The emergence of India as a blossoming market for nutraceutical supplements: An overview

Fernandes, Swapnil Dylan; Narayana, R. Charyulu; Vadakkepushpakath, Anoop Narayanan

doi:10.1016/j.tifs.2019.02.017

Cited by 10 publications

(10 citation statements)

References 2 publications

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“…Recent years have witnessed extensive research into the role of nutraceuticals in metabolic diseases, focusing on their oxi-metabolic effects. According to market analysis and the available literature, many nutraceutical products are well-formulated to prevent and manage various health conditions, including diabetes, obesity, and hypertension [ 88 ]. This review specifically addresses nutraceutical formulations aimed at improving cardiometabolic disorders and mitigating oxidative stress ( Table 1 ).…”

Section: Nutraceuticals Usage In Addressing Oxidative Stress and Infl...mentioning

confidence: 99%

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Targeting Metabolic Diseases: The Role of Nutraceuticals in Modulating Oxidative Stress and Inflammation

Dama,

Shpati,

Daliu

et al. 2024

Nutrients

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The escalating prevalence of metabolic and cardiometabolic disorders, often characterized by oxidative stress and chronic inflammation, poses significant health challenges globally. As the traditional therapeutic approaches may sometimes fall short in managing these health conditions, attention is growing toward nutraceuticals worldwide; with compounds being obtained from natural sources with potential therapeutic beneficial effects being shown to potentially support and, in some cases, replace pharmacological treatments, especially for individuals who do not qualify for conventional pharmacological treatments. This review delves into the burgeoning field of nutraceutical-based pharmacological modulation as a promising strategy for attenuating oxidative stress and inflammation in metabolic and cardiometabolic disorders. Drawing from an extensive body of research, the review showcases various nutraceutical agents, such as polyphenols, omega-3 fatty acids, and antioxidants, which exhibit antioxidative and anti-inflammatory properties. All these can be classified as novel nutraceutical-based drugs that are capable of regulating pathways to mitigate oxidative-stress- and inflammation-associated metabolic diseases. By exploring the mechanisms through which nutraceuticals interact with oxidative stress pathways and immune responses, this review highlights their potential to restore redox balance and temper chronic inflammation. Additionally, the challenges and prospects of nutraceutical-based interventions are discussed, encompassing bioavailability enhancement, personalized treatment approaches, and clinical translation. Through a comprehensive analysis of the latest scientific reports, this article underscores the potential of nutraceutical-based pharmacological treatment modulation as a novel avenue to fight oxidative stress and inflammation in the complex landscape of metabolic disorders, particularly accentuating their impact on cardiovascular health.

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Section: Nutraceuticals Usage In Addressing Oxidative Stress and Infl...mentioning

confidence: 99%

“…The formulations have an important role in addition to drug interactions in poly-medication treatments. Strict regulation is essential to curb their uncontrolled use and prevent undesirable side effects [ 88 ].…”

Section: Nutraceuticals As Novel Drug Targetsmentioning

confidence: 99%

Targeting Metabolic Diseases: The Role of Nutraceuticals in Modulating Oxidative Stress and Inflammation

Dama,

Shpati,

Daliu

et al. 2024

Nutrients

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“…Nutraceuticals are a powerful resource that can be used ʺbeyond the diet but before the drugsʺ to prevent and treat pathological conditions as ʺpharma-foodsʺ [115]. In recent years, the focus of nutraceuticals has shifted to efficacy, safety, epidemiology, and toxicity [116,117].…”

Section: Nutraceuticalsmentioning

confidence: 99%

Nutraceutical Benefits for Bone Health: Role in Osteoporosis Prevention

Roseti,

Borciani,

Grassi

et al. 2023

Preprint

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Osteoporosis is characterized by low bone mass and structural deterioration of bone tissue with increased risk of fracture. The population that is most at risk for primary osteoporosis in-cludes post-menopausal women. Among different approaches, nutraceuticals are increasingly popular in developed countries since can contribute to bone health and can delay the onset of pathological bone loss. Our review covers three main aspects. Firstly, we discuss the current state of the two con-ditions, osteopenia, and osteoporosis. Secondly, we focus on the latest developments in natural Nutraceuticals and their effectiveness in reducing bone loss. Finally, we conduct a Strengths, Weaknesses, Opportunities, and Threats (SWOT) analysis to examine the pros and cons of Nutraceuticals assumption. Nutraceuticals hold great promise, but we must address challenges such as regulatory control and experimental evidence to fully realize their potential. Other challenges include identifying the source of raw materials, ensuring the purity of the compound, avoiding contamination or the presence of other active compounds, maintaining product quality, and preventing interactions with other elements or drugs. By addressing these challenges, the scientific community can ensure more reliable indica-tions for the use of Nutraceuticals and help people lead healthier lives.

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“…There is a plethora of benefits that nutraceuticals have provided, including their promising results in the prevention and treatment of complicated diseases. However, there is a need of administration and prescription of nutraceuticals and they should be strictly regulated in order to prevent their uncontrollable use and side effects [ 3 ]. Several researchers have studied drug compound-based nutraceuticals to improve the efficacy as well as bioavailability.…”

Section: Introductionmentioning

confidence: 99%

A Comprehensive Review on Nutraceuticals: Therapy Support and Formulation Challenges

et al. 2022

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Nutraceuticals are the nourishing components (hybrid of nutrition and pharmaceuticals) that are biologically active and possess capability for maintaining optimal health and benefits. These products play a significant role in human health care and its endurance, most importantly for the future therapeutic development. Nutraceuticals have received recognition due to their nutritional benefits along with therapeutic effects and safety profile. Nutraceuticals are globally growing in the field of services such as health care promotion, disease reduction, etc. Various drug nutraceutical interactions have also been elaborated with various examples in this review. Several patents on nutraceuticals in agricultural applications and in various diseases have been stated in the last section of review, which confirms the exponential growth of nutraceuticals’ market value. Nutraceuticals have been used not only for nutrition but also as a support therapy for the prevention and treatment of various diseases, such as to reduce side effects of cancer chemotherapy and radiotherapy. Diverse novel nanoformulation approaches tend to overcome challenges involved in formulation development of nutraceuticals. Prior information on various interactions with drugs may help in preventing any deleterious effects of nutraceuticals products. Nanotechnology also leads to the generation of micronized dietary products and other nutraceutical supplements with improved health benefits. In this review article, the latest key findings (clinical studies) on nutraceuticals that show the therapeutic action of nutraceutical’s bioactive molecules on various diseases have also been discussed.

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The emergence of India as a blossoming market for nutraceutical supplements: An overview

Cited by 10 publications

References 2 publications

Targeting Metabolic Diseases: The Role of Nutraceuticals in Modulating Oxidative Stress and Inflammation

Targeting Metabolic Diseases: The Role of Nutraceuticals in Modulating Oxidative Stress and Inflammation

Nutraceutical Benefits for Bone Health: Role in Osteoporosis Prevention

A Comprehensive Review on Nutraceuticals: Therapy Support and Formulation Challenges

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