The comparative effects of 0.12% chlorhexidine and herbal oral rinse on dental plaque-induced gingivitis: A randomized clinical trial

Bhate, Devaki; Jain, Sanchit; Kale, Rahul; Muglikar, Sangeeta

doi:10.4103/0972-124x.153478

Cited by 12 publications

(15 citation statements)

References 8 publications

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“…When treated with chlorhexidine, herbal mouthwash, pomegranate peel extract 100%, and pomegranate peel extract 75%; the mean zone of inhibition against S. mutans is 15.92 mm, 30.15 mm, 17.47 mm, and 15.39 mm, respectively, as shown in Table 1 and Graph 1; and against lactobacillus, the mean zone of inhibition of these mouthwashes was 21.94 mm, 24.53 mm, 19.92 mm, and 17.31 mm, respectively, as shown in Table 2 and Graph 2. Herbal mouthwash had demonstrated a significant reduction in S. mutans and lactobacillus count.…”

Section: Resultsmentioning

confidence: 98%

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Comparative Evaluation of Antimicrobial Properties of Pomegranate Peel Extract Against Streptococcus Mutans And Lactobacillus - An In Vitro Study

Kunte¹,

Kadam²,

Patel³

et al. 2018

IDJAR

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Background: Dental caries is an infectious disease influenced by cariogenic microorganisms.Streptococcus mutans is associated with the initiation of caries, while lactobacilli with disease progression. Chlorhexidine is used as a gold standard mouthwash but with some side effects such as staining on long-term use. Nature itself is the best physician; it helps in treating oral health. Medicinal plants such as neem, tulsi, clove oil, triphala, and many more have been used in dentistry since ages to treat oral health problems such as bleeding gums, halitosis, and caries. One of them is pomegranate. It is the oldest edible fruit and considered as "a pharmacy unto itself. " Pomegranate has phenolic acids, flavonoids, and tannins in its different parts. Hydrolysable tannins called punicalagins which have free scavenging properties are the most abundant polyphenols found in pomegranate containing mouthwash. It has anticariogenic, anti-inflammatory, and antimicrobial properties. Aim: The aim of this study is to evaluate the antimicrobial efficacy of pomegranate peel extract, Hiora, and chlorhexidine. Materials and Methods: In this study, three different mouthwashes were used and divided into four groups as follows: Group A as chlorhexidine mouthwash (Hexidine), Group B as herbal mouthwash (Hiora), Group C as pomegranate peel extract 100% concentrated, and Group D as pomegranate peel extract 75% concentrated. Reference strains of S. mutans and Lactobacillus acidophilus were selected as it plays an important role in caries initiation and progression. S. mutans and Lactobacillus were grown in blood agar plates. For agar well diffusion method, wells of approximately 6-mm diameter and 4 mm in depth were made using a cork. In those wells, mouthwashes were added. Plates were incubated for 48 h at 37°C. The zone of inhibition was measured with the help of Vernier caliper. Results: The zone of inhibition of the solutions against S. Mutans and Lactobacillus shows a statistically significant P < 0.001** with f value of 1419.377 and 164.916, respectively. Conclusion: The pomegranate peel extract and Hiora show antimicrobial activities, and hence, they can be replaced for the long-term use to avoid the side effects of chlorhexidine mouthwash. Clinical significance: The pomegranate peel extract is a natural product with the antibacterial property; hence, it can be easily incorporated into oral hygiene measures such as mouthwashes or toothpastes.

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Section: Resultsmentioning

confidence: 98%

“…Kaim et al suggested that there are certain ingredients in herbal oral rinses that exhibit the evidence of antiinflammatory and antifungal therapeutic effects. [14] …”

Section: Discussionmentioning

confidence: 99%

Comparative Evaluation of Antimicrobial Properties of Pomegranate Peel Extract Against Streptococcus Mutans And Lactobacillus - An In Vitro Study

Kunte¹,

Kadam²,

Patel³

et al. 2018

IDJAR

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“…The findings of present study are in accordance with a study by Anup N et al, 12 who also demonstrated the efficacy of Hiora in reducing the plaque. Studies by Narayan A et al 13 & Bhate D et al 14 have also reported the efficacy of Hiora as a plaque reducing agent. In contrast to present study, Southern EN et al 15 have demonstrated Hiora to be ineffective compared to a placebo in relation to plaque reduction.…”

Section: Discussionmentioning

confidence: 97%

Comparative Evaluation of Efficacy of Hiora, Terminalia Chebula and Chlorhexidine as Mouth Wash on Dental Plaque

Gupta

Yadav

Khan

et al. 2017

JDHODT

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Introduction: Dental caries and periodontal diseases, the two arch criminals of oral cavity, are essentially caused by the microorganisms present in dental plaque. Aim and objectives: Evaluate the relative effectiveness of Chlorhexidine, Hiora, and T. chebula mouth rinses on plaque reduction. Materials and method: The present study was a randomized controlled crossover clinical trial. It was designed to evaluate and compare the efficacy of different mouth wash. Data obtained in relation to different assessing parameters at different phases of present study was subjected to statistical analysis using paired t-test. Results: Chlorhexidine was more effective in reducing dental plaque compare to other mouthwashes. Conclusion: Chlorhexidine shows better results compare to its herbal alternative but Hiora and Terminalia chebula mouthwash due to its natural ingredients has no reported side-effects and further studies with varied concentrations, different parameters and larger sample size are to be carried out to assess their efficacy of herbal mouthwash.

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“…4 Chlorhexidine has undesirable side effects, and one of the most common is staining of teeth. 5 Herbal mouthwashes are gaining popularity due to reduced side effects, 6 hence, there has been increased interest in plants with antibacterial and antiinflammatory activities. 7 One of the numerous herbal extracts, Green tea (Camellia sinensis) has numerous medicinal benefits, mainly due to its antibacterial and antioxidant properties.…”

Section: Introductionmentioning

confidence: 99%

Efficacy of green tea mouth wash as an adjunct to non-surgical periodontal treatment in patients with chronic periodontitis

Mustafa

Baban

2019

EDJ

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Background and objectives: Periodontal disease is the most common disease associated with microbial infection with the destruction of supporting structures. This study was carried out to evaluate the effectiveness of green tea as a mouthwash in the management of chronic periodontitis in comparison to chlorhexidine mouthwash. Patients and methods: A randomized controlled trial on 45 healthy humans with mild to moderate localized chronic periodontitis. They were randomly assigned into 3 equal groups (15 patients each), and they all received scaling and root surface debridement treatments. Group A used prepared green tea 5% as mouth wash for 2 weeks, group B used chlorhexidine mouthwash 0.12% for 2 weeks and group C did not use any mouth wash. Intra-oral clinical examination and blood samples collection were done for all patients for estimating the biochemical parameters C-reactive protein, alkaline phosphatase, Malondialdehyde at baseline and 30 days after periodontal therapy. For statistical analysis, SPSS program was used. Results: The study groups showed significant reduction in clinical periodontal parameters and inflammatory markers after 30 days of periodontal therapy (P<0.001). A significant difference was seen between group A and group B in relation to clinical periodontal parameters and inflammatory markers after periodontal therapy P<0.05, while the difference between group B and group C was non-significant in relation to gingival index, clinical attachment level, C-reactive protein, alkaline phosphatase, and Malondialdehyde. Conclusion: Green tea as a mouthwash could be an appropriate and effective choice as an adjunctive measure in the treatment of chronic periodontitis.

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The comparative effects of 0.12% chlorhexidine and herbal oral rinse on dental plaque-induced gingivitis: A randomized clinical trial

Cited by 12 publications

References 8 publications

Comparative Evaluation of Antimicrobial Properties of Pomegranate Peel Extract Against Streptococcus Mutans And Lactobacillus - An In Vitro Study

Comparative Evaluation of Antimicrobial Properties of Pomegranate Peel Extract Against Streptococcus Mutans And Lactobacillus - An In Vitro Study

Comparative Evaluation of Efficacy of Hiora, Terminalia Chebula and Chlorhexidine as Mouth Wash on Dental Plaque

Efficacy of green tea mouth wash as an adjunct to non-surgical periodontal treatment in patients with chronic periodontitis

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