The Clinical Concept of Fibromyalgia as a Changing Paradigm in the Past 20 Years

Fitzcharles, Mary‐Ann; Yunus, Muhammad B.

doi:10.1155/2012/184835

Cited by 55 publications

(51 citation statements)

References 65 publications

(86 reference statements)

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“…In contrast, the EULAR assigned the highest level of recommendation to a set of pharmacological treatment. Predictors of outcome, favourable in over 50% of patients, are unknown, but those with better outcome do more physical activity and use fewer medication [30]. Interestingly, a meta-analysis shows that the magnitude of responders to placebo in drug trials of FMS is substantial.…”

Section: Fibromyalgia Syndromementioning

confidence: 99%

Is fibromyalgia part of the climacteric syndrome?

Blümel¹,

Palacios²,

Legorreta³

et al. 2012

Maturitas

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Section: Fibromyalgia Syndromementioning

confidence: 99%

Is fibromyalgia part of the climacteric syndrome?

Blümel¹,

Palacios²,

Legorreta³

et al. 2012

Maturitas

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“…48 Central sensitization, a concept developed by Muhammad Yunus, MD-while he was a professor of medicine at the University of Illinois College of Medicine and who is now a rheumatologist practicing in Peoria, Illinois-offers a unifying concept of chronic pain conditions being central sensitivity syndromes (CSS). 49 This concept is based on the biopsychosocial model of disease.…”

Section: Central Pain Sensitivitymentioning

confidence: 99%

Current Understanding of Fibromyalgia: Diagnosis, Treatment, and Theories About Causes

HorowitzSala¹

2015

Alternative and Complementary Therapies

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Fibromyalgia (FM) is a challenge to clinicians and patients because of its constellation of symptoms that are frequently shared with other chronic pain conditions, and the lack of a definitive diagnostic test or known cause. This article reviews the epidemiology, diagnostic issues and criteria, conventional and complementary and alternative medicine (CAM) therapies used to treat FM, the evidence base for CAM therapies, and theories of the causes of this complex disorder that affects the health-related quality of life (HRQoL) of millions of patients. Historical Background and EpidemiologyDerived from the Latin term for fibrous tissue (fibro) plus the Greek terms for muscle (myo) and pain (algia), FM is a disorder of unknown etiology characterized by chronic widespread pain and fatigue. 1 Symptoms may also include sleep disturbances, morning stiffness, cognitive problems, and depression. Although FM is often considered a rheumatic condition like arthritis, FM does not cause inflammation of-or damage to-the joints, muscles, or other tissues. The syndrome was called "fibrositis" prior to the mid-1970s. 2 The first controlled clinical study validating the symptoms of FM was published in 1981. The idea that FM was interconnected with similar conditions was also proposed in the 1980s. The American College of Rheumatology (ACR) published its first diagnostic criteria for FM in 1990, which were later revised.Recent estimates put the prevalence of FM in the United States as ranging from 2% to 8% of the population, second only to osteoarthritis (OA) as the most common "rheumatic" disorder. 3 The prevalence is similar in many other countries. The majority of patients affected are women, although FM can also affect men and children. Diagnostic Issues and CriteriaThere is currently no diagnostic test specifically for FM. In addition, many patients experience symptoms that also characterize other chronic pain disorders, including chronic fatigue syndrome, irritable bowel syndrome (IBS), temporomandibular disorders, and migraine. American College of Rheumatology CriteriaThe ACR developed criteria for classifying FM in 1990; this classification focused on tenderness upon pressure in at least 11 of 18 tender-point sites, in conjunction with widespread pain-defined as pain in 3 of the 4 quadrants of the body. No distinction was found between the diagnoses of primary and secondary FM, so the use of these terms was abandoned. 4 The ACR criteria accelerated research on FM, but were revised in 2010 in response to issues raised regarding the necessity of a tender-point-examination, lack of consideration of nonpain symptoms, and the observation that FM might represent the extreme end of a pain spectrum. 5 Daniel J. Clauw, MD-a professor of anesthesiology, medicine (rheumatology), and psychiatry at the University of Michigan in Ann Arbor, and director of the university's Chronic Pain and Fatigue Research Center-is among researchers who questioned the clinical utility of the ACR's emphasis on tender points in diagnosing FM. 6 Dr. Clauw com...

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“…Fibromyalgia syndrome (FMS) is a chronic health problem characterized by a wide range of physical and psychological symptoms such as chronic widespread pain, tender points, sleep disturbance, unrelenting fatigue, cognitive dysfunction, and substantial mood alterations that may lead to anxiety and depression (1,2).…”

Section: Introductionmentioning

confidence: 99%

The reliability and validity of the Turkish version of the Fibromyalgia Participation Questionnaire

et al. 2018

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Objective: The objective of this study was to test the reliability and validity of the Turkish version of the Fibromyalgia Participation Questionnaire (FPQ). Material and Methods: One hundred and eighty-four female patients with fibromyalgia syndrome were included in the study. All patients filled out the Turkish FPQ (FPQ-T) questionnaire, which was obtained by translation from German according to the guideline for the process of cross-cultural adaptation The patients filled out the revised Fibromyalgia Impact Questionnaire (FIQ) and reevaluated the FPQ-T two hours later. Internal consistency reliability of the FPQ-T was assessed by calculating the "if item deleted" using Cronbach's alpha and the "item-total correction" coefficient for each item of the questionnaire. The consistency of the subscales and the correlation of the test-retest values were assessed. The test-retest values were compared using the Wilcoxon test. Criterion validity was measured using FIQ scales by Spearman's rank correlation coefficient. Results: For internal reliability, Cronbach's alpha coefficient was calculated as 0.957 for nonworking patients and 0.958 for working patients. Cronbach's alpha values of 0.939, 0.871, and 0.914 were obtained for daily, social, and work life, respectively. Correlation coefficients were 0.888 for daily life, 0.859 for social life, and 0.901 overall in the nonworking group versus 0.896 the in working group. The comparison of scores obtained from test-retest measurements showed no significant difference except for Item 3. The correlation of the symptom severity score (SSS) and the FPQ-T was r=0.385 (p<0.001) and r=0.390 (p<0.001) for the nonworking and working subgroups, respectively. The evaluation of construct validity showed a significant correlation between the SSS and FPQ-T. Conclusion:The results of our study showed that the FPQ-T is reliable and valid for assessing participation and social functioning in fibromyalgia patients in Turkish society.

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The Clinical Concept of Fibromyalgia as a Changing Paradigm in the Past 20 Years

Cited by 55 publications

References 65 publications

Is fibromyalgia part of the climacteric syndrome?

Is fibromyalgia part of the climacteric syndrome?

Current Understanding of Fibromyalgia: Diagnosis, Treatment, and Theories About Causes

The reliability and validity of the Turkish version of the Fibromyalgia Participation Questionnaire

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