The effect of gender and age on postoperative pain in laparoscopic cholecystectomy: a prospective observational study

Chae, Kyoung Lin; Park, Sang Yoong; Hong, Jeong In; Yim, Woo Jae; Lee, Seung Cheol; Chung, Chan Jong

doi:10.17085/apm.2019.14.3.364

Cited by 9 publications

(8 citation statements)

References 19 publications

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“…18 Some evidence suggests that women may experience more pain and require more medication than men to achieve similar analgesia in laparoscopy. 19 Our study, as in previous gynaecological studies, that only focuses on women, may detect an analgesic benefit that may not be seen if extrapolated to the general surgical population that includes both men and women.…”

Section: Discussionmentioning

confidence: 56%

The effect of intraperitoneal ropivacaine on post‐operative pain and recovery after diagnostic laparoscopy and hysteroscopy: A randomised double‐blind placebo‐controlled trial

Frawley

Jones

Pearce

et al. 2021

Aust NZ J Obst Gynaeco

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Background: Intraperitoneal local anaesthetic has shown benefit in operative laparoscopy; however, no randomised controlled trial has been reported with patients having diagnostic laparoscopy. Aims:To determine the effect of intraperitoneal ropivacaine on post-operative analgesic requirements, pain, nausea scores and recovery following gynaecological diagnostic laparoscopy and hysteroscopy. Materials and Methods:Randomised double-blind placebo-controlled trial. Well women aged 18-50 years, undergoing day case hysteroscopy and diagnostic laparoscopy for gynaecological indications were randomised to 20 mL of 150 mg intraperitoneal ropivacaine diluted in saline, or 20 mL normal saline instillation (placebo) at the end of the procedure. Women were followed up until eight hours post-discharge.Results: Slower than anticipated recruitment meant that the study was finished before the sample size of 100 patients was achieved. Fifty-nine patients were included for analysis. Thirty-one patients were randomised to ropivacaine and 28 patients to control. Sixty-one percent of patients in both arms required opioid medication in recovery. The total median equivalent morphine dose was significantly higher in the patients randomised to control (11.7 mg) vs ropivacaine (6.7 mg), P = 0.03. Time to discharge was 20 min faster in patients randomised to ropivacaine, but this finding did not reach significance. Overall pain and nausea scores in the first eight hours showed no significant differences. Conclusion:There was significantly reduced opioid use in recovery when using intraperitoneal ropivacaine compared to placebo, in this randomised placebo-controlled trial on women undergoing day case diagnostic laparoscopy and hysteroscopy. K E Y W O R D S laparoscopy, local anaesthetics, post-operative nausea and vomiting, post-operative pain, randomised controlled trial, patient recovery 119 N. Frawley et al.

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Section: Discussionmentioning

confidence: 56%

The effect of intraperitoneal ropivacaine on post‐operative pain and recovery after diagnostic laparoscopy and hysteroscopy: A randomised double‐blind placebo‐controlled trial

Frawley

Jones

Pearce

et al. 2021

Aust NZ J Obst Gynaeco

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“…Our finding showed that female patients required higher opioids in PACU. Female sex was previously found as a risk factor for increased postoperative pain on PACU admittance [19] requiring a higher fentanyl dose [20]. Sex hormones and receptors play a role on complex pain sensitivity for both pro-nociceptive and anti-nociceptive effects [21].…”

Section: Discussionmentioning

confidence: 99%

ABO blood group is not a predictive factor for the amount of early opioid consumption in postanesthesia care unit: a prospective cohort study in 3,316 patients

et al. 2022

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Background Immediate postoperative pain in the postanesthesia care unit (PACU) is common. Titration of opioid is the most popular strategy for controlling early postoperative pain. ABO blood group has been found to be associated with pain perception. We aimed to find the factors including ABO blood group for predicting the amount of opioid requirement in PACU. Methods This prospective cohort study was performed in 3316 patients who underwent various kinds of anesthetic techniques and received immediate postoperative care in PACU. Preoperative, intraoperative and PACU data were collected. A directed acyclic graph (DAG) representing the hypothesized causal pathways of preoperative, intraoperative and PACU data were compiled prior to conducting multinomial logistic regression analysis. Statistical significance in all models was defined as a P-value < 0.05. Results Female sex, body mass index, preoperative use of gabapentin, preoperative anxiety score, anesthetic techniques, type of operation, amount of consumed intraoperative opioids, intraoperative use of paracetamol, parecoxib and ondansetron, duration of anesthesia and surgery, amount of blood loss, pain upon PACU arrival, use of paracetamol and parecoxib in PACU were found to be factors influencing amount of opioid consumption in PACU. ABO blood group was not associated with early postoperative opioid requirement. Conclusions A significant number of factors are related to amount of opioid requirement in PACU. Some factors can be adjusted to provide better pain relief in early postoperative period. However, ABO blood group is not identified to be a predictive factor for early postoperative opioid consumption in PACU.

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“…In their study, the average patient's age was 42.97 ± 13.05 years old. Research by Chae et al, (2019) found significant differences between the sex of patients and postoperative pain relief also analgesic need. Young female patients needed higher doses of analgesics than elderly patients.…”

Section: Discussionmentioning

confidence: 99%

Adherence Level Of Medical Personnel In Implementing 2019 Postoperative Pain Management Guidelines

Nasrulloh¹,

Hamzah

Utariani

et al. 2021

JHS

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Introduction: Inadequate pain management may increase the risk of complications and postoperative chronic pain. Postoperative Pain Management Guidelines of The Anesthesiology and Reanimation Department, Faculty of Medicine Universitas Airlangga/ Dr. Soetomo Hospital Surabaya were arranged in 2019. Purposes: This study aim is to analyze the medical personnel’s adherence in implementing postoperative pain management guidelines. Methods: This is descriptive observational study with retrospective design. Total sampling was carried out on the medical records of patients who underwent elective surgery and received postoperative acute pain management during March-May 2020. Results: A total of 349 patients, most of the pain intensity was moderate (62.8%). The medical personnel adherence with postoperative pain management guidelines was 88.0%. The overall use of multimodal analgesia was 61.0%. Adherence to guidelines on pain category was mostly good adherence: 99.1% in mild pain, 82.6% in moderate pain, and 81.2% in severe pain. The use of multimodal analgesia was found in 12.3% mild pain; 83.6% moderate pain, and 100% severe pain patients. Conclusion: Most of the medical personnel have adhered to the postoperative pain management guideline, and widely-used multimodal analgesia. Systematic evaluation of guidelines implementation, patient satisfaction, and outcomes are needed.

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The effect of gender and age on postoperative pain in laparoscopic cholecystectomy: a prospective observational study

Cited by 9 publications

References 19 publications

The effect of intraperitoneal ropivacaine on post‐operative pain and recovery after diagnostic laparoscopy and hysteroscopy: A randomised double‐blind placebo‐controlled trial

The effect of intraperitoneal ropivacaine on post‐operative pain and recovery after diagnostic laparoscopy and hysteroscopy: A randomised double‐blind placebo‐controlled trial

ABO blood group is not a predictive factor for the amount of early opioid consumption in postanesthesia care unit: a prospective cohort study in 3,316 patients

Adherence Level Of Medical Personnel In Implementing 2019 Postoperative Pain Management Guidelines

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