The Distribution of Endoscopic Gastritis in 25,536 Heath Check-up Subjects in Korea

Abstract

Background/Aims: Chronic gastritis is a common finding during endoscopy and it is very important to describe it correctly. This study was designed to evaluate the distribution of endoscopic gastritis and the differences according to age, sex or area. Materials and Methods: A clinical analysis was conducted on 25,536 subjects who had undergone an upper endoscopy for routine health check-up. Endoscopic gastritis was classified into four types, superficial gastritis, erosive gastritis, atrophic gastritis and intestinal metaplasia. The distribution of the four types of gastritis was evaluated according to sex, age and area. Results: 51.6% of the patients had experienced at least one of the symptoms (epigastric pain or discomfort, soarness, dyspepsia, abdominal pain) on at least a few occasions during the previous year. The incidence of normal gastric finding was 3,593 (14.1%). 21,943 (85.9%) subjects have at least more than one of endoscopic gastritis. The number of cases with superficial gastritis was 7,983 (31.3%), erosive gastritis 6,054 (23.7%), atrophic gastritis 6,918 (27.1%), and intestinal metaplasia 1,181 (7.1%). Erosive gastritis, atrophic gastritis and intestinal metaplasia were more frequent in men than women (P＜0.001) and in the older age group (≥60 years) than younger age group (P＜0.001). Conclusions: The prevalence of endoscopic gastritis was very common, 85.9%. In addition, erosive gastritis, atrophic gastritis and intestinal metaplasia were more frequent in men and in the older age group, which is similar to gastric cancer or peptic ulcer.

Review of Atrophic Gastritis and Intestinal Metaplasia as a Premalignant Lesion of Gastric Cancer

“… 42 A multicenter study of Republic of Korea in 2006, with 25,536 asymptomatic subjects assigned, evaluated that the prevalences of endoscopic AG and IM were 27.1% and 7.1%, which were lower than those estimated with histologic diagnoses. 43 The proportions of AG and IM in patients aged 40 years or less were 14.9% and 2.7%, and in those aged 60 years or more were 43.5% and 12.3%. This study showed that the prevalence of AG and IM increased significantly with age and male.…”

The prevalence of histologic atrophy and intestinal metaplasia in the corpus has decreased over 15 years in females in the Korean population

“… However, there was a sex difference in the pattern of gastritis in a multicenter study of 25 536 Koreans. For instance, the incidence of erosive gastritis, atrophy, and IM was higher in males than in females; thus, sex differences in addition to H pylori should be analyzed in terms of the prevalence or grade of atrophy/IM.…”

Atrophic Gastritis and Intestinal Metaplasia

“…The prevalence of AG and IM increased signifi cantly with age for both men and women [ 41 ]. When a multicenter study of South Korea in 2006, with 25,536 asymptomatic subjects, evaluated the prevalence of endoscopic AG and IM, they were 27.1 % and 7.1 %, respectively, which were lower than those estimated with histological diagnoses [ 42 ]. The proportions of endoscopic AG and IM in the patients aged 40 years or less were 14.9 % and 2.7 %, respectively, and in those aged 60 years or more were 43.5 % and 12.3 %, respectively [ 42 ].…”

“…The proportions of endoscopic AG and IM in the patients aged 40 years or less were 14.9 % and 2.7 %, respectively, and in those aged 60 years or more were 43.5 % and 12.3 %, respectively [ 42 ]. This study showed that the prevalence of AG and IM increased significantly with age and more frequent in male than in female [ 42 ]. Interestingly, the prevalence of endoscopic AG and IM were 40.7 % and 12.5 % in a multicenter study of 4,023 subjects in 2011, signifi cantly higher than those of a multicenter study in 2006 [ 43 ].…”

“…When a multicenter study of South Korea in 2006, with 25,536 asymptomatic subjects, evaluated the prevalence of endoscopic AG and IM, they were 27.1 % and 7.1 %, respectively, which were lower than those estimated with histological diagnoses [ 42 ]. The proportions of endoscopic AG and IM in the patients aged 40 years or less were 14.9 % and 2.7 %, respectively, and in those aged 60 years or more were 43.5 % and 12.3 %, respectively [ 42 ]. This study showed that the prevalence of AG and IM increased significantly with age and more frequent in male than in female [ 42 ].…”