The Effect of Various Amounts of Caffeine on the Gaseous Exchange and the Respiratory Quotient in Man

Haldi, John; Bachmann, George; Ensor, Charles R.; Wynn, Winfrey

doi:10.1093/jn/21.3.307

Cited by 24 publications

(9 citation statements)

References 16 publications

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“…The increase, 298+150%, is highly significant @<0.001).Caffeine has many effects in different organs, but the mechanisms of action are still incompletely understood (1). We have recently found (2) that this drug stimulates overall platelet metabolism, as measured by microcalorimetry, in agreement with previous studies (3,4) showing that the basal metabolic rate in man increases during caffeine administration. Derangement of platelet metabolism can be expected to lead to abnormalities of cell functions.…”

supporting

confidence: 92%

Caffeine Stimulates in vivo Platelet Reactivity

Ammaturo

Perricone²,

Canazio³

et al. 1988

Journal of Internal Medicine

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The effect of coffee drinking on platelet reactivity was studied in 12 healthy subjects. Plasma beta‐thromboglobulin concentration was determined before and one hour after administration of 100 mg of caffeine, corresponding to one cup of coffee. Mean values were 47.0±19.3 and 179.3±85.5 ng/ml before and after caffeine administration respectively. The increase, 298±150%, is highly significant (p<0.001).

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supporting

confidence: 92%

Caffeine Stimulates in vivo Platelet Reactivity

Ammaturo

Perricone²,

Canazio³

et al. 1988

Journal of Internal Medicine

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“…Although their respiratory effects on humans have been known for some time [1][2][3], it was not until 1973 that Kuzemko and Paala [4] first re ported the use of rectal aminophylline to treat premature infants with apnea and re spiratory distress syndrome. Subsequently other investigators have substantiated the usefulness of caffeine and theophylline in the treatment of apnea of prematurity [5][6][7][8][9] and as an aid to extubation [10][11][12], The pharmacokinetics of both caffeine and theophylline have been widely studied in animals and humans [13][14][15][16][17][18][19] and a num ber of plasma metabolites have been identi…”

Section: Introductionmentioning

confidence: 99%

Caffeine Pharmacokinetics in Preterm Infants Older than 2 Weeks

Durán

et al. 1989

Dev Pharmacol Ther

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We studied 17 preterm infants receiving caffeine, and measured their plasma levels of caffeine and the theophylline metabolite by high-pressure liquid chromatography. The half-life was calculated by computer analysis using the least-square method. The mean gestational age of our patients was 29.7 ± 1.9 weeks (mean ± SD) and they were studied at 20.7 ± 6.6 days (mean ± SD) postnatal age. The caffeine half-life was 52.03 ± 23.87 h (means ± SD) and the theophylline half-life was 77.04 ± 65.01 h (mean ± SD).

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“…The effect on speed and power in long-term exercises Studies on the effect of caffeine on performance or speed in endurance exercises are rarely conducted. Some studies determined that caffeine often increases performance in activities such as stepping up and repetitive jumping as well as sprint test and cycling [51,52,53,54]. These studies were often applied to small groups and in protocols that are not accepted today.…”

Section: Caffeine and Exercise Relationshipmentioning

confidence: 99%

The examination of the effect of caffeine supplementation in professional soccer players

Karabağ¹,

Taş²

2019

PES

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Purpose: In this study, the effects of caffeine supplementation in professional soccer players on the Hoff and sprint tests were examined. Material: 11 professional soccer players participated in this study in line with this purpose (Xage=20.636). The Hoff and sprint tests were applied 3 times at 1 week intervals. In each of these practices, caffeine added water was performed on the participants in the first week, and placebo was performed in the second week. In the third week, the participants were tested without any additional supplement. This practice lasted 3 weeks. Caffeine supplementation was given to each participant with the amount of 6 mg / kg in 200 ml water 1 hour before the tests, and placebo supplementation in 200 ml water was given 1 hour before the tests. The soccer players did the hoff test and sprint test respectively after 20 minutes of warming period. Results: Following Wilcoxon signed-ranks analysis, it was found that caffeine supplementation and placebo applications significantly increased the hoff test averages (p <0.05), while sprint test averages were reduced significantly in statistical terms (p <0.05). Conclusions: As a conclusion, we can state that caffeine application significantly increased the hoff test averages in comparison to placebo (p <0.05), and that it caused sprint test averages to decrease significantly in statistical terms (p <0.05).

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The Effect of Various Amounts of Caffeine on the Gaseous Exchange and the Respiratory Quotient in Man

Cited by 24 publications

References 16 publications

Caffeine Stimulates in vivo Platelet Reactivity

Caffeine Stimulates in vivo Platelet Reactivity

Caffeine Pharmacokinetics in Preterm Infants Older than 2 Weeks

The examination of the effect of caffeine supplementation in professional soccer players

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