The Cost-Effectiveness of Counseling Strategies to Improve Adherence to Highly Active Antiretroviral Therapy among Men Who Have Sex with Men

Zaric, Gregory S.; Bayoumi, Ahmed M.; Brandeau, Margaret L.; Owens, Douglas K

doi:10.1177/0272989x07312714

Cited by 30 publications

(57 citation statements)

References 135 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Counselling to improve adherence to HAART has been shown to increase length of life and modestly reduce HIV transmission (Zaric et al, 2008). The respondents in this study showed, with varied responses, that counselling does affect adherence to HAART:…”

Section: Counsellingmentioning

confidence: 87%

“…Counselling to improve adherence to HAART has been shown to increase length of life and modestly reduce HIV transmission (Zaric et al, 2008). The same study by Zaric and 48 colleagues (2008) also showed that counselling can provide significant benefit for individual patients, where there are limited resources, at an affordable cost.…”

Section: Social Supportmentioning

confidence: 96%

“…Counselling can therefore play a vital role in helping promote better adherence levels for those who are on HAART as it has been shown to increase length of life (Zaric et al, 2008).…”

Section: Counsellingmentioning

confidence: 99%

See 2 more Smart Citations

An investigation of the determinants of adherence to highly active anti-retroviral therapy in Aboriginal men in the Downtown Eastside of Vancouver.

Chongo¹

View full text Add to dashboard Cite

Section: Counsellingmentioning

confidence: 87%

Section: Social Supportmentioning

confidence: 96%

See 1 more Smart Citation

An investigation of the determinants of adherence to highly active anti-retroviral therapy in Aboriginal men in the Downtown Eastside of Vancouver.

Chongo¹

View full text Add to dashboard Cite

“…La bibliografía alrededor del modelado matemático de la transmisión del VIH y del SIDA es amplia, pero algunos modelos planteados en la literatura se han enfocado en el modelado de la infección y el tratamiento se citan algunos trabajos interesantes (4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15).…”

unclassified

Modelo de simulación para la infección por VIH y su interacción con la respuesta inmune citotóxica

Londoño-González¹,

Toro-Zapata²,

Trujillo-Salazar³

2014

Rev. salud pública

View full text Add to dashboard Cite

RESUMENCon base en ecuaciones diferenciales no lineales se formula un modelo matemático que describe la dinámica de interacción del VIH con células T CD4, que se considera que pueden ser activadas o no activadas en el reconocimiento de partículas virales; en cualquiera de los dos casos, son susceptibles a la infección con el virus. Se encuentran los puntos de equilibrio del sistema y en el caso particular del equilibrio trivial o de ausencia de infección, se determina su estabilidad local con base en el número básico de reproducción. Se efectúa además la simulación numérica del modelo para establecer el comportamiento que presentan las células infectadas y la carga viral, frente a variaciones de algunos de los parámetros. Finalmente, se reformula el modelo considerando respuesta inmune celular de tipo citotóxico y se realiza la simulación numérica.Palabras Clave: VIH, sistema inmunológico, dinámica de población, linfocitos t (fuente: DeCS, BIREME). ABSTRACTNonlinear differential equations were used for formulating a mathematical model describing the dynamics of HIV interaction with CD4 T-cells which are considered to be activated or not activated during recognition of viral particles; in either case they are susceptible to HIV infection. The system's equilibrium points were found and local stability was determined for trivial equilibrium or the absence of infection based on the basic reproduction number. The model was used for numerical simulation to show infected cell and viral load patterns regarding the variations of some parameters. The model was then reformulated, considering a cytotoxic cellular immune response and numerical simulation was run again.

show abstract

“…• availability of appropriate counselling (Knobel et al, 1999;Zaric, Bayoumi, Brandeau, & Owens, 2008);…”

Section: Adherence To Highly Active Antiretroviral Therapy: Barriers mentioning

confidence: 99%

'Experience talks, resilience shapes' revisiting historic trauma: impact on treatment in indigenous males living with HIV/AIDS in British Columbia

Chongo¹

View full text Add to dashboard Cite

There is an over-representation of HIV incidence, prevalence and mortality rates in the Indigenous population of Canada. Further, many do not adhere to HAART partly because of unresolved historic trauma (HT). Most research on HIV/AIDS therapy has focused on "maladaptive" characteristics of Aboriginal males and less on their adaptive, life-maintaining practices.This study explored the impact of HT on treatment among Indigenous males living with HIV/AIDS in BC, with a focus on adaptive/life maintaining practices, i.e., how the experience of HT positively affects male survivors' ability to adhere to treatment, and the HT impact on treatment outcomes across age groups and residential school survivor status.Using interpretive description incorporating a cultural safety lens as the methodological framework, data was collected through one-to-one interviews, a focus group, and a few Life Story Board sessions. Thirty-six HT survivors told their lived experience stories, discussed how HT affected their adherence to HAART, and explained how they build resilience.Three main themes resulted from data analysis: 1) facilitators of choice or actions leading to HAART adherence; 2) factors leading to HAART non-adherence; and 3) comparative survivor responses on health, services, stigma and the historic trauma effect.Adherence choices and actions are promoted by psychological support, cultural services, religion and spirituality, structural services, resilience, strictness and discipline metered on indirect survivors through their parents. Negative choice or actions resulted from; personal reasons, cultural restrictiveness, lack of structural support and services, spiritual and religionrelated factors, and intergenerational historic trauma effects. Finally, comparative responses of survivors' views noted included the view of health with respect to resilience, availability of and access to services on-and off-reserve, stigma and confidentiality, and the effect of historic iii trauma through generations and across survivor status. The findings demonstrate how complex the experience and expression of HT is and that most Indigenous men can be resilient to stay on HAART and have better health and wellbeing.Cultural-safety informed recommendations are offered to better address HT, improve treatment-adherent behaviour and resilience, foster healing and reduce deaths due to HIV/AIDS. This study suggests promising resilience factors that have implications for both research and practice.iv

show abstract

The Cost-Effectiveness of Counseling Strategies to Improve Adherence to Highly Active Antiretroviral Therapy among Men Who Have Sex with Men

Cited by 30 publications

References 135 publications

An investigation of the determinants of adherence to highly active anti-retroviral therapy in Aboriginal men in the Downtown Eastside of Vancouver.

An investigation of the determinants of adherence to highly active anti-retroviral therapy in Aboriginal men in the Downtown Eastside of Vancouver.

Modelo de simulación para la infección por VIH y su interacción con la respuesta inmune citotóxica

'Experience talks, resilience shapes' revisiting historic trauma: impact on treatment in indigenous males living with HIV/AIDS in British Columbia

Contact Info

Product

Resources

About