Supercritical Fluid Extraction (SFE) of Malaysian Wild Ginger Zingiber puberulum Inflorescence

Omar, Muhammad Nor; Razman, Summaiya; Nor-Nazuha, M. N.; Nazreen, M. N. M.; Zuberdi, Ahmad Muzammil

doi:10.13005/ojc/290114

Cited by 5 publications

(8 citation statements)

References 8 publications

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“…In the next step, by pressure reduction, the extract is separated from the solvent. This method has been used recently as an alternative to conventional techniques, such as steam distillation and extraction using organic solvents, because the resulting extract is richer in desirable compounds [ 51 , 61 ]. In practice carbon dioxide (CO 2 ) is used in most of analytical supercritical fluid extraction (SFE) processes due to several reasons.…”

Section: Different Extraction Methods Of Zermentioning

confidence: 99%

“…The main disadvantage of carbon dioxide concerns the extraction of polar analytes due to its lack of polarity. In the supercritical fluid extraction method, some solvents have been applied for a wide range of applications applications like extraction of metal cations and essential oils, and also the synthesis of polymers and particle nucleation [ 61 ].…”

Section: Different Extraction Methods Of Zermentioning

confidence: 99%

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A Review of the Biomedical Applications of Zerumbone and the Techniques for Its Extraction from Ginger Rhizomes

et al. 2017

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Zerumbone (ZER) is a phytochemical isolated from the subtropical Zingiberaceae family and as a natural compound it has different biomedical properties such as antioxidant, anti-inflammatory anti-proliferative activity. ZER also has effects on angiogenesis and acts as an antitumor drug in the treatment of cancer, showing selective toxicity toward various cancer cell lines. Several techniques also have been established for extraction of ZER from the rhizomes of ginger. This review paper is an overview of recent research about different extraction methods and their efficiencies, in vivo and vitro investigations of ZER and also its prominent chemopreventive properties and treatment mechanisms. Most of the studies mentioned in this review paper may be useful use as a knowledge summary to explain ZER extraction and anticancer activities, which will show a way for the development of strategies in the treatment of malignancies using ZER.

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Section: Different Extraction Methods Of Zermentioning

confidence: 99%

Section: Different Extraction Methods Of Zermentioning

confidence: 99%

A Review of the Biomedical Applications of Zerumbone and the Techniques for Its Extraction from Ginger Rhizomes

et al. 2017

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“…The powdered rhizomes of K. galanga were extracted using steam distillation and supercritical fluid extraction (SFE) according to previously reported methods 6,7,9 . For fractionation of ethyl p-methoxycinnamate (EPMC), the essential oil was stirred with boiling water and then recrystallized at cold temperature ( -4°C).…”

Section: E X T R a C T I O N A N D F R A C T I O N A T I O N O F E T mentioning

confidence: 99%

“…These include plant species from Alpinia 8 , Zingiber 9,10 , Galanga 10 and Kaempferia 6,7 . Cytotoxicity studies show that Kaempferia galanga extracts inhibited the proliferation of human cervical cancer C33A cell line 11 .…”

Section: Introductionmentioning

confidence: 99%

Cytotoxicity Activity of Biotransformed Ethyl p-methoxycinnamate by Aspergillus niger

Omar¹,

Hasali²,

Yarmo³

2016

Orient. J. Chem

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The extraction of Kaempferia galanga rhizome using steam distillation and supercritical fluid extraction (SFE) was carried out. After fractionation, the major compound of the K. galanga extract, ethyl p-methoxycinnamate (EPMC) was transformed using Aspergillus niger into ethyl p-hydroxycinnamate (EPHC). The biological anticancer activity of EPMC and its biotransformed product (EPHC) was established by cytotoxicity activity on the human breast cancer (MCF-7) cell line using MTT assay. Ethyl p-hydroxycinnamate (EPHC) was most cytotoxic against MCF-7 at 1000 µg/mL where percentage of cell viability was 9.87 %, while IC 50 was 340 µg/mL. EPHC showed slightly higher cytotoxicity activity compared to EPMC. The results of this study show that the biotransformation process was able to produce a metabolite (EPHC) with higher cytotoxicity activity compared to its parent compound (EPMC).

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“…The rhizomes were then extracted using steam distillation and supercritical fluid extraction (SFE) according to the previously reported method 23 . The essential oil was collected and stored at -4°C for future analyses.…”

Section: Extraction Of K Galanga Oil and Purification Of Ethyl P-metmentioning

confidence: 99%

Antimicrobial Activity and Microbial Transformation of Ethyl p-Methoxycinnamate Extracted from Kaempferia galanga

et al. 2014

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Supercritical Fluid Extraction (SFE) of Malaysian Wild Ginger Zingiber puberulum Inflorescence

Cited by 5 publications

References 8 publications

A Review of the Biomedical Applications of Zerumbone and the Techniques for Its Extraction from Ginger Rhizomes

A Review of the Biomedical Applications of Zerumbone and the Techniques for Its Extraction from Ginger Rhizomes

Cytotoxicity Activity of Biotransformed Ethyl p-methoxycinnamate by Aspergillus niger

Antimicrobial Activity and Microbial Transformation of Ethyl p-Methoxycinnamate Extracted from Kaempferia galanga

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