The effect of serum vitamin D levels on ovarian reserve markers: a prospective cross-sectional study

Abstract

N/A.

Evaluation of vitamin D status and its correlation with gonadal function in children at mini‐puberty

“…9,10 Many human studies have also demonstrated an association between serum vitamin D concentrations and gonadal hormone production. [15][16][17][18] Therefore, the literature is conflicting and complete characterization of the association of vitamin D levels with the gonadal function remains to be elucidated. [15][16][17][18] Therefore, the literature is conflicting and complete characterization of the association of vitamin D levels with the gonadal function remains to be elucidated.…”

Independent association of serum vitamin D with anti‐Mullerian hormone levels in women with polycystic ovary syndrome

“…In contrary, a retrospective study by Pearce et al on 340 infertile women (58 had PCOS and 282 were ovulatory) failed to demonstrate any seasonal fluctuation of serum AMH with vitamin D status in either the PCOS or ovulatory subgroups. Another more recent prospective cross‐sectional study involving 283 infertile women with 26 of them having a diagnosis of PCOS also showed no correlation between 25(OH)D and AMH . The differences in inclusion criteria, sample size, geographical and genetic factors, study design as well as assays used for the measurement of vitamin D and AMH and their differential performance may have contributed to the discrepancies observed in the various studies.…”

“…In vitro, 25(OH)D levels in follicular fluid are negatively correlated with AMH and AMH receptor‐II mRNA levels in cumulus granulosa cells of small follicles, suggesting that AMH signalling and steriodogenesis can be altered by vitamin D level. A correlation between serum 25(OH)D and AMH level has been reported, but other clinical studies do not find such correlation . Recently, serum AMH level is found to be increased after vitamin D supplementation .…”

“…A correlation between serum 25(OH)D and AMH level has been reported, 17 but other clinical studies do not find such correlation. 18,19 Recently, serum AMH level is found to be increased after vitamin D supplementation. 20 If a clear relationship is confirmed between vitamin D and AMH, it can lead to a better understanding of the pathophysiology of PCOS and prompt novel potential treatments of anovulation secondary to PCOS.…”

Pathogenetic role of vitamin D deficiency in the development of menstrual dysfunction in pubertal girls: a literature review

“…However, there is still no consensus on the mechanisms and extent of the impact of vitamin D deficiency on steroidogenesis, follicular development and ovarian reserve [14]. Some researchers explained the connection between vitamin D levels in serum and menstrual function through mediated mechanisms.…”