The effect of cycloplegia on the ocular biometry and intraocular lens power based on age

Tuncer, İbrahim; Zengin, Mehmet Özgür; Yıldız, Serap

doi:10.1038/s41433-020-01131-3

Cited by 10 publications

(31 citation statements)

References 32 publications

(74 reference statements)

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“…Some studies have reported no signi cant change in keratometry readings following cycloplegia as in the present study [9,11,12,19]. However, the pupil dilation could effect the keratometric readings and corneal attening [13,21] or steeping [26] has been reported in the previous studies after cycloplegia. Although these differences in keratometric readings were statistically signi cant, they were not clinically signi cant in the previous studies.…”

Section: Resultssupporting

confidence: 55%

“…Tuncer at al. [13] found a signi cant attening by 0.054 D in the mean keraometric reading with AL-Scan in presbyopic eyes aged between 50 and 60 years of age. Cheng and Hsieh [21] proposed that during miosis, the contractive force of ciliary muscles (CMs) acts on the sclera spur where the ciliary body is attached, and the centripetal force of the peripheral cornea steepens the cornea.…”

Section: Resultsmentioning

confidence: 79%

“…1). However, some studies have reported a signi cant increase in AL readings of 50 mµ, 10 mµ, 13 mµ, respectively following cycloplegia induced by homatropine %2 [20], cyclopentolate hydrochloride 1% [13], and tropicamide %0.4 [21], respectively. Cheng and Hsieh [21] hypothesised that a posterior shift of the lens-ciliary body diaphragm occurs within 30 minutes after cycloplegia by tropicamide, and such a reaction may produce a compression force pushing toward the vitreous cavity which may cause temporary elongation of the AL.…”

Section: Resultsmentioning

confidence: 98%

“…Despite the results of our study, many studies have reported a signi cant increase in WTW after dilatation in presbyopics. These changes appear to be unveri able [10,13,25]. Huang et al [17] suggested that the image analysis system distinguishes the difference in the light and shade on the region between the iris and the sclera, and ts the best circle to the detected edge.…”

Section: Resultsmentioning

confidence: 99%

“…Several studies have shown that ACD increases after cycloplegia in pediatric and younger patients with non-presbyobic [10,13,17,21,27]. When cycloplegia eliminated accommodation, CMs are relaxed and pull the lens radially.…”

Section: Resultsmentioning

confidence: 99%

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The Effect of Pupil Dilation on Biometry Measurements Obtained by AL-Scan in the Cataractous Eyes

Üçer¹,

Bozkurt

Gökmen

2022

Preprint

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Purpose To evaluate the effect of cycloplegia on the biometric parameters and intraocular lens (IOL) power calculated by Sanders–Retzlaff–Kraff/theoretical (SRK/T) formula in the cataractous eyes. Methods This cross-sectional study included 68 senile cataractous eyes of 68 patients who were scheduled to undergo cataract surgery. Measurements of anterior chamber depth (ACD), axial length (AL), white to white (WtW) diameter, corneal power (K1, K2, Kmean), central corneal thickness (CCT), and pupil size (PS) were obtained with AL-Scan (Nidek Co., Ltd, Gamagori, Japan) before and after cycloplegia. The SRK/T formula was used to calculate IOL power with a target refraction of 0 D. Cycloplegia induced by cyclopentolate hydrochloride %1. Results The mean age of the patients was 70.60 ± 4.07 years (range 65 to 80). A significant increase was observed in ACD after cyloplegia (p < 0.001). There was not any statistically significant difference between pre-dilation and post-dilation AL, WtW, CCT, K1, K2, Kmean and IOL power readings (p > 0.05). A decrease above 0.5 D was observed after cycloplegia in two cases. Conclusion Cycloplegia induced by cyclopentolate hydrochloride %1 does not affect the measurement of the AL, WTW, CCT, keratometry and SRK/T calculated IOL power with the exception of ACD in cataractous eyes with AL-Scan.

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Section: Resultssupporting

confidence: 55%

Section: Resultsmentioning

confidence: 79%

Section: Resultsmentioning

confidence: 98%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

The Effect of Pupil Dilation on Biometry Measurements Obtained by AL-Scan in the Cataractous Eyes

Üçer¹,

Bozkurt

Gökmen

2022

Preprint

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Changes in ocular biological parameters after cycloplegia based on dioptre, age and sex

Tao

Cheng²,

Ouyang³

et al. 2022

Sci Rep

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The effects of cycloplegia on ocular biological parameters in children have been extensively studied, but few studies have compared these parameters between different refractive states, ages, and sexes. Therefore, the purpose of this study was to investigate the changes in ocular biometry before and after cycloplegia in different groups based on dioptre, age and sex. We examined a total of 2049 participants in this cross-sectional study. A comprehensive eye examination was conducted before cycloplegia. Cycloplegia was implemented with the application of atropine or tropicamide. Ocular biological parameters were evaluated after cycloplegia, including axial length (AL), mean keratometry (K), flat keratometry (K1), steep keratometry (K2), central corneal thickness (CCT), anterior chamber depth (ACD) and white-to-white (WTW) distance. All the participants were categorized based on dioptre, age and sex. Statistical analysis was performed with paired t tests and Wilcoxon signed-rank tests. Regarding dioptre, AL was found to be increased significantly in the Fs, Ast and FA (p < 0.05) postcycloplegia groups. We observed significant increases in K, K1, K2 and ACD in the Fs group (p < 0.05) after cycloplegia. Regarding age, we found significant increases in AL, CCT and ACD in group 1 (p < 0.05), but AL decreased significantly in groups 2 and 3 (p < 0.05) postcycloplegia. There were no significant changes found in K, K1 and K2 in the three groups after cycloplegia (p > 0.05). Regarding sex, AL and WTW were found to decrease significantly among males and increase significantly among females (p < 0.05) postcycloplegia, while K, K1 and K2 showed the opposite trends. This study showed that there were differences in some ocular biological parameters after cycloplegia across different groups; in particular, there were significant differences in AL, CCT and ACD. Attention should be devoted to the influence of cycloplegia in clinical work.

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Changes in ocular biometrics following cycloplegic refraction in strabismic and amblyopic children

Jo,

Kim,

Kim

et al. 2024

Medicine

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This study was aimed to analyze ocular biometric changes following cycloplegia in pediatric patients with strabismus and amblyopia. Cycloplegia is routinely used to measure refractive error accurately by paralyzing accommodation. However, effects on axial length (AL), anterior chamber depth (ACD), keratometry (Km), and white-to-white distance (WTW) are not well studied in this population. This retrospective study examined 797 patients (1566 eyes) undergoing cycloplegic refraction at a Samsung Kangbuk hospital pediatric ophthalmology clinic from 2010 to 2023. Ocular biometry was measured before and after instilling 1% cyclopentolate and 0.5% phenylephrine/0.5% tropicamide. Patients were categorized by strabismus diagnosis, age, refractive error and amblyopia status. Differences in AL, ACD, Km, WTW, and refractive error pre- and post-cycloplegia were analyzed using paired t tests. ACD (3.44 ± 0.33 vs 3.58 ± 0.29 mm, P < .05) and WTW (12.09 ± 0.42 vs 12.30 ± 0.60 mm, P < .05) increased significantly after cycloplegia in all groups except other strabismus subgroup (Cs) in both parameters and youngest subgroup (G1) in ACD. Refractive error demonstrated a hyperopic shift from −0.48 ± 3.00 D to −0.06 ± 3.32 D (P < .05) in overall and a myopic shift from −6.97 ± 4.27 to −8.10 ± 2.26 in high myopia (HM). Also, AL and Km did not change significantly. In conclusion, cycloplegia impacts ocular biometrics in children with strabismus and amblyopia, significantly increasing ACD and WTW. Refractive error shifts hyperopically in esotropia subgroup (ET) and myopically in high myopia subgroup (HM), eldest subgroup (G3) relating more to anterior segment changes than AL/Km. Understanding cycloplegic effects on biometry is important for optimizing refractive correction in these patients.

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The effect of cycloplegia on the ocular biometry and intraocular lens power based on age

Cited by 10 publications

References 32 publications

The Effect of Pupil Dilation on Biometry Measurements Obtained by AL-Scan in the Cataractous Eyes

The Effect of Pupil Dilation on Biometry Measurements Obtained by AL-Scan in the Cataractous Eyes

Changes in ocular biological parameters after cycloplegia based on dioptre, age and sex

Changes in ocular biometrics following cycloplegic refraction in strabismic and amblyopic children

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