The Effects of Two Lactobacillus plantarum Strains on Rat Lipid Metabolism Receiving a High Fat Diet

Abstract

The aim of our study was to evaluate the effects of the different probiotic strains, Lactobacillus plantarum LS/07 and Lactobacillus plantarum Biocenol LP96, on lipid metabolism and body weight in rats fed a high fat diet. Compared with the high fat diet group, the results showed that Lactobacillus plantarum LS/07 reduced serum cholesterol and LDL cholesterol, but Lactobacillus plantarum Biocenol LP96 decreased triglycerides and VLDL, while there was no change in the serum HDL level and liver lipids. Both probiotic strains lowered total bile acids in serum. Our strains have no significant change in body weight, gain weight, and body fat. These findings indicate that the effect of lactobacilli on lipid metabolism may differ among strains and that the Lactobacillus plantarum LS/07 and Lactobacillus plantarum Biocenol LP96 can be used to improve lipid profile and can contribute to a healthier bowel microbial balance.

Chemical composition and hypocholesterolemic effect of milk kefir and water kefir in Wistar rats

“…Although values for triglycerides [27,32] and glucose [25] decreased in some studies on probiotic microorganisms, we did not experience this in our study.…”

Effects of Lactic Acid Bacteria‐Fermented Soymilk on Isoflavone Metabolites and Short‐Chain Fatty Acids Excretion and Their Modulating Effects on Gut Microbiota

“…Lactobacillus rhamnosus administration alone caused a significant reduction in the β-glucuronidase activity in the first week, but the enzyme activity went back to normal in the fourth week. While a previous study also reported that probiotics, L. rhamnosus GG and L. acidophilus, could inhibit the β-glucuronidase activity in the caecum of both lean and obese animals (Salaj et al, 2013), we observed only temporary changes. Furthermore, we introduced a consistent antibiotics intervention to mimic the antibiotics treatment in daily soymilk or fermented soymilk consumption.…”

Possible Kefir Biological Effects: 4: Effect of Kefir Beverage on The Histopathological and Macroscopical Changes in Adipose Tissue of High Fat-Fed STZ- Induced Diabetic Male Wistar Rat

“…However, some studies observed that rat body weight gain was similar in both groups (control and kefir); No significant differences were found (Elena et al, 2007;Sahin and Yardimci, 2009;Ataşoğlu et al, 2010;Kızak and Çelik, 2012;Aliakbarpour et al, 2013;Salaj et al, 2013;Piccolo et al, 2015).…”