The Effects of Transcutaneous and Intraoral Low-Level Laser Therapy After Extraction of Lower Third Molars: A Randomized Single Blind, Placebo Controlled Dual-Center Study

Kahraman, Sibel; Çetiner, Sedat; Strauss, Robert A.

doi:10.1089/pho.2016.4252

Cited by 35 publications

(55 citation statements)

References 21 publications

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“…Other studies exhibited that LLLT produced a positive effect on reducing the degree of pain in patients who underwent surgical interventions. [10][11][12][13][14][15][16][17][18] Bjordal et al 39 in a systematic review demonstrated that adequate doses of photoradiation can significantly alleviate acute inflammatory pain by suppressing the levels of biochemical markers.…”

Section: Discussionmentioning

confidence: 99%

“…Some studies demonstrated the beneficial effects of laser therapy on reducing pain, swelling and trismus after the surgical removal of impacted lower third molars. [10][11][12][13][14][15][16][17][18] Others revealed that the application of LLLT enhanced bone healing and mineralization in the sockets of rats exposed to diode laser radiation. [19][20][21][22][23] However, some studies found no additional benefits of using low-level lasers over the placebo in several conditions such as releasing pain after the extraction of primary 24 and permanent 25 teeth, reducing pain and swelling following third molar surgery, [26][27][28] improving pulp tissue healing after direct pulp capping in dogs, 29 and attenuating chronic orofacial pain in patients with temporomandibular dysfunction (TMD).…”

Section: Introductionmentioning

confidence: 99%

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Effectiveness of Low-Level Laser Irradiation in Reducing Pain and Accelerating Socket Healing After Undisturbed Tooth Extraction

et al. 2020

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Introduction: This study aimed to determine the effect of low-level laser therapy (LLLT) on reducing complications following tooth extraction. Methods: This randomized clinical trial consisted of 40 subjects who underwent lower molar extraction. The patients were randomly assigned to 4 groups. Group 1 was irradiated with a 660 nm laser (200 mW, 30 seconds radiation to lingual, buccal and occlusal surfaces of the socket, 6 J/area). In group 2, an 810 nm laser was applied similar to group 1. In group 3, a combination of 660 and 810 nm lasers was used. The patients in group 4 served as a placebo group. LLLT was performed after 0.5-1 hour of extraction and 2 days later. The participants were asked to record pain degree using a visual analogue scale (VAS) over 7 days. The amount of wound healing was evaluated on the third and seventh days. Results: There was no significant difference in pain scores among the groups at any of the assessment intervals (P>0.05). The between-group differences in wound healing scores were small and insignificant (P>0.05). Conclusion: LLLT with 660 nm or 810 nm lasers or their combination had no greater effect than the placebo laser for reducing the complications of tooth extraction.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effectiveness of Low-Level Laser Irradiation in Reducing Pain and Accelerating Socket Healing After Undisturbed Tooth Extraction

et al. 2020

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“…In all these studies, the third molar was the extracted tooth except in one study conducted on premolar's extraction sockets. 23 PBM effectively reduced post extraction pain as shown in 16 studies 5,6,13,[15][16][17][18][19][24][25][26][27][28][29][30][31] compared with placebo. In these studies, wavelengths ranged from 650 to 980 nm.…”

Section: Study Selectionmentioning

confidence: 77%

Photobiomodulation in Oral Surgery: A Review

Hosseinpour

Tunér

Fekrazad

2019

Photobiomodulation, Photomedicine, and Laser Surgery

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Objective: This article presents a review of current data on the applications of photobiomodulation (PBM) in the field of oral and maxillofacial surgery (OMFS), to guide future research. Background data: Photobiomodulation therapy (PBMT) has been reported to be effective for various postoperative conditions, including pain relief, improvement of mastication, neurosensory recovery, and wound healing. There is a need for identifying the therapeutic irradiation windows for these conditions, based upon the available literature. Materials and methods: All original articles related to PBM for oral surgery in MEDLINE (NCBI PubMed and PMC), EMBASE, Scopus, Cochrane library, Web of Science, and Google Scholar were reviewed until December 2018. Results: Forty-six clinical trials were included in this study. These trials were categorized into three different types of PBM applications. After reviewing all these studies, the most effective physical properties for PBM pain reduction after tooth extraction were as follows: wavelength 650-980 nm; power 4-300 mW; and energy density 3-85.7 J/cm 2. PBMT at 660-910 nm with 4-500 mW power and 2-480 J/cm 2 energy density was effective for decreasing facial swelling. At the same wavelength and power range with 4-106 J/cm 2 energy density, PBM was effective for alleviating trismus after tooth extraction. Conclusions: Most papers suggested that PBM seemed to be effective in reducing pain, swelling, and trismus after third molar tooth extraction, neurosensory and nerve recovery after mandibular ramus osteotomy. The heterogeneity of the standardization regarding the parameters of laser calls for caution in interpretation of these results. However, this evidence-based review regarding the best protocols for OMFS applications can be beneficial for both future research and clinical applications.

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“…As previously mentioned, third molar extractions are among the most frequent oral surgery procedures, which is also commonly associated with postoperative pain, resulting in impaired quality of life during the postoperative course. In the literature, there is still a lack of evidence regarding PBMT effectiveness in reducing third molar extraction postoperative pain, where previous studies presented positive and others no difference compared to a control group ( 20 - 22 ). Also, there are no standardized protocols of PBMT considering the number of sessions, administration mode, and wavelengths ( 23 ).…”

Section: Discussionmentioning

confidence: 99%

Photobiomodulation therapy reduces postoperative pain after third molar extractions: A randomized clinical trial

Isolan

Kinalski²,

Leão³

et al. 2021

Med Oral

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Background To assess the efficacy of PBMT on reducing postoperative pain scores in patients submitted to third molar extractions. Material and Methods A randomized controlled trial (ReBEC:RBR-94BCKZ) was designed according to the SPIRIT and followed the CONSORT. Patients were randomly allocated according to control or PBMT groups. PBMT consisted of the application of GaAlAs laser (808nm;50mW) applied in six points (1.23 min;11 J/cm2) after extraction. Pain scores were assessed using the Visual Analogue Scale (VAS) in millimeters evaluated after 6 (T6), 24 (T24), and 48 (T48) hours. The Wilcoxon Mann–Whitney test was used to check for possible associations between VAS scores and treatment groups. Results A total of 101 third molar extractions were performed in 44 patients. The mean age was 28 years old(SD±11.54). Comparing control and intervention, PBMT group showed a significant effect on the reduction of postoperative pain at T6(mean VAS=0.9; C.I:0.63–1.16) compared to control (mean VAS=2.5;C.I:2.1–2.88)( p <0.001). The same statistically significant effect on the reduction of postoperative pain was observed at T24 (PBMT mean VAS=0.72;C.I:0.51–0.93; control mean VAS=2.86;C.I:2.40–3.31; p <0.001) and T48 (PBMT mean VAS=0.64;C.I:0.36–0.92; control mean VAS=2.86;C.I:2.37–3.34; p <0.001). Conclusions PBMT significantly reduce the postoperative pain scores when assessed 6, 24, and 48 hours after third molar extractions. Key words: Controlled clinical trial, gallium aluminium arsenide lasers, third molar.

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The Effects of Transcutaneous and Intraoral Low-Level Laser Therapy After Extraction of Lower Third Molars: A Randomized Single Blind, Placebo Controlled Dual-Center Study

Cited by 35 publications

References 21 publications

Effectiveness of Low-Level Laser Irradiation in Reducing Pain and Accelerating Socket Healing After Undisturbed Tooth Extraction

Effectiveness of Low-Level Laser Irradiation in Reducing Pain and Accelerating Socket Healing After Undisturbed Tooth Extraction

Photobiomodulation in Oral Surgery: A Review

Photobiomodulation therapy reduces postoperative pain after third molar extractions: A randomized clinical trial

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