The effects of a new soluble dietary fiber on weight gain and selected blood parameters in rats

Artiss, Joseph D.; Brogan, Kathryn; Brucal, Michelle; Moghaddam, Marjan; Jen, K.‐L. Catherine

doi:10.1016/j.metabol.2005.08.012

Cited by 98 publications

(74 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…2) Production of SCFA from fiber fermentation especially Butyrate has been identified as a modulator of histone tail acetylation and consequently, increases the accessibility of many genes to transcriptional factors 3) Modulation of mucin production, 4) FOS and some other prebiotics have shown increased lymphocyte and/or leucocyte numbers in gut-associated lymphoid tissues (GALT) and peripheral blood, 5) Enhanced IgA secretion by the GALT is said to stimulate the phagocytic function of intraperitoneal macrophages (Schley and Field 2002). Experimental data in animals demonstrated that inulin supplementation increased SCFA in the caecum (Artiss et al 2006). Synbiotics seems to be quite attractive proposition for enhancing the immune function.…”

Section: Immunomodulationmentioning

confidence: 99%

Probiotics, prebiotics and synbiotics- a review

Pandey¹,

Naik²,

Vakil³

2015

J Food Sci Technol

910

572

View full text Add to dashboard Cite

The health benefits imparted by probiotics and prebiotics as well as synbiotics have been the subject of extensive research in the past few decades. These food supplements termed as functional foods have been demonstrated to alter, modify and reinstate the pre-existing intestinal flora. They also facilitate smooth functions of the intestinal environment. Most commonly used probiotic strains are: Bifidobacterium, Lactobacilli, S. boulardii, B. coagulans. Prebiotics like FOS, GOS, XOS, Inulin; fructans are the most commonly used fibers which when used together with probiotics are termed synbiotics and are able to improve the viability of the probiotics. Present review focuses on composition and roles of Probiotics, Prebiotics and Synbiotics in human health. Furthermore, additional health benefits like immune-modulation, cancer prevention, inflammatory bowel disease etc. are also discussed.

show abstract

Section: Immunomodulationmentioning

confidence: 99%

Probiotics, prebiotics and synbiotics- a review

Pandey¹,

Naik²,

Vakil³

2015

J Food Sci Technol

910

572

View full text Add to dashboard Cite

show abstract

“…FBCx  , the trade name used by ArtJen Complexus Holdings Corp. for α-cyclodextrin, has been shown to bind with free fatty acids in aqueous solution [13]. Animal research has shown that FBCx reduced weight gain in rats [14]. In addition, FBCx reduced blood triglyceride and leptin levels, as well as improved the calculated insulin sensitivity [14].…”

Section: Introductionmentioning

confidence: 99%

The benefits of early intervention in obese diabetic patients with FBCx^™ — a new dietary fibre

Grunberger

Jen²,

Artiss³

2006

Diabetes Metabolism Res

Self Cite

View full text Add to dashboard Cite

show abstract

“…Os efeitos benéfi cos das fi bras solúveis na atenuação da dislipidemia têm sido relatados em diversos estudos, tanto em animais (Junqueira-Guertzenstein & Srur, 2002;Behall et al, 2004;Artiss et al, 2006) quanto em humanos (Chandalia et al, 2000;Jenkins et al, 2005;Ramos et al, 2007). Todavia, em outros estudos esses efeitos não foram totalmente comprovados, portanto faz-se necessário um aprofundamento maior sobre seus benefícios.…”

Section: Discussionunclassified

Efeito da farinha da casca do maracujá-amarelo (Passiflora edulis f. flavicarpa Deg.) nos níveis glicêmicos e lipídicos de pacientes diabéticos tipo 2

Janebro¹,

Queiroz²,

Ramos³

et al. 2008

Rev. bras. farmacogn.

View full text Add to dashboard Cite

RESUMO: A suplementação da dieta com fi bras solúveis pode ser considerada uma importante medida terapêutica no tratamento de pacientes diabéticos e obesos. Para avaliar o efeito da farinha da casca de maracujá amarelo rica em pectina, foi realizado um ensaio clínico fase II com 43 pacientes portadores de Diabetes Mellitus tipo 2. Estes receberam diariamente 30 g do produto testado durante 60 dias. Observou-se diferença estatística signifi cante na glicemia de jejum (p = 0,000) acompanhada pela redução nos valores médios da hemoglobina glicada (p = 0,032). Em relação ao perfi l lipídico, não foi verifi cado redução dos níveis de colesterol total e colesterol LDL nos pacientes ao longo deste estudo; entretanto, houve redução nos níveis de Triglicerídeos e aumento do colesterol HDL nos mesmos. Os níveis glicêmicos apresentados pelos pacientes antes e após o uso da farinha da casca do maracujá são compatíveis com uma ação positiva no controle da glicemia como adjuvante das terapias convencionais. Unitermos:Passifl ora edulis, Passifl oracea, pectina, diabetes, atividade hipoglicemiante, produtos naturais.ABSTRACT: "Effect of the fl our of the yellow passion fruit peel (Passifl ora edulis f. fl avicarpa Deg.) in the glycemic and lipid levels of type 2 diabetes patients". The supplementation of diet with soluble dietary fi ber can be considered an important therapy measure in the treatment of diabetic and obese patients. In order to evaluate the effect of the fl our of the yellow passion fruit peel which is rich in pectin, a phase II clinical trial with 43 patients with type 2 Diabetes Mellitus was performed. They received daily 30 g of the tested product for 60 days. Statistically signifi cant difference was observed in fasting plasma glucose (p = 0.000) accompanied by a reduction in the average values of glycated hemoglobin (p = 0.032). In relation to the lipid profi le, there were no reduced levels of total cholesterol and LDL-cholesterol in patients during this study; however, there were reduction in the levels of Triglycerides and increase in HDL cholesterol in them. The glycemic levels presented by the patients before and after the use of the passion fruit peel fl our are compatible to a positive action to control blood glucose as an adjunct of conventional therapies. Keywords:Passifl ora edulis, Passifl oracea, pectin, diabetes, hypoglycemic activity, natural products. INTRODUÇÃOO Diabetes Mellitus (DM) constitui um grave problema de saúde pública por sua alta prevalência na população, suas complicações crônicas, mortalidade, altos custos fi nanceiros e sociais envolvidos no tratamento e deterioração signifi cativa da qualidade de vida.Em países, como o Brasil, está previsto aumento na prevalência de DM de 170% no período de 1995de a 2025de (King et al., 1998Narayan et al., 2000;Figueiredo & Modesto-Filho, 2008). Mesmo em países desenvolvidos, apesar dos avanços científi cos e o acesso fácil a cuidados contínuos de saúde, a prevalência do diabetes está aumentando e intervenções com a fi nalidade de prev...

show abstract

The effects of a new soluble dietary fiber on weight gain and selected blood parameters in rats

Cited by 98 publications

References 43 publications

Probiotics, prebiotics and synbiotics- a review

Probiotics, prebiotics and synbiotics- a review

The benefits of early intervention in obese diabetic patients with FBCx^™ — a new dietary fibre

Efeito da farinha da casca do maracujá-amarelo (Passiflora edulis f. flavicarpa Deg.) nos níveis glicêmicos e lipídicos de pacientes diabéticos tipo 2

Contact Info

Product

Resources

About

The effects of a new soluble dietary fiber on weight gain and selected blood parameters in rats

Cited by 98 publications

References 43 publications

Probiotics, prebiotics and synbiotics- a review

Probiotics, prebiotics and synbiotics- a review

The benefits of early intervention in obese diabetic patients with FBCx™ — a new dietary fibre

Efeito da farinha da casca do maracujá-amarelo (Passiflora edulis f. flavicarpa Deg.) nos níveis glicêmicos e lipídicos de pacientes diabéticos tipo 2

Contact Info

Product

Resources

About

The benefits of early intervention in obese diabetic patients with FBCx^™ — a new dietary fibre