The effect of sublethal levels of copper on oxygen consumption and ammonia excretion in the common carp, Cyprinus carpio

Boeck, Gudrun De; Smet, Hyo Jung De; Blust, Ronny

doi:10.1016/0166-445x(94)00086-6

Cited by 95 publications

(58 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These observations are consistent with suggestions that high levels of circulating glucose in response to stressor are sustained by increased plasma cortisol after an initial catecholamine-induced increase [16,17]. Increased lactate levels after heavy metal exposure are considered to result from anaerobic metabolism caused by gill impairment [28]. In the present study, plasma lactate was significantly elevated after 72 h exposure.…”

Section: Hematological Responses To Cadmium Exposuresupporting

confidence: 81%

Exposure of silver carp (Hypophthalmichthys molitrix) to environmentally relevant levels of cadmium: hematology, muscle physiology, and implications for stock enhancement in the Xiangjiang River (Hunan, China)

Zhang

Zhuo

et al. 2013

Sci. China Life Sci.

View full text Add to dashboard Cite

Cadmium is a non-essential metal with a wide distribution that has severe toxic effects on aquatic animals. Changes in hematology and muscle physiology were examined in silver carp (Hypophthalmichthys molitrix) exposed to environmentally relevant levels of cadmium (0.01 mg L 1 ) for 96 h. Cadmium exposure induced significant increases in the red blood cell count, and in the plasma concentrations of cortisol, glucose, and lactate. This suggests that the dose of cadmium was sufficient to cause stress, possibly associated with impaired gas exchange at the gills. There were no changes in hemoglobin concentration or plasma protein concentration. Significant decreases in muscle energy fuels (ATP and glycogen), and increases in muscle lactate persisted until the end of the exposure period, respectively. The changes in muscle lactate and protein in silver carp differed from those observed in response to exposure of fish to cadmium and heavy metals in other studies. The study highlights the importance of selecting unpolluted release sites with suitable water conditions for the survival of newly released individuals for stock enhancement of the Xiangjiang River. silver carp, hematology, muscle physiology, cadmium exposure, stock enhancement Citation:Zhang T, Zhang Y, Li D L, et al. Exposure of silver carp (Hypophthalmichthys molitrix) to environmentally relevant levels of cadmium: hematology, muscle physiology, and implications for stock enhancement in the Xiangjiang River

show abstract

Section: Hematological Responses To Cadmium Exposuresupporting

confidence: 81%

Exposure of silver carp (Hypophthalmichthys molitrix) to environmentally relevant levels of cadmium: hematology, muscle physiology, and implications for stock enhancement in the Xiangjiang River (Hunan, China)

Zhang

Zhuo

et al. 2013

Sci. China Life Sci.

View full text Add to dashboard Cite

show abstract

“…Increased LDH activity is known to be a sign of anaerobic metabolism and is often a consequence of slight tissue damage -in our study, the consequence of liver damage. On the other hand, the liver still retains the ability to scavenge lactate from plasma (Gill et al 1992;De Boeck et al 1995). …”

Section: Discussionmentioning

confidence: 99%

“…Both increased ammonia production and the inhibition of its excretion could explain such observations. Cortisol, produced in fish under stress, stimulates protein metabolism, resulting in increased ammonia plasma levels (De Boeck et al 1995;De Boeck et al 2001). The mechanism behind the decreased excretion of ammonia via the gills, caused by copper, could be connected with the inhibition of the branchial enzyme carbonic anhydrase and the reason why ammonia in the form of NH 4 + remains trapped in gill cells (Wilson et al 1994).…”

Section: Discussionmentioning

confidence: 99%

Biochemical, haematological and oxidative stress responses of common carp (Cyprinus carpio L.) after sub-chronic exposure to copper

Ševčíková¹,

Modrá²,

Blahová³

et al. 2016

Vet. Med.

View full text Add to dashboard Cite

ABSTRACT:The aim of the present study was to investigate the impact of copper-based pesticides (at concentrations of copper of 20, 30, 40 and 70 µg/l) on one-year-old common carp (Cyprinus carpio L.) during 28 days of exposure. Abnormal behaviour was observed in fish exposed to 70 µg/l from Day 14. Histological alterations were noticed only in liver in the groups exposed to 40 and 70 µg/l. Significant changes (P ˂ 0.05) in almost all haematological indices were found, especially in the group exposed to the highest concentration of copper (70 µg/l). Biochemical analysis revealed various significant (P ˂ 0.05) differences among the tested groups. Significant differences in copper tissue concentration (P ˂ 0.05) among groups were found in liver, gills and kidney. Among antioxidative enzymes, significant changes were revealed mainly in catalase and glutathione-S-transferase activity (P ˂ 0.05). In gills, metallothionein content increased significantly (P ˂ 0.05) in the group exposed to the highest copper concentration (70 µg/l) compared with the other tested groups, including the control. A significant (P ˂ 0.05) change in total glutathione content was recorded in liver and gills, although the reduced/oxidised ratio was not affected. Oxidative damage to lipids increased significantly (P ˂ 0.05) with increasing copper concentration in liver and kidney. The results demonstrate the deleterious influence of copper on common carp even at low, environmentally relevant concentrations.

show abstract

“…Moreover, in the storage pond there was a very low oxygen saturation (16%). Such stress factors result in disbalance in the ammonia production and excretion (Evans 1993;Konovets et al 1993;De-Boeck et al 1995;Svobodová et al 1997a), leading to fish autointoxication by ammonia. Unfortunately, this hypothesis could not be confirmed at the end of the transport as the fish were dead.…”

Section: Discussionmentioning

confidence: 99%

The Effect of Handling and Transport of the Concentration of Glucose and Cortisol in Blood Plasma of Common Carp

Svobodová¹,

Kaláb²,

Dušek³

et al. 1999

Acta Vet. Brno

View full text Add to dashboard Cite

Svobodová Z., P. Kaláb, L. Du‰ek, B. Vykusová, J. Koláfiová, D. Janou‰ková: Glucose and Cortisol in Blood Plasma of Common Carp. Acta Vet. Brno 1999, 68: 265-274. The Effect of Handling and Transport on the Concentration ofThe aim of this contribution was to assess the degree of stress in common carp (Cyprinus carpio, L.) exposed to handling and transport. Cortisol and glucose concentrations in blood plasma were used as stress indicators. In some cases, concentration of ammonia in blood plasma and relative weight of spleen (SSI) were used as well. Within handling, an effect of time pause (0; 2 and 5 min) between catching the fish from water and blood sampling for stress indicators was checked. Another goal was to assess the effect of Menocain anaesthetics on the stress indicators. An open system of a 10-hour transport in a special long-distance live fish transport truck (Transport I a II), and a 2-hour transport in classic transporting tanks (Transport III) were compared. Temperature and oxygen concentration in water was measured during transport. After handling the fish prior to blood sampling (2 and 5 min pause), the cortisol concentration dropped significantly (p < 0.001) and the glucose concentration significantly (p < 0.001) increased compared to values in fish sampled immediately after catching. No effect of anaesthetics on cortisol concentration was proved. On the contrary, the glucose concentration fell (p = 0.012) in the anaesthetized fish. After a 10-hour transport in a special truck (Transport I), a significant (p < 0.001) decrease of the cortisol concentration was found, as well as a significant (p < 0.001) increase in the glucose concentration in blood plasma. In the course of 10-hour transport in a special truck (Transport II), the majority of carp was found dead. Suffocation and ammonia autointoxication due to loading the fish with full digestive tract were the most probable causes of the fish mortality. After a 2-hour transport in transporting tanks (Transport III) both the cortisol concentration and relative weight of spleen (SSI) dropped non-significantly while glucose concentration in blood plasma significantly (p < 0.001) increased. Results showed that both handling and transport are important stressors in the common carp. Preventive measures were proposed aimed at alleviating the negative effects of these stressors.

show abstract

The effect of sublethal levels of copper on oxygen consumption and ammonia excretion in the common carp, Cyprinus carpio

Cited by 95 publications

References 19 publications

Exposure of silver carp (Hypophthalmichthys molitrix) to environmentally relevant levels of cadmium: hematology, muscle physiology, and implications for stock enhancement in the Xiangjiang River (Hunan, China)

Exposure of silver carp (Hypophthalmichthys molitrix) to environmentally relevant levels of cadmium: hematology, muscle physiology, and implications for stock enhancement in the Xiangjiang River (Hunan, China)

Biochemical, haematological and oxidative stress responses of common carp (Cyprinus carpio L.) after sub-chronic exposure to copper

The Effect of Handling and Transport of the Concentration of Glucose and Cortisol in Blood Plasma of Common Carp

Contact Info

Product

Resources

About