The distribution of labdane diterpenes in the zingiberaceae of Malaysia

Terpenoids and a Diarylheptanoid from Zingiber ottensii

“…Similarly, the geminal protons of C-7 at δ 2.39 (ddd, J ) 13, 13, 4 Hz) and δ 2.66 (ddd, J ) 13, 6, 4 Hz) were correlated to the carbon at δ 213.0. These results suggested that compound 1 had a bicycle [7,4,0]tridecane skeleton.…”

“…The structures of the new compounds were determined to be 1,10,10-trimethylbicyclo [7,4,0]tridecane-3,6-dione (Rhizomes of many plants belonging to the genus Zingiber (Zingiberaceae) are used as spices or traditional folk medicines in many parts of the world. In the course of investigation of phytochemical constituents of the Zingiberaceae plants of Malaysia, 1a,b we focused on Zingiber ottensii Val.…”

“…Thus, the relative structure of compound 1 was defined as rel-1R,9S-1,10,10-trimethylbicyclo- [7,4,0]tridecane-3,6-dione. This is the first report of a compound having this skeleton as a natural product.…”

Advanced glycation end products inhibitors from Alpinia zerumbet rhizomes

“…The inhibitory effects of DK on human platelet aggregation, anti-inflammatory and cancer chemopreventive therapeutic properties are reported (Jantan et al, 2008). Labdadiene, isolated from the Zingiberaceae (Sirat, Masri, & Rahman, 1994), was traditionally used as a medicine against inflammatory diseases (Kunnumakkara et al, 2008). The cardiovascular effects induced by labdadiene were evaluated in male Wistar rats (Oliveira et al, 2006).…”

Supercritical Fluid Extraction (SFE) of Malaysian Wild Ginger Zingiber puberulum Inflorescence

“…Unfortunately, of the Zingiberaceae family, Z. puberulum is less known and studied compared to the common ginger, Z. officinale. Only work by Sirat and co-workers 19 found that the extract of Z. puberulum contained the labdane diterpenic constituents. Meanwhile, Theilade 20 documented the existence of Z. puberulum in Thailand ginger.…”