2012
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Abstract: Peroxidase is the most important antioxidant enzyme in saliva. Through peroxidation of thiocyanate in the presence of H₂O₂, peroxidase catalyses the formation of bacteriocidic compounds such as hypothiocyanate.The purpose of this study was to evaluate the effect of chronic alcohol intoxication and smoking on the activity of oral peroxidase (OPO). A total of 37 volunteers participated in the study. This cohort consisted of 17 male alcohol-dependent smoking patients after chronic alcohol intoxication (AS group, … Show more

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“…It is also known that dental and oral hygiene is often neglected by persons addicted to alcohol and that cigarette smoking deteriorates oral hygiene and it is a strong modifiable risk factor for periodontal disease (Johnson and Guthmiller, 2007;Waszkiewicz et al, 2013b,c). In our present study, we confirmed our earlier reports (Waszkiewicz et al, 2012a(Waszkiewicz et al, ,c,d,e, 2013b that alcoholics have worse dental (reflected by higher DMFT) and periodontal state (reflected by higher GI and PBI) as well as lower SF, than the controls.…”
Section: Discussionsupporting
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“…It is also known that dental and oral hygiene is often neglected by persons addicted to alcohol and that cigarette smoking deteriorates oral hygiene and it is a strong modifiable risk factor for periodontal disease (Johnson and Guthmiller, 2007;Waszkiewicz et al, 2013b,c). In our present study, we confirmed our earlier reports (Waszkiewicz et al, 2012a(Waszkiewicz et al, ,c,d,e, 2013b that alcoholics have worse dental (reflected by higher DMFT) and periodontal state (reflected by higher GI and PBI) as well as lower SF, than the controls.…”
Section: Discussionsupporting
“…Some of exoglycosidases such as salivary, serum and urinary HEX, and serum MAN, as well as urinary product of FUC activity, α-fucose, were promoted as markers of chronic alcohol drinking (alcoholism) (Geokas and Rinderknecht, 1973;Wehr et al, 1991;Yamauchi et al, 1993;Stowel et al, 1997;Waszkiewicz et al, 2010bWaszkiewicz et al, , 2011aWaszkiewicz et al, , 2013bMaenhout et al, 2013). When serum and urinary exoglycosidases were proposed as markers of alcohol dependence, liver damage was described as a reason of their activity increase in the body fluids (Waszkiewicz et al, 2010b(Waszkiewicz et al, , 2012a.…”
Section: Discussionmentioning
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“…It has been shown that the health status of the oral cavity is influenced by the levels of ROS [24]. The oral cavity is often exposed to ROS due to intake of alcohol [25], cigarette smoke [25,26], medications, and diets rich in fat and protein [27,28]. Another important source of ROS in the oral cavity is the presence of inflammation for elimination of pathogens, e.g., bacteria and fungi.…”
Section: Introductionmentioning