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2004
DOI: 10.1016/j.toxlet.2004.03.010
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The effects of tobacco smoke on plasma alpha- and gamma-tocopherol levels in passive and active cigarette smokers

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Cited by 29 publications
(21 citation statements)
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References 34 publications
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“…Pups exposed to the P2 protocol presented oxidative damage in the brain, which was verified by the increase in lipid peroxidation, inhibition of -ALA-D activity, marked reduction in non-enzymatic antioxidant parameters (NPSH and ascorbic acid), and inhibition of SOD and catalase activities. These results are in accordance with previous data demonstrating that oxidative stress caused by cigarette smoke exposure causes a decrease in the concentration of some antioxidants (Sobczak et al, 2004;Avti et al, 2006).…”
Section: Discussionsupporting
confidence: 93%
“…Pups exposed to the P2 protocol presented oxidative damage in the brain, which was verified by the increase in lipid peroxidation, inhibition of -ALA-D activity, marked reduction in non-enzymatic antioxidant parameters (NPSH and ascorbic acid), and inhibition of SOD and catalase activities. These results are in accordance with previous data demonstrating that oxidative stress caused by cigarette smoke exposure causes a decrease in the concentration of some antioxidants (Sobczak et al, 2004;Avti et al, 2006).…”
Section: Discussionsupporting
confidence: 93%
“…In fact, the influence of tobacco smoking on the level of α-tocopherol has been well documented, and divergent data exist concerning γ-tocopherol only 33. We believe that the reason for discrepancy between our findings and the results reported in other studies may be related to the assessment of smoking habit based on a questionnaire only and not on more objective methods, such as assessment of the cotinine concentration in urine/plasma.…”
Section: Discussioncontrasting
confidence: 94%
“…28 Cigarette smoking leads to mesangial cell proliferation as well as induction of extracellular matrix proteins and generation of ROS. [13][14][15][16][17][18][19][20][21] The use of calcineurin-free regimens consists of a combination of sirolimus and mycophenolate mofetil, but these agents alone or in combination can result in increased proteinuria in organ transplant recipients. 29 -37 PTE cells are an important component of renal tissue and play a major role in nephron damage.…”
Section: Discussionmentioning
confidence: 99%