The Effect of Drinking, Smoking and Physical Constitution on High Density Lipoprotein Cholesterol, Apolipoprotein AI and AII Levels.

Maeda, Kiyoshi; Hashimoto, Shuji; Okamoto, Kazushi; Saitō, Yukio; Ohtsuka, Tohru; Ohtsuka, S; Takahashi, Akira; Okamoto, Nobuo; Ohno, Kazuko; Hattori, Yasuko; Yagyu, Kiyoko; Toyoshima, Hideaki; Kato, Takashi

doi:10.1265/jjh.46.699

Cited by 5 publications

(10 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…One reason may have been the subjects' different drinking levels. Maeda et al (13) found a positive association between Apo AII and BMI only in females, but their female subjects included many nondrinkers (305/443, 68.8%).…”

Section: Discussionmentioning

confidence: 96%

“…In past studies (13,14), correlation between Apo AII and obesity was inconsistent. One reason may have been the subjects' different drinking levels.…”

Section: Discussionmentioning

confidence: 97%

“…Maeda et al (13), using simple correlation coefficients between Apo AII and BMI, reported a positive association between Apo AII and obesity only in females. However, they did not find this association in multiple regression analysis involving alcohol, smoking, BMI, and age as independent variables.…”

Section: Discussionmentioning

confidence: 99%

“…Several studies (12)(13)(14) reported that BMI negatively correlated with Apo AI. In the present study, multiple regression analysis showed that Apo AI negatively correlated with BMI, confirming the results of these previous studies (12)(13)(14). The relationship between Apo AI and BMI did not change in regards to the drinking levels of the subjects.…”

Section: Discussionmentioning

confidence: 99%

“…The relationship between obesity and Apo AII is not clear. Maeda et al (13) found a positive correlation between BMI and Apo AII only in females, whereas Meilahn et al (14) found none.…”

mentioning

confidence: 96%

See 4 more Smart Citations

Drinking Habits Influence the Relationship between Apolipoprotein AII and Body Mass Index.

Hosokai

Tamura

Koyama

et al. 1993

Journal of Nutritional Science and Vitaminology, J Nutr Sci Vit

View full text Add to dashboard Cite

SummaryThe relationships of cigarette smoking, exercise, and body mass index (BMI) to the serum levels of high-density lipoprotein (HDL) cholesterol, apolipoprotein AI (Apo AI), apolipoprotein All (Apo All), and % of HDL cholesterol to total cholesterol (%HDL-C) were assessed in 495 employees of a telephone company in Japan. They were subdivided into four groups by frequency of alcohol intake: nondrinkers (n=28), those who drank once per week (n=78), those who drank 2 to 5 times per week (n=245), and those who drank 6 to 7 times per week (n=144). Although univariate analysis before grouping showed a positive correla tion between Apo All and BMI, multiple analysis examined in each group showed the positive relationship only in the nondrinking group. The relationship between BMI and Apo AII would thus appear to depend on drinking habits.

show abstract

Section: Discussionmentioning

confidence: 96%

“…In past studies (13,14), correlation between Apo AII and obesity was inconsistent. One reason may have been the subjects' different drinking levels.…”

Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…The relationship between obesity and Apo AII is not clear. Maeda et al (13) found a positive correlation between BMI and Apo AII only in females, whereas Meilahn et al (14) found none.…”

mentioning

confidence: 96%

See 3 more Smart Citations

Drinking Habits Influence the Relationship between Apolipoprotein AII and Body Mass Index.

Hosokai

Tamura

Koyama

et al. 1993

Journal of Nutritional Science and Vitaminology, J Nutr Sci Vit

View full text Add to dashboard Cite

show abstract

Smoking and apolipoprotein levels: A meta-analysis of published data

et al. 2022

View full text Add to dashboard Cite

Smoking and plasma lipoproteins in man: effects on low density lipoprotein cholesterol levels and high density lipoprotein subfraction distribution

Freeman

Griffin

Murray

et al. 1993

Eur J Clin Investigation

118

View full text Add to dashboard Cite

In a survey of a healthy population (n = 197), LDL cholesterol, plasma triglycerides and VLDL triglycerides were found to be substantially increased and plasma HDL cholesterol decreased in smokers. The lipid-associated atherogenic risk in smokers as assessed by the LDL/HDL ratio was significantly higher [2.89 (SD 1.18, n = 63)] than in non-smokers [2.38 (SD 0.98, n = 86) P < 0.01]. The lower HDL level found in smokers was explained by a lower HDL-2 subfraction as determined by analytical ultracentrifugation. HDL 2b, 2a and 3a, measured by gradient gel electrophoresis, were all lower in the smokers but this was only significant for HDL 2a. Smoking had no effect on Lp(a) levels. HDL cholesterol and HDL-2 were strongly negatively correlated whereas LDL cholesterol and LDL/HDL ratio were strongly positively correlated with the plasma triglyceride concentration. There was a small but significant reduction in plasma CETP activity [non-smokers 49% t/microliter (SD 17, n = 90), smokers 43% t/microliter (SD 17, n = 66) P < 0.05] but CETP activity was not correlated with any measure of HDL in this population. Smoking was found to be an important independent contributor to the variation in plasma triglyceride, HDL, HDL-2 and LDL/HDL ratio. After correcting for sex, age, BMI, alcohol consumption, oral contraceptive use and plasma triglycerides smoking was still found to be significantly associated with HDL and the LDL/HDL ratio. Upon adjustment for covariant factors the mean differences between smokers and non-smokers for HDL cholesterol, HDL-2 and LDL/HDL were 0.15 mM, 16 mg dl-1 and 0.39 respectively. There appeared to be important sex differences in the influence of smoking on plasma lipoproteins. In women the main impact of smoking was on triglyceride levels and they in turn affected LDL and HDL. In contrast, in men, smoking had little impact on triglycerides and affected HDL more directly. We conclude that smoking cigarettes has an important effect on plasma lipoprotein metabolism through multiple mechanisms.

show abstract

The Effect of Drinking, Smoking and Physical Constitution on High Density Lipoprotein Cholesterol, Apolipoprotein AI and AII Levels.

Abstract: Through many epidemiological studies1,2), it has been proved that values of high density lipoprotein

Cited by 5 publications

References 22 publications

Drinking Habits Influence the Relationship between Apolipoprotein AII and Body Mass Index.

Drinking Habits Influence the Relationship between Apolipoprotein AII and Body Mass Index.

Smoking and apolipoprotein levels: A meta-analysis of published data

Smoking and plasma lipoproteins in man: effects on low density lipoprotein cholesterol levels and high density lipoprotein subfraction distribution

Contact Info

Product

Resources

About