Objective. Our aim was to explore the
relationship between vertigo symptoms and the prognosis of hearing
indicators in patients with sudden sensorineural hearing loss.
Data Source. Eligible studies were identified from the
“PubMed”, “EMBASE”, and “Web of Science” databases from January
2000 to September 2023. Study Selection. Studies were selected
from all original and retrospective or prospective studies that focused
on the relationship between vertigo and hearing prognosis in patients
with sudden sensorineural hearing loss. Data Extraction and
Synthesis. Observational metrics for data extraction included type of
study, number of subjects with or without vertigo, treatment regimen,
definition of pure tone hearing thresholds, criteria for hearing
improvement, treatment duration, follow-up time, and age distribution of
subjects. Meta-analysis was performed using Stata 15 software.
Main Outcome and Measure. Association of vertigo symptoms and the
prognosis of hearing indicators in patients with sudden sensorineural
hearing loss. Results.A total of 4290 patients with sudden
sensorineural hearing loss were identified in 23 studies. The hearing
recovery rate was 40.8% in the group with vertigo and 53.76% in the
group without vertigo. Vertigo was significantly associated with poorer
hearing recovery (OR = 2.13; 95% CI, 1.63-2.79; I =
68.3%). Subgroup analyses revealed similar results for medication
(OR=2.65; 95% CI, 1.84-3.83; I = 50.8%). However,
an attenuated association between vertigo and the prognosis of sudden
sensorineural hearing loss was observed in the subgroups treated with
drugs combined with hyperbaric chambers (OR= 1.76; 95% CI, 0.75-4.15; I
= 84.9%) and drugs combined with intratympanic
injections (OR= 1.62; 95% CI, 1.02-2.58; I =
65.6%). Conclusions and Relevance. Our study suggested that
vertigo may be a negative factor in sudden sensorineural hearing
loss.Based on the results of the subgroup analysis,the combined
treatment regimen has better efficacy in patients with sudden
sensorineural hearing loss with vertigo.