The Effects of Probiotics on Body Weight and Biomarkers of Animal

Karimi, Golgis; Jamaluddin, Rosita; Parvaneh, Kolsoom

doi:10.3923/pjn.2013.793.799

Cited by 5 publications

(2 citation statements)

References 30 publications

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“…Recent clinical and experimental studies indicated that probiotic supplementation greatly differ in the metabolism of actions and efficacy. There are several mechanisms by which the bacterial strains elicit their function [4,18,19,28]. Most of the previous studies have evaluated the impact of probiotics during HFD feeding (preventive effect) and revealed that probiotic effects are strain-dependent [20,21].…”

Section: Discussionmentioning

confidence: 99%

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Single-species versus dual-species probiotic supplementation as an emerging therapeutic strategy for obesity

Karimi

Jamaluddin

Mohtarrudin

et al. 2017

Nutrition, Metabolism and Cardiovascular Diseases

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Section: Discussionmentioning

confidence: 99%

“…Accumulating evidence indicates an association between gut microbiota and obesity as well as related metabolic disorders [3,4]. The effect of gut microbiota on obesity lies on a wide spectrum from the improvement of lipid profiles [5] and inflammatory biomarkers [6] to its effect of reducing body weight [7] and fat mass [8].…”

Section: Introductionmentioning

confidence: 99%

Single-species versus dual-species probiotic supplementation as an emerging therapeutic strategy for obesity

Karimi

Jamaluddin

Mohtarrudin

et al. 2017

Nutrition, Metabolism and Cardiovascular Diseases

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The effects of prebiotic, probiotic, and synbiotic supplementation on blood parameters of renal function: A systematic review and meta-analysis of clinical trials

Firouzi

Haghighatdoost

2018

Nutrition

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Oral Probiotic Bifidobacterium Longum Supplementation Improves Metabolic Parameters and Alters the Expression of the Renin-Angiotensin System in Obese Mice Liver

Machado

Oliveira

Lelis

et al. 2020

Biological Research For Nursing

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Background: Obesity and non-alcoholic fatty liver disease (NAFLD) have been increasing at an alarming rate worldwide. Bifidobacterium longum (BL), a common member of the human gut microbiota, has important health benefits through several mechanisms. Objectives: We evaluated the BL supplementation effects on body metabolism and renin-angiotensin components hepatic expression in mice fed a high-fat diet. Methods: Thirty-two male mice were divided into four groups: standard diet + placebo (ST), standard diet + Bifidobacterium longum (ST + BL), high-fat diet + placebo (HFD) and high-fat diet + Bifidobacterium longum (HFD + BL). Following the obesity induction period, the ST + BL and HFD + BL groups were supplemented with Bifidobacterium longum for 4 weeks. Then, body, biochemical, histological and molecular parameters were evaluated. Results: HFD + BL mice had a significant decrease in adipose tissue mass and blood glucose levels, as well as a significant reduction in blood glucose during an intraperitoneal glucose tolerance test. The treatment also resulted in reduced levels of total cholesterol and hepatic fat accumulation. Moreover, we observed an increase in angiotensin converting enzyme 2 (ACE2) and Mas receptor (MASR) expression levels in BL-treated obese mice. Conclusions: These data demonstrate that BL may have the potential to prevent obesity and NAFLD by modulating the mRNA expression of renin-angiotensin system components.

show abstract

The Effects of Probiotics on Body Weight and Biomarkers of Animal

Cited by 5 publications

References 30 publications

Single-species versus dual-species probiotic supplementation as an emerging therapeutic strategy for obesity

Single-species versus dual-species probiotic supplementation as an emerging therapeutic strategy for obesity

The effects of prebiotic, probiotic, and synbiotic supplementation on blood parameters of renal function: A systematic review and meta-analysis of clinical trials

Oral Probiotic Bifidobacterium Longum Supplementation Improves Metabolic Parameters and Alters the Expression of the Renin-Angiotensin System in Obese Mice Liver

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