Abstract:Intravenous administration of ovalbumin (1 mg kg−1) to guinea‐pigs that had previously been injected with 3.5 × 109 platelets from actively sensitized animals induced an approximately 40% decrease in the number of circulating leucocytes 30–60 min later, whereas the number of platelets was not affected.
In contrast, there was no change in the leucocyte number following antigen challenge of guinea‐pigs that had received platelets from non‐immunised animals.
This platelet‐dependent leucopenia was inhibited by pri… Show more
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