The effects ofTarantula cubensisvenom on open wound healing in rats

Abstract

Our results suggest that alcohol extract of Tarantula cubensis accelerates epithelialisation and, thus, has beneficial effects on open wound healing in rats.

Samsum ant venom modulates the immune response and redox status at the acute toxic dose in vivo

“…For this, the splenic tissues were homogenized (Automated homogenizer, IKA, T25D, Germany) in 10 mM KCl in 1.15% PBS and ethylenediaminetetraacetic acid (EDTA; pH 7.4) and centrifuged at 5000 × g for 10 minutes. The resulting supernatant was used to estimate the level of MDA and GSH by the established methods [21,22,23].…”

Gastroprotective effect of tarantula cubensis extract in the indomethacin-induced peptic ulcer model in rats

“…Indomethacin was purchased from Sigma Aldrich (St. Louis, MO, USA) and Theranekron® alcoholic extract (1:100) of Tarantula cubensis in alcoholic solution 1 mg/ml, was purchased from Richter-Pharma AG, Wels, Austria. Indomethacin was dissolved in the saline and the TCE dose was selected based on the previous studies [9].…”

“…Tarantula cubensis extract (TCE) is commonly used in the veterinary field [7], [8]. Although, major mechanism behind the therapeutic effects of TCE is not clearly identified, it is commonly believed that stimulation of cellular defense mechanisms and boosting of the anti-inflammatory mechanism occurs in favor of the healing of the inflammatory lesions, such several ulcers and abscess [9], [10]. Therefore, it is rational to think that the suggested anti-inflammatory and wound-healing properties of TCE might be have beneficial effects in the gastric ulcer treatment.…”

Tavşanlarda Tarantula Cubensis Ekstraktı ve Düşük Enerjili Lazer Uygulanan Deneysel Kemik Defektlerinin İyilesmesinde Osteonektin ve Ostekalsinin Etkilerinin Araştırılması

“…Homeopatik ilaçlardan olan theranekron, Tarantula cubensis örümceğinden elde edilen Tarantula cubensis özütünün alkolde çözdürülmüş formudur (23). Sığır deri papillomatozis, köpek meme adenokarsinomları, sıçanlarda travmatik tendon yaralanmaları ve birçok inflamatuar lezyonda ve yara iyileşmesi gibi yumuşak doku hasarlarının tedavisinde faydalı etkilerini olduğu bildirilmiştir (23,39,40). Kemik kırık ya da defekt iyileşmesinde rolü ile ilişkili birkaç çalışma mevcut olup (21,23,24), kemik defekt bölgesinden osteokalsin ve osteonektin ekspresyonlarında etkili olup olmadığına dair çalışmalar bulunmamaktadır.…”