The Effect of a Corn Oil-Evaporated Milk Mixture on Serum Cholesterol Levels in Infancy

Pomeranze, Julius; Goalwin, Alta; Slobody, Lawrence B.

doi:10.1001/archpedi.1958.02060050626006

Cited by 11 publications

(2 citation statements)

References 6 publications

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“…As the infants of these two diet groups were given the same amount of calories and the same ingredients except for the fat, this difference cannot be ac¬ counted for by any other factor than the kind of fat supplied. Recently Pomeranze et al (1958) also observed a cholesterollowering effect of corn oil in normal in¬ fants, and a similar effect has earlier been demonstrated in normal adults (Ahrens; Malmros and Wigand, 1957) as well as in older children (Lindquist and Rafstedt, 1957). In the two last-mentioned age groups the effect, however, was not so readily noticeable in the values of the total lipids and the /?-lipoproteins as in the pres¬ ent series of newborns.…”

Section: Commentsupporting

confidence: 67%

Dietary Fat in Relation to Serum Lipids in the Normal Infant

Lindquist¹

1960

Arch Pediatr Adolesc Med

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Section: Commentsupporting

confidence: 67%

Dietary Fat in Relation to Serum Lipids in the Normal Infant

Lindquist¹

1960

Arch Pediatr Adolesc Med

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“…Pomeranze et al (19) showed that 50 g of corn oil added daily to an infant's evaporated milk formula significantly lowered serum cholesterol levels. Sweeney et al (24) found 30% lower values for plasma triglycerides, cholesterol and phospholipids and lower cholesterol/ phospholipid ratios in 6-week-old infants fed cow's milk formulas containing 10-15 calorie-% linoleic acid than in age-matched infants fed the same diet but with only 0.5 calorie% of linoleic acid.…”

Section: Concentration Of Main Lipid Classes In Plasmamentioning

confidence: 99%

Effects of Diet on Fatty Acid Composition of Plasma and Red Cell Phosphoglycerides in Three‐month‐old Infants

Olegård

Svennerholm

1971

Acta Paediatrica

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Summary Concentrations of the main lipid classes in plasma and the blood phosphoglyceride fatty acid patterns were measured in 3‐month‐old infants, fed breast‐milk or an industrial manufactured formula. The levels of cholesterol and phosphoglycerides were in the normal range for young adults, but the triglyceride concentration was twice as high as in adults. There were no significant differences in the levels of the plasma lipids between the two groups, but the mean of the triglycerides was 25 % higher in the formula‐fed group. The plasma and red cell phosphoglycerides had already assumed a fatty acid pattern of adult type. The concentration of the total polyenoic acids was significantly lower in the breast‐fed group, the difference being entirely confined to the fatty acids of the linoleic acid series. Linoleic acid was 27% and 40%, respectively, lower in plasma phosphoglycerides and red cell lecithin of breast‐fed than of formula‐fed infants, but arachidonic acid did not show any significant difference in the two groups. The concentration of the fatty acids of the linolenic acid series was higher in the breast‐fed infants. The blood lecithin ratio between the fatty acids of the linolenic acid series and the linoleic acid series was thus much lower in the formula‐fed than in the breast‐fed infants, the ratio being closely correlated with the dietary linolenate/linoleate ratio. Although the concentration of essential fatty acids was low in both plasma and red cell phosphoglycerides of breast‐fed infants, there was no increase of 20: 3 (n – 9).

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Concentrations of Cholesterol in Serum of Infants in Relation to Diet

Fomon¹

1960

Arch Pediatr Adolesc Med

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The demonstration of fatty streaking of the intima of arteries in the early months of life suggests the possibility that development of atherosclerosis may have its beginning at this age. Kube and Sslowjew1 rarely found fatty deposits in the aortas of stillborn infants or of those dying during the first month of life but were able to demonstrate such deposits in aortas of 66 of 80 infants (85.2%) dying between 1 and 6 months of age. Several authors have reported atherosclerotic changes in the coronary arteries in the early months of life,2-5 and Lober6 has demonstrated that the greatest annual change in infiltration of the intima occurs in the first year of life. The increased incidence of atherosclerosis in subjects with hypercholesterolemia has been amply documented, although it is not yet clear whether the association has etiologic significance.For the reasons mentioned, differences in concentrations of cholesterol in the blood of infants receiving various diets are of interest to pediatricians. The observations reported here concern the concentrations of cholesterol in the blood of infants receiving six different feedings.

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The Effect of a Corn Oil-Evaporated Milk Mixture on Serum Cholesterol Levels in Infancy

Cited by 11 publications

References 6 publications

Dietary Fat in Relation to Serum Lipids in the Normal Infant

Dietary Fat in Relation to Serum Lipids in the Normal Infant

Effects of Diet on Fatty Acid Composition of Plasma and Red Cell Phosphoglycerides in Three‐month‐old Infants

Concentrations of Cholesterol in Serum of Infants in Relation to Diet

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