fibroma.…”

Section: Introductionmentioning

confidence: 99%

“…[ 2 3 4 5 ] When dense collagenous stroma is evident the term-fibro myxoma/myxofibroma can be used interchangeably. [ 3 ] Due to this dual pattern, the odontogenic myxoma is believed to be a continuum of odontogenic fibroma. [ 3 ] The present report highlights a rare entity of odontogenic tumors, i.e., central odontogenic myxoma in a 43-year-old male patient who presented with painless swelling over left posterior cheek region.…”

Section: Introductionmentioning

confidence: 99%

“…[ 3 ] Due to this dual pattern, the odontogenic myxoma is believed to be a continuum of odontogenic fibroma. [ 3 ] The present report highlights a rare entity of odontogenic tumors, i.e., central odontogenic myxoma in a 43-year-old male patient who presented with painless swelling over left posterior cheek region. Based on clinical, radiological and histopathological findings, the diagnosis of odontogenic myxoma was made.…”

Section: Introductionmentioning

confidence: 99%

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Odontogenic myxoma: A causality dilemma – Report of a nonpareil case and review of literature

Swamy¹,

Naag

Bahl³

et al. 2018

J Oral Maxillofac Pathol

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Odontogenic myxoma is a benign locally aggressive neoplasm with a sparse prevalence and incertitude histogenesis. They constitute 3%–6% of odontogenic tumors in gnathic bones. It is ubiquitously seen between vicenarian to early quadragenarian group with female proclivity and fondness to the mandibular jaws. They are silent lesions clinically and show myxoid stroma amidst fibrous background. This report highlights central odontogenic myxoma in a 43-year-old male patient and focuses on concepts, differential diagnosis, molecular concepts and treatment aspect.

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Odontogenic Myxoma: A 23-Year Retrospective Series of 38 Cases

Banasser

Bawazir

Islam

et al. 2020

Head and Neck Pathol

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The Histological Spectrum of Myxoma, Myxofibroma /Fibromyxoma and Odontogenic Fibroma- “A Chicken And Egg Situation”

Cited by 8 publications

References 12 publications

Central odontogenic fibromyxoma of mandible: an aggressive odontogenic pathology

Central odontogenic fibromyxoma of mandible: an aggressive odontogenic pathology

Odontogenic myxoma: A causality dilemma – Report of a nonpareil case and review of literature

Odontogenic Myxoma: A 23-Year Retrospective Series of 38 Cases

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