The Dark Side of Beauty: Acne Fulminans Induced by Anabolic Steroids in a Male Bodybuilder

Kraus, Sigurd; Emmert, Steffen; Schön, Michael P.; Haenssle, Holger A.

doi:10.1001/archdermatol.2012.855

Cited by 37 publications

(13 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In addition to an acute exacerbation of acne vulgaris without apparent aetiology, acne fulminans has been described after testosterone treatment for excessive tall stature [7] , anabolic steroids for body building [8] , and androgen excess in the setting of lateonset congenital adrenal hyperplasia [9] .…”

Section: Discussionmentioning

confidence: 99%

Acne Fulminans: Treatment Experience from 26 Patients

et al. 2017

View full text Add to dashboard Cite

Background /Aim: Acne fulminans is a rare form of acne vulgaris with acute clinical deterioration including systemic signs. Etiopathogenesis and management remain largely unknown. Our aim is to assess the efficacy of a combined therapeutic regimen of systemic isotretinoin and prednisolone following the recent concepts of acne pathogenesis and drug kinetics. Methods: A prospective case series was recruited over 15 years. Isotretinoin 0.5 mg/kg bw/d (0.25-0-0.25) and prednisolone 30 mg/d (10-10-10) were administered concomitantly with prednisolone being tapered after that time. The overall efficacy was evaluated at month 1 and every month thereafter. Daily drug doses were split to reduce the risk for adverse effects. Results: 26 patients (20 male, 77%) at a mean age of 19 years and a history of acne vulgaris of 3.2 years presented acutely necrotic and ulcerating skin papules (100%), fever (45%), arthralgia (38.5%), leukocytosis (88.5%) and elevated erythrocyte sedimentation rate (100%). After one month of treatment resolution of systemic signs was achieved in all patients and a >50% skin lesion improvement in 17 patients (65%). Conclusion: The concomitant administration of isotretinoin (0.5 mg/kg bw/d, 0.25-0-0.25) and prednisolone 30 mg/d (10-10-10) is able to resolve systemic signs and markedly improve skin lesions in 65% of the patients at one month.

show abstract

Section: Discussionmentioning

confidence: 99%

Acne Fulminans: Treatment Experience from 26 Patients

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Moreover, AF has been described as a rare complication of high-dose testosterone therapy in adolescents with a hereditary tall stature 3 such as in bodybuilders following abuse of anabolic hormones. 4 …”

Section: Discussionmentioning

confidence: 99%

Acne fulminans associated with lymecycline intake: a case report

Gualtieri

Tonini

Panduri

et al. 2018

CCID

View full text Add to dashboard Cite

show abstract

“…[23] The attraction of anabolic agents apparently continues to be unconfined among cheating athletes and recreational sportsmen and women despite numerous comprehensive and new reports on health risks attributed to the abuse of AAS, [24,25] ranging from acne fulminans [26] over cardiovascular issues [27][28][29][30][31] to increased risk of breast and Leydig cell cancer [32,33] as well as psychic disorders and dependence. [23] The attraction of anabolic agents apparently continues to be unconfined among cheating athletes and recreational sportsmen and women despite numerous comprehensive and new reports on health risks attributed to the abuse of AAS, [24,25] ranging from acne fulminans [26] over cardiovascular issues [27][28][29][30][31] to increased risk of breast and Leydig cell cancer [32,33] as well as psychic disorders and dependence.…”

Section: Anabolic-androgenic Steroidsmentioning

confidence: 99%

Annual banned‐substance review: analytical approaches in human sports drug testing

Thevis

Kuuranne

Geyer

et al. 2013

Drug Testing and Analysis

View full text Add to dashboard Cite

Monitoring the misuse of drugs and the abuse of substances and methods potentially or evidently improving athletic performance by analytical chemistry strategies is one of the main pillars of modern anti-doping efforts. Owing to the continuously growing knowledge in medicine, pharmacology, and (bio)chemistry, new chemical entities are frequently established and developed, various of which present a temptation for sportsmen and women due to assumed/attributed beneficial effects of such substances and preparations on, for example, endurance, strength, and regeneration. By means of new technologies, expanded existing test protocols, new insights into metabolism, distribution, and elimination of compounds prohibited by the World Anti-Doping Agency (WADA), analytical assays have been further improved in agreement with the content of the 2013 Prohibited List. In this annual banned-substance review, literature concerning human sports drug testing that was published between October 2012 and September 2013 is summarized and reviewed with particular emphasis on analytical approaches and their contribution to enhanced doping controls.

show abstract

The Dark Side of Beauty: Acne Fulminans Induced by Anabolic Steroids in a Male Bodybuilder

Cited by 37 publications

References 5 publications

Acne Fulminans: Treatment Experience from 26 Patients

Acne Fulminans: Treatment Experience from 26 Patients

Acne fulminans associated with lymecycline intake: a case report

Annual banned‐substance review: analytical approaches in human sports drug testing

Contact Info

Product

Resources

About