The effects of prebiotic, probiotic, and synbiotic supplementation on blood parameters of renal function: A systematic review and meta-analysis of clinical trials

Firouzi, Somayyeh; Haghighatdoost, Fahimeh

doi:10.1016/j.nut.2018.01.007

Cited by 35 publications

(25 citation statements)

References 39 publications

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“…Because the microbiota structure/composition is comparable to a fingerprint and there are different levels and types of dysbiosis, the correct use of probiotics/prebiotics/synbiotics should consider prior knowledge of the type of dysbiosis to proceed with a targeted treatment for the patient. The positive effect of probiotic, prebiotic, or synbiotic treatment could depend on the individual’s pathology, as indicated by systematic reviews considering different milieus [131,132]. Results of studies conducted thus far on pro/prebiotics are very variable and reflect the diversity of the tested probiotic strains, as well as the diversity of the populations examined.…”

Section: Probiotics Prebiotics and Synbioticsmentioning

confidence: 99%

Rebuilding the Gut Microbiota Ecosystem

Gagliardi

Totino

Cacciotti

et al. 2018

IJERPH

262

174

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A microbial ecosystem in which bacteria no longer live in a mutualistic association is called dysbiotic. Gut microbiota dysbiosis is a condition related with the pathogenesis of intestinal illnesses (irritable bowel syndrome, celiac disease, and inflammatory bowel disease) and extra-intestinal illnesses (obesity, metabolic disorder, cardiovascular syndrome, allergy, and asthma). Dysbiosis status has been related to various important pathologies, and many therapeutic strategies aimed at restoring the balance of the intestinal ecosystem have been implemented. These strategies include the administration of probiotics, prebiotics, and synbiotics; phage therapy; fecal transplantation; bacterial consortium transplantation; and a still poorly investigated approach based on predatory bacteria. This review discusses the various aspects of these strategies to counteract intestinal dysbiosis.

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Section: Probiotics Prebiotics and Synbioticsmentioning

confidence: 99%

Rebuilding the Gut Microbiota Ecosystem

Gagliardi

Totino

Cacciotti

et al. 2018

IJERPH

262

174

View full text Add to dashboard Cite

show abstract

“…It is well documented that prebiotics, probiotics and the symbiotic supplementation had resulted in the improvement of renal function. Firouzi and Haghighatdoost [127] studied renal profile of a meta-analysis of a clinical trial. They pointed out that level of glomerular filtration rate was reduced whereas the concentration of creatinine was increased in the intervention group in comparison to the placebo group and the results were non-significant.…”

Section: Prebiotics and Renal Profilementioning

confidence: 99%

Therapeutic Potential of Probiotics and Prebiotics

Gulzar¹,

Saleem²,

Rafiq³

et al. 2019

Oral Health by Using Probiotic Products

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Advancement in technology is continued as the time is passed. The biological active ingredients technology is the challenging issues for both the researchers and manufacturers. In last decade, much research has been happened about the potential health benefits of pro and prebiotic ingredients. Probiotics are the live microorganisms when given in adequate amount confer health benefits but the prebiotics are indigestible ingredients that enhance the activity of one or more probiotics in the colon. The therapeutic potential of these two biological active ingredients is the outcome of emerging field of biotechnology. A number of studies indicating therapeutic potential of probiotics regarding gastrointestinal health, cancer, constipation, immunomodulation, Helicobacter pylori, liver disease and urogenital infection have been documented. Similarly, prebiotics also improved helpful for many communicable and non-communicable diseases. It can be seen that advancement in the biotechnology field offer great choice to deliver a marvelous health advantages. Although the market for probiotic and prebiotic food and supplements has been increased in this new era but still need to develop food and supplements containing these two active ingredients with the cooperation of legal bodies of the country.

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“…Multiple organisms (Lactobacillus acidophilus LA05® and Streptococcus lactis BB-12®) have been combined with good therapeutic effect for treatment of inflammatory bowel disease [21]. At times, single-strain probiotics have been reported as more preserving of renal function [44].…”

Section: Probioticsmentioning

confidence: 99%

“…Excessive blood urea nitrogen concentrations have been shown to be associated with an increased risk for diabetes mellitus [74] as well as engendering multiple other toxicities [75]. Urea concentrations can be decreased by probiotic administration [44]. Amine production has been noted to be reduced by the use of probiotics [76] as well as levels of indoxyl sulfate and p-cresyl sulfate [35,36].…”

Section: Kidney Failurementioning

confidence: 99%

“…These analyses confirm beneficial effects on uremic toxins [35,36] inflammation, and gastrointestinal symptoms [35] but not preservation of kidney function (Table 1). However, variations in probiotic supplement used, study design, underlying kidney disease, and absence of baseline kidney function determinations have limited the value of meta-analyses [35,36,44]. In this review, we focus on using probiotics to restore a metabolically balanced gastrointestinal tract in CKD patients and, most importantly, to decelerate CKD progression.…”

Section: Introductionmentioning

confidence: 99%

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Reality of "Enteric Dialysis ®" with Probiotics and Prebiotics to Delay the Need of Conventional Dialysis

Ranganathan¹

2018

J Nephrol Ther

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Probiotics and prebiotics are generally used for gut, immune and digestive health. However, we have been looking outside the box for the use of probiotics and prebiotics toward help in maintaining healthy kidney function. The gut microbiome is unfavorably altered (i.e., dysbiosis) in individuals with renal impairment, promoting progressive renal failure, persistent systemic inflammation, and small bowel bacterial overgrowth (SBBO). A probiotic that delays the progression of kidney failure would have enormous impact as millions of individuals worldwide suffer from chronic kidney disease and, not all individuals; especially in low income countries have access to chronic dialysis care. Probiotics have demonstrated their ability to remove uremic toxins, and early studies indicate the slowing of renal disease progression. The role of probiotics in managing renal failure is not yet clearly defined, but the data thus far, suggest that probiotics will prove to play a significant role in chronic kidney disease management.

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The effects of prebiotic, probiotic, and synbiotic supplementation on blood parameters of renal function: A systematic review and meta-analysis of clinical trials

Cited by 35 publications

References 39 publications

Rebuilding the Gut Microbiota Ecosystem

Rebuilding the Gut Microbiota Ecosystem

Therapeutic Potential of Probiotics and Prebiotics

Reality of "Enteric Dialysis ®" with Probiotics and Prebiotics to Delay the Need of Conventional Dialysis

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