The Development of Carbonate-containing Apatite/Collagen Composite for Osteoconductive Apical Barrier Material

New nanostructural biomaterials based on active silicate systems and hydroxyapatite: characterization and genotoxicity in human peripheral blood lymphocytes

“…, Takenaka et al . , Parirokh & Torabinejad ). The choice of such chemical composition and structural design was made with assumption that their chemical and mineralogical properties should enable biological responses similar to MTA and other biological cements, as well as adequate antimicrobial response in an aqueous environment due to their high pH (11 ‐ 13).…”

“…Despite its biocompatibility and satisfactory biological properties, difficult clinical manipulation due to its long setting time, as well as its high price, has prompted researchers to design alternative materials. New nanostructure materials based on calcium silicates and hydroxyapatite (HA) with advanced properties of setting time and decreased price have been developed recently (Asgary et al 2008, Takenaka et al 2008, Parirokh & Torabinejad 2010b. The choice of such chemical composition and structural design was made with assumption that their chemical and mineralogical properties should enable biological responses similar to MTA and other biological cements, as well as adequate antimicrobial response in an aqueous environment due to their high pH (11 -13).…”

Management of teeth with necrotic pulps and open apices

“…Takenaka et al. have described the properties of a new material formulated from carbonate‐containing apatite and collagen as an apical barrier with osteoconductivity.…”

“…The reinforcing effect and higher resistance to fracture was demonstrated by using a flowable, self‐cured intra‐canal composite , a resin glass ionomer , a special technique leaving a patent channel for Ca(OH) 2 replacement and subsequent obturation of the canal , and a technique described by Katebzadeh et al. , who compared an MTA plug backfilled with gutta‐percha and sealer.…”