The effect of SNP polymorphisms in growth hormone gene on weight and linear growth in crossbred Red Angus × Kalmyk heifers

Abstract

The aim of our research was to study the effect of single-nucleotide polymorphisms in growth hormone gene on variability of weight and linear growth in crossbred Red Angus × Kalmyk heifers (F2). The experimental animals were reared in "Agrofirma Aduchi" Ltd. in Tselinniy region, Republic of Kalmykia. Heifers were divided into groups after genotyping in accordance with the allelic variant of the growth hormone gene: I group completed with GH LV heterozygous animals (n = 11 heads), II grouprepresentatives of the homozygous GH VV gene (n = 9 heads). The inter-group differences in live weight were insignificant (P> 0.05) between the carriers of various genotype variants in growth hormone gene in the weaning age (8 months). The advantage in live weight between experimental animals increased to 23.9 kg (P <0.05) at the final stage of the control rearing (18 months). In this period, heterozygous youngsters (GH LV) differed in a large format of the exterior compared to homozygous contemporaries (GH VV). The significant superiority was established absolutely for all studied measurements. The maximum effect of heredity factor on the variability of live weight was detected at the age of 18 months-24.81% (P <0.05). The calculation of the organized factor impact to the overall variability of linear growth in heifers of different allelic variants for the GH gene showed significance (P <0.05) at 18 months of age. Thus, the detection of single-nucleotide polymorphisms in GH gene can improve the accuracy of the selection in beef herds.

Single nucleotide polymorphisms of growth hormone gene in cattle and their association with growth traits: a systematic review

“…The results indicated that the included articles were from different countries such as Indonesia, Colombia, Mexico, Russia, United State, Thailand, Ukraine, and China. In addition, the findings revealed that the majority (27%) of the included articles were from Indonesia (Agung et al 2017;Fathoni et al 2019;Putra et al 2019;Maskur & Arman 2014) followed by (13%) Colombia (Arango et al 2014;Martinez et al 2016), Mexico (Garrett et al 2008;Thomas et al 2007), Russia (Kayumov et al 2019;Sedykh et al 2020) and United State (Beauchemin et al 2006;Ge et al 2003), while the least (7%) included articles were from Thailand (China et al 2007), Ukraine (Ruban et al unknown), and China (Zhang et al 2011).…”

“…All included articles investigated growth hormone gene and its association with growth traits in cattle. The Angus cattle breed being most investigated (Ge et al 2003;Kayumov et al 2019;Ruban et al unknown) accounting for 20% (n = 3) of the included articles.…”

“…(6.66%), 2006 (6.66%), 2007 (13.33%), 2008 (6.66%), 2011 (6.66%), 2014 (13.33%), 2016 (6.66%), 2017 (6.66%), 2019 (20%), 2020 (6.66%) and unknown (6.66%). The results showed that most included articles were published in year 2019 (Fathoni et al 2019;Putra et al 2019;Kayumov et al 2019).…”

The Impact of Steer Genotype on Protein and Mineral Metabolism

“…In this respect, the Simmental breed has recently attracted the attention of breeders. Animals of this breed have a high level of meat productivity and pass this trait to their offspring in crossbreeding (Vil'ver et al, 2017;Kosilov et al, 2017;Zadnepryanskii et al, 2012;Kayumov et al, 2019;Mironova et al, 2018).…”

“…The effect of crossbreeding on meat production can only be seen if a full, balanced feed is provided to the crossbreds. This can be monitored by determining the balance of nutrients and minerals in the body of fattened young animals (Kosilov et al, 2006;Nikonova et al, 2014;Kosilov et al, 1997;Bozymov et al, 2016;Speshilova et al, 2014;Nagdalian et al, 2020;Vil'ver et al, 2017;Kosilov et al, 2017;Zadnepryanskii et al, 2012;Kayumov et al, 2019;Mironova et al, 2018;Fatkullin et al, 2018;Sedykh et al, 2018;Tyulebaev et al, 2019).…”