The correlation of serum nt-probnp levels of hemorragic and ischemic lesions detected with diffusion MRI in head traumas

Abstract

AIm:To evaluate the correlation between the dimensions of ischemic and hemorrhagic lesions detected by diffusion MRI and the changes in lesion dimensions with serum NT-proBNP levels in mild and moderate head trauma. mAterIAl and methOds: 30 patients were assessed in our study. A control group of 10 individuals with no trauma history was formed in order to establish normal serum NT-proBNP values. Patients underwent brain diffusion MRI 24 and 48 hours following admittance. Their plasma NT-proBNP levels were checked at the same stages. results:The correlation between the values of 24th and 48th hour Intra-axial hemorrhage (IAHEM) and Intra-axial ischemia (IAISC) and the values of 24th and 48th hour NT-proBNP was established as statistically significant. COnClusIOn:It was observed that the serum NT-proBNP values could be higher in patients with wide intra-axial lesion following head trauma than patients with smaller intra-axial lesions. In addition, the fact that it has been established that the serum NT-proBNP values of patients with increasing cerebral parenchymal lesion dimensions on the advancing hours after the trauma increase suggests that serum NTproBNP values may be significant in the follow-up of the dimensions of cerebral parenchymal damage. sOnuÇ: Serum NT-proBNP değerlerinin kafa travmaları sonrası intraaksiyal lezyonu geniş olan hastalarda daha küçük intraaksiyal lezyonlulardan yüksek olabileceği izlendi. Ayrıca travmanın ilerleyen saatlerinde serebral parankimal lezyon boyutları artan hastalarda serum NT-proBNP değerlerinin de artmasının belirlenmesi, serum NT-proBNP değerlerinin serebral parankimal hasarın boyutlarının takibinde önemli olabileceğini düşündürmektedir.