The effect of Chlamydia trachomatis infection of the prostate gland on the concentration of citric acid

Zdrodowska-Stefanow, B; Ostaszewska-Puchalska, Iwona; Badyda, Jerzy; Galewska, Zofia

doi:10.1007/s00005-006-0009-z

Cited by 8 publications

(5 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Section: Discussionmentioning

confidence: 67%

“…The current study is a continuation of research whose results were published earlier [ 17 , 27 ]. In the study conducted in 2006 a relationship was found between C. trachomatis infection of the prostate gland and the level of citric acid in EPS [ 27 ]. Its continuation in 2007 demonstrated a correlation between the occurrence of anti- C. trachomatis antibodies in serum and prostatic secretions and the level of citric acid in the gland [ 17 ].…”

Section: Discussionmentioning

confidence: 67%

See 1 more Smart Citation

The evaluation of markers of prostatic inflammation and function of the prostate gland in patients with chronic prostatitis

Zdrodowska-Stefanow

Ostaszewska-Puchalska²,

Badyda³

et al. 2008

Arch. Immunol. Ther. Exp.

Self Cite

View full text Add to dashboard Cite

Introduction: The aim of the study was to determine the numbers of polymorphonuclear (PMN) leukocytes and PMN elastase and citric acid concentrations in chronic prostatitis patients regardless of etiology and in those with Chlamydia trachomatis infection of the prostate gland. Materials and Methods: The study involved 46 patients with chronic prostatitis. Expressed prostatitc secretions (EPS) were obtained to determine the leukocyte count, PMN elastase (ELISA) and citric acid concentrations (UV method), and the occurrence of C. trachomatis infection (ligase chain reaction). Results: Increased PMN cell counts (≥10 per high-power field) were found in 73.9% of patients and increased PMN elastase concentration (<250 ng/ml) in 78.3%. In 44.4% of the patients the elastase concentration indicated moderate (250-1000 ng/ml) and in 55.6% acute infection (≥1000 ng/ml). Decreased citric acid concentration (<18.12 mg/ml) in the EPS was found in 65.2% of the men. C. trachomatis prostate infection was detected in 17.4% of the patients and all of these men had higher inflammation parameters and lower citric acid concentrations. Conclusions: C. trachomatis prostate inflammation was accompanied by an increase in inflammation markers and a decrease in citric acid concentration.

show abstract

Section: Discussionmentioning

confidence: 67%

Section: Discussionmentioning

confidence: 67%

The evaluation of markers of prostatic inflammation and function of the prostate gland in patients with chronic prostatitis

Zdrodowska-Stefanow

Ostaszewska-Puchalska²,

Badyda³

et al. 2008

Arch. Immunol. Ther. Exp.

Self Cite

View full text Add to dashboard Cite

show abstract

“…A reduced concentration of citric acid in patients with detected infection of C. trachomatis suggests the existence of prostatitis induced by Chlamydia . In an earlier study we conducted research in the same group of patients evaluating the relationship between chlamydial prostatitis detected by means of direct tests (DIF, PCR) and citric acid concentration in the prostate gland [ 25 ]. We found that chlamydial infection of the prostate coexisted in all cases with a reduced concentration of citric acid, in most of the cases significantly.…”

Section: Discussionmentioning

confidence: 99%

Antichlamydial antibodies and citric acid in patients with chronic prostatitis

Ostaszewska-Puchalska¹,

Zdrodowska-Stefanow

Badyda³

et al. 2007

Arch. Immunol. Ther. Exp.

Self Cite

View full text Add to dashboard Cite

Abstract.IntroductionThe aim of the study was to evaluate the correlation between the presence of anti-C. trachomatis (C.t.) antibodies in serum and expressed prostatic secretions (EPS) and the concentration of citric acid in patients with chronic prostatitis.Materials and MethodsThe study involved 34 men with chronic prostatitis. The leukocyte count, presence of anti-C.t. antibodies (IgA, IgG), and citric acid concentration were determined in the EPS. The serum was examined for IgM, IgA, and IgG anti-C.t. antibodies. Specific antibodies were determined using the EIA method. The concentration of citric acid was measured using the ultraviolet method.ResultsInflammation of the prostate (≥10 PMN) was found in 61.8% of the patients. A reduction in citric acid concentration in the EPS was detected in 58.8% of the men. Specific serum antibodies were detected in 58.8% of the patients, including 23.5% with IgM, 32.4% with IgA, and 44.1% with IgG. In all patients, serum IgM and IgA antibody titers were low, while those of IgG antibodies were strongly positive in 46.7% of the patients. Anti-C.t. antibodies in the EPS were detected in 44.1% of the patients, including 32.4% with IgA and 35.3% with IgG. In contrast to serum, the titers of IgG antibodies in the EPS were low in all the patients, while those of IgA were strongly positive in 54.5% of cases. In patients with positive serological outcomes, 85% had reduced concentrations of citric acid.ConclusionsThe occurrence of anti-C.t. antibodies is usually accompanied by a decrease in the concentration of citric acid in the prostatic secretion.

show abstract

“…A reduction in the concentration of citric acid in EPS was observed in 56.7% of patients. In 88.2% of the patients, an elevated PMN count in the EPS accompanied reduced citric acid concentration [20].…”

Section: Chlamydiamentioning

confidence: 99%

Atypical infections of the prostate

Wise

Shteynshlyuger²

2008

Curr prostate rep

View full text Add to dashboard Cite

The effect of Chlamydia trachomatis infection of the prostate gland on the concentration of citric acid

Abstract: Determination of the concentration of citric acid in the prostatic fluid is a good indicator of prostatitis. C.t. infection of the prostate gland is accompanied by a decrease in the concentration of citric acid.

Cited by 8 publications

References 24 publications

The evaluation of markers of prostatic inflammation and function of the prostate gland in patients with chronic prostatitis

The evaluation of markers of prostatic inflammation and function of the prostate gland in patients with chronic prostatitis

Antichlamydial antibodies and citric acid in patients with chronic prostatitis

Atypical infections of the prostate

Contact Info

Product

Resources

About