Is fibromyalgia part of the climacteric syndrome?

Blümel, Juan E.; Palacios, Santiago; Legorreta, Deborah; Vallejo, María S.; Sarrá, Salvador

doi:10.1016/j.maturitas.2012.06.001

Cited by 29 publications

(26 citation statements)

References 63 publications

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“…Sexual dysfunction can interfere in the quality of life and aggravate FM symptoms and depression, a frequent comorbidity of FM. The pathophysiological mechanisms seem to involve the peripheral and central nervous systems, hormones and/or immune-inflammatory mediators 4,8,9 , and hormonal variation associated with stress and the climacteric syndrome 16,17 . The search for clinical evidence is necessary to understand the role of comorbidities in FM and new possible approaches to assess these patients.…”

Section: Discussionmentioning

confidence: 99%

“…These are cytokine releasers that are found to be activated in FM 3,19,20,21,22,23 . The role of hormones in FM has been investigated, and the decline of sexual hormones in the climacteric syndrome could even be a potential etiology for FM 17 . Hormones are found to be altered in FM patients and they have direct influence in neurological and immunological functioning.…”

Section: Discussionmentioning

confidence: 99%

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Depression, sexuality and fibromyalgia syndrome: clinical findings and correlation to hematological parameters

Zakka

Teixeira

Kaziyama

et al. 2016

Arq. Neuro-Psiquiatr.

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Fibromyalgia (FM) is characterized by chronic pain and comorbidities. Objective To investigate sexuality and depression in women with FM compared with controls and to correlate the findings with hematological parameters. Methods 33 women with FM and 19 healthy women were included and evaluated with the following instruments: Female Sexual Function Index, Beck Inventory, Visual Analogue Scale, medical history and laboratory exams. Results The prevalence of sexual dysfunction (P = 0.007) and depression (P < 0.001) were higher in the study group than in the control group; they were positively correlated (P = 0.023). The study group showed lower serum concentrations of testosterone, free T4, antinuclear factor, and lower blood hemoglobin and hematocrit. Conclusions FM was associated with high scores of sexual dysfunction and depression, and there were correlations with hematological parameters. We suggest the involvement of immune-inflammatory mediators and FM, which need further investigation to understand their role in FM syndrome and its comorbidities.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Depression, sexuality and fibromyalgia syndrome: clinical findings and correlation to hematological parameters

Zakka

Teixeira

Kaziyama

et al. 2016

Arq. Neuro-Psiquiatr.

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“…Un estudio realizado en Finlandia determinó que los médicos generales piden exámenes de laboratorio a 12% de los pacientes con molestias musculoesqueléticas, imagenología a 24%, al 61% de los pacientes se le prescriben analgésicos, 16% van a kinesiólogo y 7% se deriva a especialista 10 . Muchas veces esta sintomatología osteomuscular es diagnosticada como fibromialgia, un cuadro con el cual la menopausia comparte similitudes no sólo sintomáticas, sino que también etiopatogénicas y terapéuticas, pudiendo, por lo tanto, la THM ser una alternativa terapéutica cuando otras terapias hayan fracasado 11 .…”

Section: Climaterio Y Calidad De Vidaunclassified

Los riesgos de no usar terapia hormonal de la menopausia: deterioro de la calidad de vida

Blümel

Arteaga

2017

Rev. méd. Chile

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“…Therefore, it is common that many patients initially seek medical care with generalist physicians and gynecologists, which reinforces the importance of investigating the association between menopause and fibromyalgia. 9,10 Studies examining this association have suggested that those hormonal disturbances of the menopause may be directly involved in the genesis of symptoms associated with fibromyalgia in middle-aged women. 10 However, considering that there are women with fibromyalgia outside the climacteric phase, it is clear that the hormonal deficit is not the only pathophysiological mechanism involved in the genesis of this disease.…”

Section: Introductionmentioning

confidence: 99%

“…9,10 Studies examining this association have suggested that those hormonal disturbances of the menopause may be directly involved in the genesis of symptoms associated with fibromyalgia in middle-aged women. 10 However, considering that there are women with fibromyalgia outside the climacteric phase, it is clear that the hormonal deficit is not the only pathophysiological mechanism involved in the genesis of this disease. 10,11 Despite the frequent association between climacteric syndrome and fibromyalgia, the literature is still scarce in terms of evidence from studies involved in the analysis and comparison of some related aspects, such as is the case of climacteric signs and symptoms, quality of life and sexual function.…”

Section: Introductionmentioning

confidence: 99%

Kinesiotherapy effect on quality of life, sexual function and climacteric symptoms in women with fibromyalgia

Lisboa

Sonehara

Oliveira

et al. 2015

Revista Brasileira de Reumatologia (English Edition)

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r e v b r a s r e u m a t o l . 2 0 1 5;5 5(3):209-215 w w w . r e u m a t o l o g i a . c o m . b r Quality of life Sexuality Sexual approach Climacteric a b s t r a c t Objective: To evaluate the effect of the kinesiotherapy in the quality of life, sexual function and menopause-related symptoms and compare in climacteric women with and without fibromyalgia (FM). Methodology: The group was composed of 90 climacteric women divided in 2 groups: FM (47) and control (43). The patients were analyzed on their quality of life (Utian Quality of Life [UQoL]), sexual function (Sexual Quotient-Female Version [SQ-F] questionnaire) and intensity of the climacteric symptoms (Blatt-Kupperman menopausal index [BKMI]). Both groups performed pelvic floor kinesiotherapy, composed of 20 sessions, twice a week. Statistical analysis was performed using Student's t-test, mixed-design analysis of variance (ANOVA) and Cohen's Kappa.Results: In the quality of life, an improvement was noticed in both groups for all domains analyzed. In the comparison between groups it was noticed a difference in the emotional (p = 0.01), health (p = 0.03) and sexual (p = 0.001) domains with considerable gains verified in the control group. Improvement was also noticed in the sexual function. In the analysis between groups, FM group showed a lower score compared to the control group (p < 0.001).With respect to the climacteric symptoms, there was no difference in the analysis between groups after the intervention (p < 0.001). Conclusions: The pelvic floor kinesiotherapy promotes a positive effect in the domains of quality of life, sexual function and climacteric symptoms in women with and without 210 r e v b r a s r e u m a t o l . 2 0 1 5;5 5(3):209-215fibromyalgia in the climacteric period; however, fibromyalgia seems to be a limiting factor to achieve better results in some of the aspects evaluated. Efeito da cinesioterapia na qualidade de vida, função sexual e sintomas climatéricos em mulheres com fibromialgiaPalavras-chave: Fibromialgia Qualidade de vida Sexualidade Abordagem sexual Climatério r e s u m o Objetivo: Avaliar e comparar o efeito da cinesioterapia na qualidade de vida, função sexual e sintomas climatéricos em mulheres climatéricas com e sem fibromialgia. Métodos: Participaram 90 mulheres climatéricas, divididas em dois grupos: fibromialgia (47) e controle (43). As pacientes foram avaliadas nas variáveis: qualidade de vida (Utian Quality of Life [UQOL]), função sexual (questionário do quociente sexual/versão feminina [QS-F]) e intensidade dos sintomas climatérios (Índice Menopausal de Blatt-Kupperman [IMBK]). Os grupos fizeram cinesioterapia para o assoalho pélvico, composto de 20 sessões, duas vezes por semana. Análise estatística foi feita por meio dos testes t de Student pareado, análise de variância de delineamento misto e Kappa de Cohen.Resultados: Na qualidade de vida, foi observada melhoria em ambos os grupos para todos os domínios avaliados. Na análise intergrupo foi evidenciada diferença nos domínios emocional (p = 0,01), saúde (0,...

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Is fibromyalgia part of the climacteric syndrome?

Cited by 29 publications

References 63 publications

Depression, sexuality and fibromyalgia syndrome: clinical findings and correlation to hematological parameters

Depression, sexuality and fibromyalgia syndrome: clinical findings and correlation to hematological parameters

Los riesgos de no usar terapia hormonal de la menopausia: deterioro de la calidad de vida

Kinesiotherapy effect on quality of life, sexual function and climacteric symptoms in women with fibromyalgia

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